As one of the largest Phanerozoic orogens in the world, the Central Asian Orogenic Belt ( CAOB) is an excellent place for studying accretionary orogenic process and continental crust growth. It is widely accepted that the CAOB formed by long-lived evolution of the Paleo-Asian Ocean (PAO) from Neoproterozoic to Early Mesozoic, comprises various allochthonous fragments, such as micro continents, island arcs, seamounts/ oceanic plateaus, accretionary prisms, and ophiolitic melanges. The composition of ophiolitic melange is almost same in the western CAOB. Except the typical ophiolite components, the ophiolitic melanges contain pillow basalt, volcanic breccia, reef limestone, olistostrome, and terrestrial elastic rocks. Geochemically, the mafic rocks in ophiolitic melange can be divided into two groups of MORBand OIB-type. The MORB-type belongs to tholeiitic basalt series and shows subduction characteristics; the OIB-type belongs to alkaline basalt series, and is formed in seamount/ oceanic plateau affinity. The age, property and distribution of ophiolitic melanges and metamorphic rocks in the western CAOB indicate that the subduction initiation time of the PAO is no later than Early Neoproterozoic, and the locat ion should be on the southern margin of Siberia plate and gradually develop southward. In the early development of the PAO, the mechanism of subduction initiation should be mantle plume-induced dominant. However, in the later period, the seamount/ oceanic plateau may block the subduction channel, causing the subduction polarity reversal and transition, and the subduction initiation occurs. Initiation of new subduction zone is a difficult problem of Earth's plate tectonics regime. The reason is that the subduction initiation is an extremely short process, scarcity of geological record, and there are few cases of subduction initiation that are happening on Earth today. Therefore, it is necessary for geologists to work together to reveal the past and present lives of the PAO, and to solve the mystery of the subduction initiation of plate tectonics. [ABSTRACT FROM AUTHOR]