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With the principle of metamorphic mechanism,aiming at the right- angle space problem often encountered in the cabinet arrangement,a new kind of cabinet is designed and the design plan and size calculation are given.

To solve the problems of high labor intensity, poor accuracy, and low mixing uniformity in manually adding cementing and plugging materials, an automated metering and adding device for cementing and plugging materials was developed, mainly consisting of silos, belt metering, and hose spiral conveyors. The device was designed with PLC as the core and touch screen as the human-machine interaction interface. The main hardware includes a level gauge, frequency converter, weighing sensor, and variable frequency motor. The device adopts an expert PID control strategy to achieve signal acquisition, logic control, and data communication. Through automated testing of extreme conveying of fiber materials at 3~5 kg/min and sheet-like materials at 10~50 kg/min, the material can be continuously mixed, stirred, and uniformly and stably delivered at any position through a hose type screw conveyor, meeting the requirements for feeding measurement and conveying of two types of materials, including sheet-like materials and fiber materials, in two silos. The results show that its mixing uniformity is good, with less manual participation, stable measurement accuracy, and an error of less than ± 1%; Compared to manual labor, the overall efficiency is two times higher. The research provides a support for automated operation of offshore oil drilling platforms. [ABSTRACT FROM AUTHOR]

[Objective] This paper focuses on the development of a bidirectional consolidated soil sample-making apparatus. The aim is to compare samples made by this apparatus with those created using compaction and static pressure methods and to analyze and verify the feasibility of the bidirectional properties. [Methods] In this paper, three types of test equipment were used to prepare consolidated soil samples of specified age. Several comparative tests were conducted, such as the unconfined compressive strength (UCS) test, the industrial electron microscopy test, the scanning electron microscopy test, and the mercury-in-pressure porosimetry test. These tests helped analyze and verify the feasibility of the bidirectional consolidated soil sample maker. They also enabled us to study the macro/fine/micro characteristics of the samples produced by the three test equipment from various angles, such as UCS and its destructive form, apparent porosity of the sample, microscopic porosity and filling of the curing product, microscopic pore volume, and pore size distribution. [Results] The results show that in terms of macro UCS of consolidated soil samples, the bidirectional sample has the highest UCS, followed by the static pressure sample and then the compaction sample. In terms of sample formation and destruction form, the bidirectional sample is uniform in color and has a stable destruction form (all are shear destruction). The static pressure sample is denser at the top and looser at the bottom, with destruction mostly in the weaker and lower parts. The compaction sample, however, shows distinct layering with varying shades and multiple forms of damage. Thus, the uniformity of the bidirectional sample is superior to that of the compacted and static compaction samples. Upon fine analysis, we found that compared with the static compaction sample (which has an apparent porosity that gradually increases from top to bottom) and the compaction sample (where the apparent porosity gradually decreases from top to bottom), the bidirectional sample has the smallest and most uniformly distributed apparent porosity. At the microscopic level, the bidirectional sample has the highest amount of curing products that can effectively fill the pores, making its internal microstructure the densest. It also has the least amount of mercury intake and is dominated by interparticle pores with smaller diameters. This is followed by the static pressure sample, while the compaction sample has the least amount of curing products, larger pores, the highest amount of mercury intake, and pores mainly distributed in the interparticle pores with larger diameters and the intragranular pores. [Conclusions] Therefore, the multiscale comparative study shows that the self-developed bidirectional sample-making instrument is better than that of the static pressure instrument outperforms both the static pressure and the three-segment mold (or double membrane) in terms of sample making. Not only does it deliver superior results, but it also exhibits a smaller margin of errors in tests. Consequently, this makes it a viable option for widespread adoption and application in geotechnical tests. [ABSTRACT FROM AUTHOR]

The present research aims to develop a new kind of green composite curing agent, PZ-1 in which the industrial and agricultural waste such as calcium carbide slag and plant ash are adopted to be raw materials, based on the response surface methodology and unconfined compression strength test results. Then, the mechanism of PZ-1 reinforcement of organic sludge was revealed through SEM and XRD analysis. The test results show that with the increase of calcium carbide slag and plant ash content, the unconfined compressive strength of solidified organic sludge shows a phenomenon of first increasing, then decreasing and continuously increasing, respectively, in which the effect of calcium carbide slag on carbide slag is more significant. The optimal ratio of carbide slag and plant ash in PZ-1 is 20:14. Ca (OH)2 in calcium carbide slag will play the role of neutralizing the humic acid existing in the organic silt and further provide the alkaline environment for the stabilization of PZ-1. The main product of stabilized organic silt is C-S-H gel, calcite, dolomite, ettringite, in which C-S-H gel plays the role of producing the structure of stabilized organic silt and the left 3 minerals behave in filling the pore of silt and further enhancing the density of silt. [ABSTRACT FROM AUTHOR]

Aiming at the multi-row facility layout problems with uncertain number and position of vertical passages in rows, a layout optimization model was established with the goals of minimizing logistics intensity, minimizing the no-load intensity of handling equipment and maiming the interrelations between operation units, and a random-key BA was proposed for the model based on mapping rules. The idea of random-key coding was introduced into BA, and the mapping rules and steps from bat position based on random-key coding to combinational solution of multi-row facility layout were defined, so that the algorithm night be executed in continuous spaces without discrerization, and the layout schemes with different code length might be mapped in combinational spaces. Finally, the proposed random-key BA was used to solve an example of multi-row facility layout problem, and the advantages of the algorithm were proved. [ABSTRACT FROM AUTHOR]

Postbiotics are inanimate microbial cells and/or their components as well as microecological preparations made from their metabolites, which are beneficial to the health of the host. Postbiotics can regulate intestinal microbial balance, enhance immunity, and have anti-inflammatory and antibacterial effects. Compared with probiotics, living bacterial cells, postbiotics are safer, and more stable, effective and convenient. This article summarizes the origin, microbial sources, preparation methods and advantages of postbiotics, and elucidates the mechanisms of action of postbiotics in comparison with those of probiotics. In addition, it introduces readers to the applications of postbiotics as functional food supplements, food quality improvers, food preservatives and detoxifying agents in foods. We believe that as the definition, classification, and functional components of postbiotics become clearer, they will be more widely used in the fields of foods, nutraceuticals, foods for special medical purpose, infant foods, and personal care products. The development of postbiotics will also promote the leapfrog development of basic and applied science.

Objective: To evaluate the effect of a novel micro-arc oxidation (MAO) coated magnesium-zinc-calcium (Mg-Zn-Ca) alloy scaffold/autologous bone particles to repair critical size bone defect (CSD) in rabbit and explore the novel scaffold in vivo corrosion resistance and biocompatibility., Methods: Seventy-two New Zealand white rabbits were randomly divided into 3 groups ( n =24), group A was uncoated Mg-Zn-Ca alloy scaffold group, group B was 10 μm MAO coated Mg-Zn-Ca alloy scaffold group, and group C was control group with only autologous bone graft. The animals were operated to obtain bilateral ulnar CSD (15 mm in length) models. The bone fragment was removed and minced into small particles and were filled into the scaffolds of groups A and B. Then, the scaffolds or autologous bone particles were replanted into the defects. The animals were sacrificed at 2, 4, 8, and 12 weeks after surgery (6 rabbits each group). The local subcutaneous pneumatosis was observed and recorded. The ulna defect healing was evaluated by X-ray image and Van Gieson staining. The X-ray images were assessed and scored by Lane-Sandhu criteria. The percentage of the lost volume of the scaffold (ΔV) and corrosion rate (CR) were calculated by the Micro-CT. The Mg 2+ and Ca 2+ concentrations were monitored during experiment and the rabbit liver, brain, kidney, and spleen were obtained to process HE staining at 12 weeks after surgery., Results: The local subcutaneous pneumatosis in group B was less than that in group A at 2, 4, and 8 weeks after surgery, showing significant differences between 2 groups at 2 and 4 weeks after surgery ( P <0.05); and the local subcutaneous pneumatosis was significantly higher in group B than that in group A at 12 weeks after surgery ( P <0.05). The X-ray result showed that the score of group C was significantly higher than those of groups A and B at 4 and 8 weeks after surgery ( P <0.05), and the score of group B was significantly higher than that of group A at 8 weeks ( P <0.05). At 12 weeks after surgery, the scores of groups B and C were significantly higher than that of group A ( P <0.05). Meanwhile, the renew bone moulding of group B was better than that in group A at 12 weeks after surgery. Micro-CT showed that ΔV and CR in group B were significantly lower than those in group A ( P <0.05). Van Gieson staining showed that group B had better biocompatibility and osteanagenesis than group A. The Mg 2+ and Ca 2+ concentrations in serum showed no significant difference between groups during experiments ( P >0.05). And there was no obvious pathological changes in the liver, brain, kidney, and spleen of the 3 groups with HE staining at 12 weeks., Conclusion: The MAO coated Mg-Zn-Ca alloy scaffold/autologous bone particles could be used to repair CSD effectively. At the same time, 10 μm MAO coating can effectively improve the osteanagenesis, corrosion resistance, and biocompatibility of Mg-Zn-Ca alloy scaffold.

Objective: To study the clinical features and diagnosis of 7 patients with atypical mantle cell lymphoma (MCL)., Methods: The 7 MCL patients were misdiagnosed as chronic lymphocytic leukemia (CLL) due to a score of 4 for their immunophenotypes. The clinical features and diagnosis of such patients were retrospectively analyzed., Results: Six patients had superficial lymphadenectasis but their lymph nodes could not be palpated. All 7 patients were as stage IV considering bone marrow infiltration. Scores of immunophenotype of CLL were 4, and interphase fluorescence in situ hybridization (FISH) for t(11;14) were positive in all patients., Conclusion: Some MCL patients have clinical features similar to CLL. Interphase FISH can play an important role in the diagnosis of MCL.

Objective: To investigate the prevalence and risk factors of mild vision loss in adult patients with type 2 diabetes in Beixinjing Community, Shanghai, China., Methods: A population-based, cross-sectional survey among 2 216 Chinese Han adult patients with type 2 diabetes was conducted from October 2014 to January 2015.Random cluster sampling was used to enroll diabetic patients based on the local Chronic Diseases Prevention and Control System data.The survey was preceded by a pilot study in which operational methods were refined and quality assurance evaluation was carried out.Eligible participants underwent a comprehensive eye examination, including the best corrected visual acuity (BCVA) test using the logarithm of the minimum angle resolution charts.Mild vision loss was defined as BCVA <20/32 to ≥20/63 following the International Council of Ophthalmology (ICO) 2002 definitions.The primary causes of visual impairment and blindness were determined.The prevalence and causes of monocular and binocular mild vision loss were investigated.Logistic regression analysis was used to determine the related risk factors of binocular mild vision loss., Results: Among 2 582 patients, 2 216 were examined, and the response rate was 85.8%.Monocular mild vision loss was found in 591 patients with a prevalence rate of 26.7%.Binocular mild vision loss was detected in 650 patients, with a prevalence rate of 29.3%.Totally 1 891 eyes were confirmed as mild vision loss.Diabetic retinopathy (27.3%, 517/1 891) were the second leading cause of mild vision loss, after cataract (31.3%, 591/1 891). Binocular mild vision loss of unknown reasons happened in 201 persons.Old age, female gender, lower educational level, higher glycosylated hemoglobin A1c level and longer duration of diabetes were associated with the prevalence of total binocular mild vision loss and binocular mild vision loss of unknown reasons., Conclusion: The prevalence of mild vision loss is higher among adult patients with type 2 diabetes in Beixinjing Community.Intensive glucose control is recommended to prevent and slow mild vision loss in Chinese Han patients with type 2 diabetes.

Objective: To report a case of primary cardiac plasmablastic lymphoma to investigate its clinical feature, diagnosis, therapy and prognosis., Methods: A case of primary cardiac plasmablastic lymphoma was studied. The imaging examination, conventional histopathological and immunohistochemical staining of this case were detected. The clinical feature, pathogenesis, diagnosis, therapy and prognosis of primary cardiac plasmablastic lymphoma were further investigated through literatures review., Results: The tumor was located in the right atrium. Microscopic examination showed diffuse proliferation of large lymphoid cells. The neoplastic cells were positive for CD38 and CD79a. The patient was treated with chemotherapy combined with autologous stem cell transplantation., Conclusion: Primary cardiac plasmablastic lymphoma was extremely rare. Its pathogenesis remained to be unclear. With non- specific clinical manifestations, the diagnosis was mainly confirmed by histopathological and immunohistochemical staining method. Without standard treatment, more patients were treated with chemithreapy regimens similar to the treatment used in aggressine lymphoma. Patients usually had a poor prognosis.

Objective: To investigate the status of eye disease prevention resources in community health service centers, to understand the distribution of ophthalmology service resources in each community, and to understand the main problems existing in the work of blindness prevention and treatment in Shanghai, so as to strengthen the prevention of blindness and improve the primary eye care level., Methods: Using the survey method, we carried out the investigation of disease control and prevention resources in all community health service centers to obtain the data of eye disease prevention and treatment resources. Using the descriptive statistics, we described the distribution of resources of eye disease prevention and treatment in different districts., Results: There were 244 communities in 17 districts and counties in Shanghai, of which 236 (96.72%) communities participated in the survey and completed the questionnaires. Forty-nine (20.8%) communities had independent outpatient departments of ophthalmology, 96 (40.7%) had departments of ophthalmology and otorhinolaryngology, 33 (14%) had ophthalmology doctor visits from secondary or tertiary medical institutions, and 87 (36.9%) had no outpatient department of ophthalmology. There were 82 oculists, 129 general or otorhinolaryngology doctors treating eye disease, 9 ophthalmic nurses, and 1 optometrist. There were 36 specialized personnel for public health of eye protection and 217 part-time personnel. Moreover, there were a total of 1 103 pieces of ophthalmic equipment in all communities with the use rate of 91%., Conclusions: Uneven ophthalmology resources and eye care professional ability in community health service centers, lack of technical and public health personnel for prevention of eye disease, backward eye disease screening equipment, and inadequate investment in prevention and treatment of eye disease are major problems. More government supports for prevention and treatment of eye disease in communities and continuous improvement in three-level blindness prevention network systems and information construction are needed.

Objective: To investigate clinical features, diagnosis, therapy, and prognosis in a case of chronic lymphocytic leukemia (CLL) with central nervous system (CNS) invasion., Methods: The cellular morphology of bone marrow, cytology and flow cytometry of cells in CSF, and radiographic manifestations were detected in a patient diagnosed as CLL with CNS invasion. The clinical features, pathogenesis, diagnosis,therapy, and prognosis of CLL with CNS invasion were reviewed by literatures., Results: A clonal population of B lymphocytes with typical characteristics of immunophenotype was identified in the patient. After treated with intrathecal chemotherapy, the patient returned to normal cells count of cerebrospinal fluid and normal neurologic status. Previous studies also have demonstrated the efficacy of intrathecal chemotherapy., Conclusion: CNS invasion is a rare complication of CLL. Early detection and treatment may result in better outcomes.

Objective: To evaluate the impact of amplitude of accommodation on controlling the development of myopia in orthokeratology., Methods: Forty-nine children aged 7 to 14 years were enrolled in this prospective clinical study.Orthokeratology was performed to correct the refractive errors of these children after measurement of refraction, corneal topography, amplitude of accommodation and axial length. Axial length (AL) and amplitude of accommodation was measured after treatment. The average amplitude of accommodation was calculated and was used as the cutting point for dividing the cohort into "amplitude of accommodation above average" vs. "amplitude of accommodation below average". Data were analyzed by paired t-test, independent t-test, repeated measures-ANOVAs and Pearson correlation analysis., Results: The AL before and after 1- year and 2-year treatment was (24.98 ± 0.75) mm, (25.13 ± 0.74) mm and (25.32 ± 0.78) mm, respectively. AL increased significantly throughout the observed 24-month period (F = 75.848, P < 0.001) . Amplitude of accommodation increased from (13.68 ± 2.65) D to (16.12 ± 2.41) D in 2 years (t = -6.461, P < 0.001) and amplitude of accommodation significantly affected axial growth (F = 7.395, P = 0.009) . The axial growth of subjects with below average amplitude of accommodation and those with above average amplitude of accommodation was (0.23 ± 0.25) and (0.44 ± 0.30) mm, indicating a statistically difference(t = -2.719, P = 0.009). AL change in subjects with below average amplitude of accommodation was 55.81% that of the subjects with above average amplitude of accommodation. Baseline amplitude of accommodation was positively correlated to axial growth at 24-month visit (r = 0.502, P < 0.001). Linear regression analysis was used between baseline amplitude of accommodation and 2-year axial growth: Axial growth = 0.055· Baseline amplitude of accommodation-0.409(F = 15.806, P < 0.001). The change of amplitude of accommodation for subjects with below average amplitude of accommodation and those with above average amplitude of accommodation after 2-year was (4.04 ± 2.16) D and (0.91 ± 2.15) D, indicating statistically difference (t = 5.084, P < 0.001)., Conclusions: Myopic control effect would be more beneficial to lower amplitude of accommodation children than that to higher amplitude of accommodation children in orthokeratology. The enhancement of accommodation provides some basis for slowing myopia progression with orthokeratology.

In this paper, a new method was presented which can generate dental panoramic radiographs from the 3D CT sectional data. The dental panoramic radiograph was generated by casting ray into the 3D sectional data from a curved surface close to the dental arch. With this method, the relationship between the 3D CT sectional data and the dental panoramic radiographs was built, which helped to overcome the defects in the real X-ray panoramic radiographs, such as structure overlap and unselectable content for displaying. The technology is of certain significance in computer aided technique and surgical planning related to dentistry.

Objective: To evaluate the effect of different factors on the prognosis of rhegmatogenous retinal detachment (RRD) associated with choroidal detachment (ChD)., Methods: One hundred and eighty-eight eyes of 188 patients were studied retrospectively from Jan, 1996 to Aug, 1998. The clinical data, surgical management and follow-up records were analyzed., Results: The total successful rate of the surgery was 83.0%, lower than that of general RRD. In the eyes with proliferative vitreoretinopathy (PVR) A-B, the rate was 89.6%, in the eyes with C(1)-C(3) PVR, the rate was 84.1%, in D(1)-D(3), 69.0%. In eyes with severe PVR the successful rate of vitrectomy was higher than that of scleral buckling alone. Administration of steroids before surgery resulted in high successful rate, but the length of time of the steroid treatment had no effect on the successful rate. In the eyes using scleral buckling alone, the drainage or without the drainage of subretinal fluid had no effect on the successful rate., Conclusions: RRD associated with ChD has worse prognosis than general RRD. The administration of steroids before surgery is necessary, and the timing of surgery is also important. In eyes with light PVR and ChD, scleral buckling without drainage of subretinal fluid is the first choice, but in eyes with severe PVR and ChD, vitrectomy is a better choice.