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The aim of the bachelor thesis is to identify the main representatives of a wide group of Pharmaceuticals and personal care products (PPCP for short) and to explain the reasons why they pose an increasing risk to aquatic ecosystems. In the theoretical part, the work is devoted to defining the concept of PPCP and explaining the main reasons why their concentration in the aquatic environment has been growing steadily in recent decades. It also deals with the division into the main groups of preparations found in the aquatic environment, their characteristics, documented impacts on aquatic organisms and currently detected concentrations in the world's rivers. In the following chapters, the thesis addresses the issue of the effectiveness of the removal of these substances and the mechanisms by which they can be improved. The work briefly summarizes the effects on the organisms caused by both bioaccumulation and endocrine disruption and at the end of the theoretical part deals with the properties of ten selected drugs, which are regularly detected in Czech rivers. The practical part evaluates the volume of sales of ten drugs in the Czech Republic during 2019, their detected concentrations in the rivers Vltava, Elbe, Morava and Dyje and processing these data to assess the risk of concentrations found for...

The "Zákolanský potok" takes part in European nature program Special Area of Conservation because of the presence of stone crayfish (Austropotamobius torentium), which is listed as threatened species. The area around brook is intensively agriculturally cultivated. Water from wastewater treatments plants is drained to the local brooks. The aim of the work was to describe diversity of macrozoobenthos on the brook called "Zákolanský potok". Further aim was to evaluate the ecological condition of the watercourse using biotic indexes. The samples of macrobenthos were taken from three profiles in five sampling periods. Profile 1 was control, profile 2 was under the wastewater treatments plants and the third profile was placed down the stream. Diversity, biomass, saprobic index, BMWP, and ASTP scores were evaluated for the community of macrozoobenthos. The saprobic index was evaluated to the beta-mezosaprobity value (2.0-2.4) in the first profile, the saprobic index on the second profile showed a relatively wide range from worse oligosaprobity to worse beta-mesosaprobity (1.2-2.4). On the third profile, the saprobic index ranged from better beta-mesosaprobity to better alpha-mesosaprobity (1.6-2.6). The BMWP and ASPT scores in all profiles refer to medium to low quality aquatic environments. The diversity of the community gained the best values on the 3rd profile, here was found with one more taxon than on the 1st profile. With increasing organic load, diversity decreased on the 2nd profile, although a more sensitive species was found here.

In August 2014 a total die-off of fish stock occurred in Záhumenní velký, a pond with a surface area of 5.85 ha. The investigation of the fish kill revealed that the Jabkenice WWTP located above the pond area had discharged water of inappropriate quality (N-NH4+ -99.3 mg/l-1) into the pond. This event resulted in the monitoring of physical and chemical parameters of water quality, zooplankton sampling and measuring of growth dynamics of fish stock by using control reduction fishing. The survey conducted in 2015 studied three different ponds (Ohrada 0.85 ha, Záhumenní velký 5.85 ha and Vlkava 22.1 ha), located in the fertile lowland areas around Mladá Boleslav where pre-cleaned sewage water from the sewage treatment plants flows. The water samples taken both at the outflow of the waste water treatment plant and in the pond were analysed in an accredited laboratory. The following parameters were examined: BOD5, TN, CODCr, ammoniacal nitrogen, TP, nitrites, nitrates and others.

The aim of this bachelor thesis was to make an overview of distribution of beta-blockers and calcium channel blockers, their occurrence in aquatic environment and their impact on fish. Analysis of data obtained from the website of the State Instiute for Drug Control, which was carried out in Excel revealed, that 53 643 kilograms of beta-blockers and 24 472 kilograms of calcium channel blockers was distributed in the Czech Republic in 2011. Metoprolol, acebutlol and atenolol reached the largem volume of distribution among aktive ingredients in the group of beta-blockers. Verapamil, amlodipin and diltiazem were TOP 3 calcium channel blockers. These drugs are generally the most sold in the world and they can be found in surface waters in the Czech Republic and worldwide at concentrations rating from tens to hundreds ng.l-1 . The reason for this is the low removal rate of beta-blockers and calcium channel blockers in wastewater treatment plants, which ranges from 11 to 76%. Toxicity tests on fish with metoprolol, propranolol, atenolol, verapamil and diltiazem have shown the effect of this pharmaceuticals on e.g., reduction of fecundity, hatchability or heart rate. Various histopatological changes on the liver and heart or malformations of early developmental stages of fis have been also reported. The lowest concentrations of the tested substances at which these effects were observed, ranged mostly from values g.l-1 to mg.l-1, i.e. these concentrations were higher than those commonly found in surface waters. However, some effects were observed also at environmentally relevant concentrations. Due to prolong-term exposure on the organisms beta-blockers and calcium channel blockers may represent a threat to aquatic ecosystems. A solution could be to improve the mechanism for removal of pharmaceuticals in the sewage treatment plants.

The main goal of bachelor piece was to describe actual marketing mix in the chosen company and after then propose suitable innovation of marketing mix.

Some 30 - 50 % of municipal solid waste (MSW) is biodegradable waste. Most of this waste is sent to landfills or incinerated and is not recovered. According to Waste Management Plan of Czech Republic based on the Landfill Directive of EU, Czech Republic should to reduce weight of biodegradable waste sent to lanndfills to 75 % in 2010 and 35 % in 2020 compared with the amount that had been landfilled in 1995. In rural areas biodegradable waste is fed to animals or treated by home composting. However in urban areas the collection of separated biowaste is problem for a long time. Food waste disposers (FWDs) presents interesting alternative for the biowaste disposal. They enable the separation of food waste at source by shreding it in a kitchen sink. FWDs utilize existing infrastructure of sewer system to transport shreded wastes to wastewater treatment plants (WWTP). Wastes can be disposed in WWTPs by anaerobic digestion - the best method for disposal of food waste of animal origin. This work concentrates on literature research of studies about feasibility of FWD as a instrument for biodegradable waste removal and compares arguments for and against using of FWDs in households. Majority of studies shows no complications in sewer system and on WWTP after instalation of FWDs. Energetic and hydraulic consumption...