1. 开窗减压术与颌骨囊肿刮治术治疗颌骨囊肿的疗效比较 及对术后血清疼痛介质的影响.
- Author
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曾宾华, 陈家财, 罗艳荣, 许志亮, 林晨阳, and 陈玉琳
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NERVE growth factor , *BONE density , *SUBSTANCE P , *NEUROPEPTIDE Y , *POSTOPERATIVE pain , *CURETTAGE , *SURGICAL decompression - Abstract
Objective: To compare the efficacy of fenestration decompression and curettage of jaw cyst in the treatment of jaw cyst and the changes of serum pain mediators after operation. Methods: The clinical data of 60 patients with jaw cyst who were treated in our hospital from January 2016 to August 2019 were analyzed retrospectively. According to the difference of treatment methods, they were divided into group A (curettage of jaw cyst, 28 cases) and group B (fenestration decompression, 32 cases). The operation indexes, postoperative recovery indexes, complications and changes of serum pain mediators in the two groups were observed. Results: Compared with group A, group B had less intraoperative bleeding, shorter operation time and less postoperative pain score. There was significant difference between groups (P<0.05). Compared with group A, group B had higher bone mineral density, thicker hyperosteogeny, larger reduction rate of cyst volume and shorter cyst healing time. There was significant difference between groups(P<0.05). The levels of serum neuropeptide Y (NPY), substance P (SP) and nerve growth factor (NGF) in group B were lower than those in group A at 2 h and 12 h after operation, β Endorphins(β-EP) was higher than that in group A(P<0.05). There was no significant difference in the incidence of complications between the two groups (P>0.05). Conclusions: Compared with curettage for jaw cyst, fenestration decompression has significant advantages, which can reduce intraoperative bleeding, shorten operation time, reduce postoperative pain and promote postoperative recovery. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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