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På linje med de øvrige lande i EU har Danmark valgt at bruge FAIR (Findable,Accessible,Interoperable,Reusable) som model for data management af offentligt finansierede forskningsdata. Derfor har Uddannelses- og Forskningsministeriet gennem DeiC fået udarbejdet en national strategi for data management baseret på FAIR principper, som blev offentliggjort i 2021. Strategien gælder for offentligt finansierede forskningsdata, forstået som resultatet af forskning finansieret af offentlige midler eller forskning udført af offentlige institutioner, hvor der er inkluderet privat finansiering. Strategien er udformet i overensstemmelse med Direktivet om Åbne Data - artikel 10 og med forslaget til den danske PSI-lov. Som en del af strategien nedsatte Uddannelses- og Forskningsministeriet en følgegruppe med den opgave at følge og koordinere implementeringen af strategien. Strategien indeholder en række principper og forslag til indsatser, der skal understøtte strategiens realisering. Følgegruppen skal særligt fokusere på den del af implementeringen, som kræver en national koordinering på tværs af interessenter (eksempelvis forskningsinstitutioner og DeiC). Følgegruppen har, som en del af sin opgaveportefølje, udarbejdet en handlingsplan for koordinering, opfølgning og prioritering af de indsatser, som kræver en særlig national tilgang. Nærværende rapport er en statusrapportering for handlingsplanen. Forslaget til handlingsplanen lægger desuden op til overvejelser mht. fordele og ulemper ved, at de forskningsfinansierende fonde stiller krav til bevillingsmodtagere om udarbejdelse af FAIR-baserede data management planer. Følgegruppen har nedsat 5 tværinstitutionelle arbejdsgrupper med det opdrag at følge hver deres indsatsområde. Følgegruppen har derudover valgt at fokusere på effektiv kommunikation, dels som redskab mellem arbejdsgruppernes medlemmer, dels i forhold til at skabe en national ramme for let tilgængelig og let forståelig information om data management baseret på FAIR Principperne for universiteterne. Det anses som en absolut nødvendighed, da implementeringen af FAIR må anses for en af de største samlede kultur- og praksisændringer forskningsverdenen har oplevet i nyere tid.

invited speak in the occasion of 40 years of Greenland TV (KNR): - Ataqatigiinneq, assigiinngissuseq aammalu assigiinngiiaarneq Siunissami tamanut kiffartortussaatitaanermi eqqarsaatit, algoritmi aammalu inuttut pissusilersuineq aallaavigalugit

Endometriosis affects an estimated 200 million people worldwide. Despite its prevalence, those living with the disease often wait an average of 7.5 years between start of symptoms and diagnosis. This delay is due to a variety of reasons, including medical dismissal, a low prioritization of the condition and its overall misrepresentation in research funding, policy and media.Although often represented as a women’s reproductive disease, endometriosis also appears in people who have had hysterectomies, transgender men, genderfluid and non-binary people, pre-menstrual and post-menopausal people, and in rare cases, cisgender men.Its symptoms commonly include pain with menstruation, as well as chronic pain, infertility, pain with sexual intercourse, fatigue and more. Despite this full-body impact on one’s quality of life, endometriosis is commonly associated with just having “bad periods.”We are four authors from three countries looking at different aspects of endometriosis diagnosis, awareness and patient advocacy. This article emerges from a joint online presentation of our research looking at potential ways to improve awareness and patient care, and promote faster diagnosis.Our methods include social scientific and qualitative research including interviews, surveys, focus groups, participant observations and collaborations with people living with endometriosis. We identified some clear changes that are needed to promote awareness of the disease, and subsequently reduce diagnostic timelines.

COVID-19 is the infectious disease caused by coronavirus SARS-CoV-2. The most common symptoms of COVID-19 are dry cough, tiredness and fever. Most patients recover from COVID-19 within a few weeks, but some patients have symptoms lasting for weeks or even months after recovery from acute illness, such as fatigue, shortness of breath and cough. This is a review of what we currently know about the clinical disease and its severity as well as which diagnostic strategies are recommended during and after hospital admission. COVID-19 is the infectious disease caused by coronavirus SARS-CoV-2. The most common symptoms of COVID-19 are dry cough, tiredness and fever. Most patients recover from COVID-19 within a few weeks, but some patients have symptoms lasting for weeks or even months after recovery from acute illness, such as fatigue, shortness of breath and cough. This is a review of what we currently know about the clinical disease and its severity as well as which diagnostic strategies are recommended during and after hospital admission.

This thesis explores the challenges which unemployed academic graduates experience in the Danish employment system and how this area can be improved from their point of view.Based in action research and critical theory, the research aims to contribute to an improved and integrated process for unemployed graduates.The methodology utilises qualitative methods grounded in action research, specifically in terms of a future workshop and eight interviews. Perspectives from all empirical partners are integrated into the analysis of the ideal employment area. The theoretical position used in the analysis is based on Andersen and Bilfeldts theory of Critical Transformational Empowerment; Honneth’s Three Spheres of Recognition; Rosa’s understanding of Acceleration and Alienation; and Trust - and Systems Theory by Luhmann.The conclusions show that the meeting between the unemployed and the job consultants could benefit from more continuity, a holistic approach and trust. Furthermore, it is essential that university lecturers become more aware of job opportunities outside traditional research environments. This will secure an integrated transition between university and employment. Finally, it is imperative to improve the cooperation between all participants in the field, and reconsider possible barriers to the transition from studies to relevant employment. The research shows it is essential to create a more inclusive and healthy promotional employment arena.

Background Genetic risk scores (GRSs), based on variants identified in genome-wide association studies (GWAS), have been shown to predict risk of coronary artery disease (CAD). However, the clinical potential remains unknown. Purpose To investigate whether a GRS improves discrimination of hemodynamically obstructive CAD beyond the CAD Consortium scores and coronary artery calcium score (CACS) in patients referred for coronary computed tomography angiography (CTA). Methods We consecutively included and genotyped 1645 patients undergoing CACS scoring and coronary CTA on a suspicion of CAD. Using LDPred, a recently validated GRS was calculated as the weighted sum of the number of CAD risk variants identified from the CARDIoGRAMplusC4D GWAS meta-analysis. Patients with a ≥50% stenosis on CTA further underwent invasive coronary angiography (ICA) with fractional flow reserve (FFR). Hemodynamically obstructive CAD was defined as a visual ICA stenosis >90%, FFR 50% if FFR was not feasible. Discrimination was evaluated by receiver-operating characteristics. Results Median age was 57 (interquartile range 50-64) years and 799 (49%) were males. Hemodynamically obstructive CAD was present in 14 (4%) with a low GRS (80th percentile) (p0.05). Conclusion A GRS improves discrimination of hemodynamically obstructive CAD beyond CAD consortium scores, particularly in young women. However, the additive discriminative value is attenuated in models including CACS.

Skift af efteruddannelsesfokus fra fælles kurser med undervisning centralt opbrydes, og undervisning i decentrale grupper vinder terræn. Men hvor kom ideen fra, og hvor langt er vi i Danmark?

Praktiserende læger er via nuværende overenskomst enten forpligtet til deltagelse i klyngearbejde eller en ny akkreditering. Ud fra et internationalt perspektiv gennemgås fordele og faldgruber.

WONCA Europes netværk for kvalitetsudvikling og patientsikkerhed (EQuiP) har meldt markant ud vedrørende brugen af kvalitetsindikatorer. Privatlivet skal respekteres, og kvalitetsindikatorer kan kun bruges i begrænset omfang i internt kvalitetsudviklingsarbejde og da ikke som et direkte mål for kvalitet. Væsentligt er det, at der ikke kan påvises nogen nytte af at bruge kvalitetsindikatorer til at honorere ydelser efter.

INDHOLDSFORTEGNELSE Introduktion Definition og begrebsafklaringSammendrag af 2012 rapporten ”Maximal medicinsk uræmibehandling (MMU) og palliativ indsats i nefrologi” Landsdækkende tværfagligt palliations udvalg Identifikation af MMU patienter (screening) Information til ambulante patienter Fokus ved MMU MMU i relation til palliation Forslag til opbygning af ambulante MMU forløb Tværprofessionelt samarbejde MMU og palliation i sengeafdeling Palliative tilbud til dialysepatienter og afslutning af dialyse behandling Eksempler på uddannelsestilbud Forskning Visioner 2020 Relevante linksReferencerBilag

I artiklen bliver det fremlagt, hvordan skrofulose blev forstået og klassificeret som selvstændig sygdom i en dansk medicinhistorisk kontekst omkring overgangen til det 20. århundrede. Niemeyer, der var eksponent for naturlægemetoden, troede fuldt og fast på, at en usund næringsvæskesammensætning var hovedårsagen til skrofulose. Geill, der forstod kirtelsyge som en tuberkuløs sygdomstilstand, mente omvendt, at skrofulose reelt skulle opfattes som forstadium til lungetuberkulose.Hvor Niemeyer og Geill altså var dybt uenige om årsagerne til skrofulose – ikke mindst eksemplificeret ved deres vidt forskellige syn på arvelighedsforhold – var de rørende enige om, at frisk luft, hudpleje, ernæring og legemsbevægelse var de mest effektive midler til at forebygge sygdommen og reducere smittefare samt minimere risikoen for, at et svageligt barn blev eksponeret for slette livsforhold, der kunne føre til skrofulose.

Taking its point of departure in recent considerations of the notion of post-pastoral literature as capable of inducing awe in readers, this article discusses the work of words and books analysed and performed by Robert Macfarlane’s Landmarks (2015) in terms of vastness and accommodation., Akademisk kvarter | Academic Quarter, Art's Agency

Despite an increase in the total number of tuberculosis (TB)patients globally, positive trends in reduction of prevalenceand mortality are observed. However, high numbers of drugresistantcases are threatening this trend. Multidrugresistantand extensively resistant cases constitute anincreasing challenge in many parts of the world also withinthe European region – especially in former Sovjet Republicnations. Point-of-care test systems potentially replacingmicroscopy and urine antigen detection systems arecurrently launched in many TB-high endemic countries andimproving TB detection rates. However, the effect on keyindicators like mortality is still waiting to break through. Despite an increase in the total number of tuberculosis (TB) patients globally, positive trends in reduction of prevalence and mortality are observed. However, high numbers of drug-resistant cases are threatening this trend. Multidrug-resistant and extensively resistant cases constitute an increasing challenge in many parts of the world also within the European region - especially in former Sovjet Republic nations. Point-of-care test systems potentially replacing microscopy and urine antigen detection systems are currently launched in many TB-high endemic countries improving TB detection rates. However, the effect on key indicators like mortality is still waiting to break through.

Konceptet Praksis Plus er en hjælp og støtte til nynedsatte alment praktiserende læger i de indledende, skrøbelige karriereår. I denne artikel beskrives den gensidige inspiration fra udlandet.

This paper investigates women in IRIB commercials and compares their depiction on television to their status in Iranian society. The research consisted of systematically collecting commercials from IRIB television broadcast and then analyzing them quantitatively and qualitatively. The results were compared against demographic statistics to see how and to what degree television portrayals of women differ from women in real life. This research finds that women are significantly absent from IRIB television commercials, and when they do appear, they are portrayed in traditional and stereotypical roles such as wife and mother. The commercials overwhelmingly feature men, and men are portrayed in positions of power. Some suggestions explaining the dissonance between the television commercials and everyday life are offered.

Chronic alcohol abuse can cause both acute and chronic health problems. Unfortunately, sudden cessation is problematic, with risk of complications ranging from mild to lethal. We report a case of a 60-year-old man with substantial alcohol abuse, who suffered cardiac arrest after sudden withdrawal of alcohol. No other cause of death was found despite thorough examination. Alcohol withdrawal syndrome is a potentially fatal condition and the risks of sudden withdrawal should be recognized and treated.

Arbejdet med at lette overgangen fra uddannelseslæge til praktiserende læge via en elektronisk håndbog er gået ind i sin afsluttende fase. Der er nu fokus på at producere, redigere og på at reflektere over processen. At se både bagud, ligeud og fremad.

Publikationen er skabt af partnere i konsortiet UNIK, hvis formål er atudvikle ny og innovativ teknologi til kroniske patienter.

Dette kapitel undersøger den tidsmæssige effekt af et præhospitalt beredskab, hvori der indgår en akutlægehelikopter versus et beredskab, hvor udelukkende ambulancer benyttes til transport af patienter.Fokus er rettet mod specifikke patientgrupper, der er i tidskritiske tilstande, hvor det er vigtigt at de tidligt tilses og behandles af speciallæge, og hvor højt specialiseret behandling skal iværksættes hurtigt for at opnå højere overlevelse og bedre outcome.

Resuscitation after cardiac arrest is unlikely if a reversible cause is not identified and treated. The potentially reversible causes can be described as hypoxia, hypovolaemia, hypo-/hyper-kalaemia/other metabolic disorders, hypothermia and tension pneumothorax, tamponade (cardiac), toxins and thrombus. We report a case in which thrombolysis was used successfully during prolonged resuscitation. The patient was later confirmed to have had a massive pulmonary embolus. He was discharged to his home 13 days after cardiac arrest without any sign of neurological deficit.

Når man arbejder med innovation i praksis og herunder skabelsen af nye ideer via input fra forskellige brugere, er forfatternes erfaring den, at såvel ledelsesmetode som den operationelle proces oftest tages for givet af de ansvarlige. Dette har skabt en undren, som vi ønsker at belyse via denne artikel. Vi præsenterer og sammenligner resultaterne fra fire forskellige casestudier med forskellige set-up, som alle blev gennemført i samarbejde med fi re forskellige virksomheder i forbindelse med BDI-projektet ’Handyvision’. Casestudierne opdeles således: Case a) workshoplederen faciliterer og deltagerne er fysisk tilstede Case b) workshoplederen konsulterer og deltagerne er fysisk tilstede Case c) workshoplederen faciliterer online kommunikationsplatform Case d) workshoplederen konsulterer online kommunikationsplatform Vores analyse indikerer, at facilitering hovedsageligt skaber ideer til inkrementel innovation og konsultering giver større potentiale for radikal innovation. Samtidigt opstiller vi på baggrund af analysens resultater 6 suppositioner, som bør undersøges nærmere. I artiklen introducerer vi desuden begrebet Near Lead Users.