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Učestalost migrene sve više raste, ali uzroci i mehanizmi ove bolesti i dalje ostaju nerazjašnjeni. Istraživanja su pokazala kako na kliničku ekspresiju migrene utječu prehrambene navike i određeni elementi prehrane. Utvrđeno je nekoliko prehrambenih okidača migrene, što je rezultiralo definiranjem preventivnih strategija kao što su eliminacijske dijete, uravnotežena prehrana te vođenje paralelnih dnevnika prehrane i glavobolje. Prehrambeni okidači migrene koje pacijenti najčešće prijavljuju su gladovanje, alkohol, čokolada i sir. Također, ispituje se učinkovitost određenih dodataka prehrani, poput magnezija, riboflavina, vitamina D, L-karnitina i koenzima Q10, u svrhu ublažavanja simptoma i sprečavanja napada migrene. Primjerice, suplementacija riboflavinom u dozi od 400 mg dnevno tijekom 3 mjeseca rezultirala je smanjenjem napada migrene za 50% u 59% bolesnika. Iako je u literaturi prisutna nedosljednost te nisu postignuti konačni zaključci, dostupni podaci ukazuju na moguće dobrobiti nutritivnih intervencija za pojedine pacijente s migrenom. The frequency of migraines is increasing, but the causes and mechanisms of this disease still remain unclear. Research has shown that the clinical expression of migraine is influenced by eating habits and certain dietary elements. Several dietary triggers of migraine have been identified, resulting in the definition of preventive strategies such as an elimination diet, a balanced diet, and the keeping of parallel diet and headache diaries. The dietary triggers of migraine that patients most often report are starvation, alcohol, chocolate and cheese. Also, the effectiveness of certain dietary supplements, such as magnesium, riboflavin, vitamin D, L-carnitine, and coenzyme Q10, is being examined to alleviate symptoms and prevent migraine attacks. For example, supplementation with riboflavin at a dose of 400 mg daily for 3 months resulted in a 50% reduction in migraine attacks in 59% of patients. Although there is inconsistency in the literature and no definitive conclusions have been reached, the available data suggest possible benefits of nutritional interventions for individual migraine patients.