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Objective Faults are among the most prevalent geological structures in oil and gas basins. Because of their significant connection to oil and gas resources, they have consistently attracted the attention of experts and scholars in the field, making them a hot research topic. Although previous researchers delved tirelessly into the correlation between faults, oil, and gas, new theoretical breakthroughs have been steadily emerging and have been used to promote advancements in oil and gas exploration. Nonetheless, there continues to be a dearth of thorough investigations into the underlying links between faults and the formation and distribution of oil and gas reservoirs, as well as methods for comprehensively and quantitatively defining the connections between faults and oil and gas. Methods The formation of a fault from inception encompasses multiple stages of development, including implicit and explicit stages, and differentiating the diverse growth stages of a fault, ranging from the initial embryonic stage to the terminal stage, poses a significant challenge. To address this issue, the Dongying Sag in the Bohai Bay Basin was selected as the focal point of this study. By employing physical and numerical simulation techniques, the researchers sought to replicate the entire life cycle evolution of the Chennan Fault, a basin-controlling boundary fault, from its embryonic stage to its terminal stage while elucidating the distinct characteristics of each stage. Building upon this foundation, the relative ages of the primary faults in the Dongying Depression and the various modes of fault activity at different stages were qualitatively and quantitatively determined, leading to the establishment of a reservoir-control model. Results The research findings indicate that normal faults tend to grow in six distinct stages: the embryonic stage (0 < RA (relative age) ≤ 1), characterized by microfractures or induced fracture zones; juvenile stage (1 < RA ≤ 2), with an intermittent connection of fault geometry; mature stage (2 < RA ≤ 3), marked by the connection of plate-like fault geometry and clear fault throw; declining stage (3 < RA ≤ 4), in which induced fracture zones form on both sides of the fault core, resulting in a shovel-like fault geometry; terminal stage (4 < RA ≤ 5), ramp-flat fault geometry, which has complex derived structures; and death stage (5 < RA ≤ 6), in which fault movement stops or undergoes inversion. The activity pattern of a fault is intricately linked to the duration and intensity of its age. Stable continuous, and high-intensity fault activity promotes the evolution of faults into their terminal stage. Research on reservoir control traps indicates that faults can create reservoirs at all stages of their development. However, as faults age, their ability to control reservoir formation strengthens. The types of traps influenced by faults transition from individual, isolated structures to a variety of arrangements. Moreover, the diversity of oil and gas reservoirs evolves from singular to multifaceted, and the size of these reservoirs expands from small to large. The embryonic and juvenile stage faults primarily influence closure; the mature stage faults predominantly impact sand and reservoir; and the declining stage and terminal stage faults primarily govern the overall distribution range of source rocks, as well as the migration, accumulation, and dissipation of oil and gas. Conclusion The reservoir control potential of the Chennan Fault was assessed by considering factors such as reservoir control advantages, the degree of oil and gas enrichment, and the scale of oil and gas accumulation. The reservoir control capacity of the Chennan Fault was classified as “strong.” Reevaluation of the fault’s reservoir control potential from the perspective of its developmental and evolutionary stages significantly enhances and elevates theoretical research on fault reservoir control and also advances exploration efforts in established mature areas. [Significance] Identifying the formation age and evolutionary patterns of extensional faults has immense theoretical and practical importance for comprehending alterations in the fault’s reservoir control capabilities. Moreover, it offers crucial guidance for oil and gas exploration, particularly for enhancing the reserves in existing exploration areas.

Objective To analyze the clinical effect of flexible fiber splint on traumatized permanent teeth with horizontal root fractures and to provide the basis for clinical treatment. Methods The case data of 54 permanent root anterior teeth with horizontal root fractures were collected. Patients with affected teeth were followed for 1 to 2 years to analyze the root fractures. The preservation rate and pulp survival rate were analyzed, and further analysis was performed on the effects of the root fracture location (cervical 1/3, Mid-root, apical 1/3), root development stage (mature permanent teeth, young permanent teeth), dislocation of the coronal fragment ( 1 mm) on root fracture healing and dental pulp survival. Results A total of 54 teeth with root fractures were treated according to the International Dental Trauma Association Treatment Guidelines. After the application of flexible fiber splint fixation, the tooth preservation rate was 90.7%, and the pulp survival rate was 75.9%, the hard tissues healing rate was 61.1%(33/54). There were no significant differences in the locations of root fractures, the developmental stages of the roots, or the degrees of dislocation of coronal fragment on the types of root fracture healing or dental pulp survival (P > 0.05). Conclusion The flexible fiber splint has a wide range of indications. Except for affected teeth with the root fracture located above the alveolar crest, other types of horizontal root fractures in anterior teeth can be treated with flexible fiber splint fixation and can achieve a good prognosis.

Taking the digitized description and grade classification of the handling comfort of vehicle gear shift level as study object, with operation intensity and perception intensity as the indicators for measuring human comfort from the angles of physiology and psychology respectively, the mathematical relationship between operating force versus operation intensity and perception intensity in operation process is determined, and according to which, a vector description of handling comfort based on Euclidean distance is proposed. With these comfort vec- tor point set as sample data, a recognition/classification is conducted by using fuzzy C-means cluster analysis to obtain handling comfort grade in different ranges and hence fulfill the grade classification for the handling comfort of gear shift level. [ABSTRACT FROM AUTHOR]

Objective: To study the change of inflammatory factors at different stages of colorectal cancer (CRC)., Methods: Thirty normal subjects, 30 patients with colorectal adenomatous polyps and 120 CRC patients at different stages were enrolled. IgG, IgM, and IgA levels, the inflammatory cytokines IL-2, 4, 6, 10, and 12 and the expression of TGF-β 1 and VEGF in the serum were analyzed by ELISA or immunoturbidimetry., Results: The serum concentrations of IL-12, TGF-β 1, and IL-6 in the CRC patients were statistically different compared with the normal and adenomatous polyps, and increased as the disease progressed (P<0.05). IL-6 reached the highest level in C phase of CRC.The serum concentrations of IL-2, IL-4, and IL-10 were significantly different among the groups. VEGF serum levels in CRC Phase A and Phase B compared with other groups were statistically different, but other serum concentrations had no significant difference (P>0.05). The serum level of IgG, IgM, and IgA in the 3 groups showed no significant difference (P>0.05)., Conclusion: The serum level of inflammatory cytokines TGF-β 1, IL-6, and IL-12 increases gradually with the development of CRC, which may change the microcirculation of patients with CRC, and promote the development of CRC.

Objective: To explore the effects of different feeds, including rice, flour and the compound coarse grain on the disordered lipid metabolism in rats., Methods: 40 male SD rats were divided into 4 groups, including the negative control group, the hyperlipemic control group, the rice-flour group and the compound coarse grain group. All 4 group rats were given different feeds for 10 weeks, body weights were weighted, serum TC, TG and HDL-C contents were determined and liver pathology were observed., Results: When compared with the negative control group, the disordered lipid metabolism model was successfully made in hyperlipemic control group. When compared with the hyperlipemic control group, the serum TG and TC contents significantly declined and HDL-C significantly increased in the compound coarse grain group. Moreover, the conditions of liver cell fatty degeneration in compound coarse grain group were slight., Conclusion: Compound coarse grain could improve the lipid metabolism in rats.