1. [Neuromyelitis optica is a frequently seen inflammatory demyelinating disease].
- Author
-
Asgari N, Skejø HP, Lillevang ST, and Stenager E
- Subjects
- Aquaporin 4 cerebrospinal fluid, Aquaporin 4 immunology, Autoantibodies cerebrospinal fluid, Autoantibodies immunology, Humans, Immunoglobulin G cerebrospinal fluid, Magnetic Resonance Imaging, Myelitis, Transverse etiology, Neuromyelitis Optica classification, Neuromyelitis Optica epidemiology, Neuromyelitis Optica immunology, Optic Neuritis etiology, Neuromyelitis Optica diagnosis
- Abstract
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system with autoimmune characteristics. Serum immunoglobulin G autoantibodies have been identified in the majority of NMO patients with the water channel aquaporin-4 (AQP4) as their main target autoantigen. Clinical criteria have defined NMO and NMO-spectrum disease. The clinical features include inflammation of the optic nerve.
- Published
- 2013