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Ultrasound method belongs to the most extended and easily available modern investigative diagnostic techniques. It is the step number one in the investigative diagnostic algorithm. The beginning of this method dates back to the early fifties of the twentieth century. With respect to the fact that the usage of ultrasound contrast agents and the development of an {\clqq}optimal`` contrast agent has not finished, I refer to some limitations and obstacles. Although this process is similar for all contrast agents in all fields of modern imaging methods. Implementing new findings and observations into a clinical practice is connected with lots of difficulties and obstacles that restrain their success. In the same way as the contrast agents found their application in various modern imaging techniques, the ultrasound contrast agents are also expected to find their place in the ultrasonography. This fact acknowledges my hypothesis and points at application of ultrasound method as the first choice.