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Coal mining engineering involves complex stress structure time effect issues, which are closely related to the occurrence and prevention of rock burst disasters. Therefore, this study conducts experimental research on the stress structure time effect of impact coal. Coal rock specimens were obtained from three coal mines in Shaanxi, Gansu, and Inner Mongolia. The stress-time effect of loading rate was studied through coal uniaxial compression static-dynamic load and creep tests. The stress-time effect under the condition of coal in situ release was investigated using a long-term segmented test method. Water immersion tests on coal and structural time-effect studies on coal-rock combinations were conducted. The experimental results indicate that there is a positive correlation between the uniaxial compressive strength of coal and the loading rate, and a negative correlation with the duration of in-situ relief and immersion time. The combined mode of coal-rock structure time effect significantly affects its energy and strength properties, while impact coal exhibits both stress and structural time effects. According to the experimental results, a plastic limit structure is proposed to explain the irreversible deformation of coal-rock mass under stress. Furthermore, by constructing a time-dependent model for plastic strain in coal under impact conditions and comparing the numerical approximations of non-elastic strain and irreversible strain, the plastic limit strain characteristics of shock-induced coal were verified.

Collaborative encirclement of multiple unmanned ground vehicles (UGVs) is a focal challenge in the realm of multiagent collaborative tasks, representing a fundamental issue in complex undertakings such as multiagent collaborative search and interception. Although optimization algorithms have yielded rich research outcomes in collaborative encirclement, challenges persist, including poor real-time computational efficiency and weak robustness. Reinforcement learning theory holds considerable promise for addressing multiagent sequential decision problems. This paper delves into the study of the collaborative encirclement of multiple UGVs based on deep reinforcement learning theory, focusing on the following key aspects: establishing a kinematic model for UGVs to describe the collaborative encirclement task, detailing the collaborative encirclement process, developing strategies for target UGV escape, and addressing challenges arising from the increasing number of UGVs, which results in a complex environment and issues such as algorithmic instability, dimension explosion, and poor convergence. This paper introduces a collaborative encirclement algorithm based on the soft actor–critic (SAC) framework. To address issues related to poor collaboration and weak generalization among multiple UGVs, long short-term memory is incorporated into the network structure, serving as a memory function for UGVs. This tactic aids in capturing and using information from historical observation sequences, effectively processing time–series data, making more accurate decisions, promoting mutual collaboration among UGVs, and enhancing system stability. To tackle the issue of increased state space dimensions and low training efficiency during collaborative encirclement, an attention mechanism is introduced to calculate and select attention weights in the state space, focusing attention on key states relevant to the task. This strategy helps constrain state space dimensions, ensuring network stability, achieving stable and efficient collaboration among multiple UGVs, and improving algorithm training efficiency. To address the problem of sparse rewards in collaborative encirclement tasks, a mixed reward function is proposed that divides the reward function into individual and collaborative rewards. Individual rewards guide UGVs toward the target, incentivizing their motion behavior, whereas collaborative rewards motivate a group of UGVs to collectively accomplish the encirclement task. This approach further guides UGVs to obtain more frequent reward signals, ultimately enhancing the algorithm convergence speed. Simulation and experimental results demonstrate that the proposed method achieves faster convergence than SAC, with a 15.1% reduction in encirclement time and a 7.6% improvement in success rate. Finally, the improved algorithm developed in this paper is deployed on a UGV platform, and real-world experiments in typical encirclement scenarios validate its feasibility and effectiveness in embedded systems.

Objective Aiming at the insufficient control indexes for high-speed railway subgrade horizontal deformation currently, it is necessary to study the influence law and limit values of ballastless track subgrade horizontal deformation. Method Using finite element method, the structural stress, deformation, and track irregularity of CRTS (China railway track system) II type ballastless track are calculated under horizontal deformation conditions of cosine-shaped subgrade with different wavelengths and amplitudes. Referring to the allowable tolerance values for track geometric dimensions and the allowable tensile stress values of ballastless track structure, the transmission law and limit values of subgrade cosine-shaped horizontal deformation are studied. Result & Conclusion The horizontal deformation of ballastless track structures such as rail, track slab, mortar layer and supporting layer shows significant response characteristics to cosine-shaped horizontal deformation of high-speed railway subgrade. When the wavelength and amplitude of horizontal deformation are 20 m and 10 mm respectively, the influence of subgrade cosine-shaped horizontal deformation on track alignment irregularity is the greatest, followed by the influence on track horizontal irregularity, while the influence on gauge and vertical irregularity indicators can be ignored. When the amplitude of horizontal deformation is 20 mm, as its wavelength increases, the maximum value of rail horizontal deformation increases, while the track irregularity, track slab and supporting layer tensile stresses first increase and then decrease. The limit value of subgrade cosine-shaped horizontal deformation amplitude increases with the increase of horizontal deformation wavelength, and the two satisfy a quadratic function relationship.

With the continuous development and maturity of critical care medicine, the problem of hospital acquired infection(HAI) in the department of critical care medicine has become increasingly prominent. HAI can cause serious adverse consequences, therefore, clarifying its key links and pathogenesis, and exploring more reasonable and effective systematic prevention and control measures are of great significance for reducing HAI in the department of critical care medicine. In addition to systematic prevention and control measures, multidisciplinary collaboration, strong support from administrative departments, and strict implementation of the specific details of HAI prevention and control are also indispensable for properly solving this intractable problem.

In this study, the synergistic effect of Quillaja saponin (QS) and soybean protein isolate (SPI) on stabilizing emulsion gels was used to prepare plant-based mayonnaise (PM) with high protein content and reduced fat content. Comparative characterization of PM and two commercially mayonnaises in terms of appearance, droplet size, texture, rheological properties, thermal and freeze-thaw stability was conducted by static light scattering, laser confocal scanning microscopy (LCSM), small deformation rheology and texture profile analysis (TPA). It was found that high-protein and fat-reduced MP (10% SPI and 50% fat or 11% SPI and 40% fat, m/m) which was compared to commercial mayonnaises in terms of appearance, spreadability, texture and rheological properties was made using 10% SPI and 0.18% QS or 10% SPI, 0.18% QS and 1% SPI gel particles (SGPs) as protein ingredients. In the systems, QS not only endowed a viscosity-thinning texture modifier to protein-rich emulsion products, but also imparted superior thermal stability and freeze-thaw stability to SPI-based emulsion gels. These findings will provide theoretical and technical guidance for the development and application of high-protein and fat-reduced plant-based mayonnaise.

For boiling water reactors and small reactors, an effective way to reduce containment pressure is to discharge gas from the containment into the suppression pool. Based on the above background, a series of experiments were conducted to investigate the pressure oscillations frequency of steam-air gas discharged into a supercooled water pool. The air mass fraction was 0.0-0.4, and the hole pitch was 1.5d-3d. The air compressor and electric boiler generated air and steam, respectively. The steam and air were mixed and discharged into the supercooled water pool. A high-frequency dynamic pressure sensor was used at the nozzle outlet to record the pressure oscillation signal, and a high-speed camera captures jet plume images. The fast Fourier transform (FFT) was used to process the pressure signal, and the peak value of the frequency domain signal is the dominant frequency of the oscillation. The image observation reveals that in the case of a double-hole jet, the interference of the two gas plumes causes the gas plumes to converge or even agglomerate to form a combined jet. The dominant frequency of the double-hole jet is lower than that of the single-hole jet because of the increase in the dimension of the double-hole jet plume, which leads to a longer condensation time. Therefore, increasing the number of holes will result in a decrease in the dominant frequency of the oscillation, which may be closer to the equipment's natural frequency and lead to resonance damage. For temperature effects, the condensation time of the plume is shorter as the subcooling increases, so the oscillation frequency increases with subcooling. For the effect of hole pitch, the dominant frequency increases with hole pitch. The water temperature between the two gas plumes decreases as the hole pitch increases, and the gas plumes condense faster and take less time to condense. Based on the research conclusions of the dominant frequency characteristics of the steam jet condensation, an empirical equation for predicting the dominant frequency was proposed, and the predicted deviation is within the range of -15%-20%. The oscillation dominant frequency of the steam-air mixture jet increases with the subcooling degree and the hole pitch, which is consistent with the conclusion of the steam jet. When steam-air mixture gas jets, the dominant frequency is inversely proportional to the non-condensable gas mass fraction. The reason is that during the steam-air mixture gas jets, the concentration of non-condensable gas increases after steam condensation between the gas-water interfaces, which inhibits the mass transfer process, resulting in a longer condensation time. As the fraction of non-condensable gases increases, the mass transfer inhibition becomes more pronounced.

BackgroundThe unfolding-synthesis technique is commonly used in digital pulse processing systems for nuclear radiation measurements.PurposeThis study aims to propose a novel flat-topped widened peak-shaping algorithm based on the pulse unfolding-synthesis technique is proposed.MethodsFirstly, the repetition and polynomials were utilizes to shape the digital pulses, and the nuclear pulse signal was unfolded into unit pulses series. Then, an impulse response system was employed to synthesize these unit pulses series to achieve the desired peak shape. Finally, the improved flat-topped peak-shaping algorithm was compared and analyzed against traditional filter shaping algorithms in terms of accuracy in amplitude extraction, interference resistance, and pile-up recognition.ResultsExperimental results demonstrate that, under the same shaping time, the energy resolution of the flat-topped peak-shaping algorithm for the γ characteristic peak of 137Cs is 7.2%, outperforming the trapezoidal, triangular, and Gaussian shaping algorithms. Additionally, it exhibits high counting rate performance.ConclusionsThe flat-topped peak-shaping algorithm of this study can effectively replace traditional pulse-shaping methods and be utilized for high-precision, high-count-rate γ spectroscopy measurements.

The 1∶500000 seismotectonic map of the Ordos active block and boundary zone is a special achievement of the national key research and development project “Research on dynamic model and strong earthquake risk of Ordos active block boundary zone” . Taking the Ordos active block and boundary zone as the mapping scope, this map refers to the compilation standards and database standards of seismotectonic map in the seismic industry, and carries out high-resolution image interpretation on the basis of systematically collecting and collating geographic information, geology, active tectonics, earthquake, geophysics and other data. It absorbs the latest research results of the project and builds the basic database required for mapping. Through data vectorization, stratigraphic boundary modification, fault modification, map modification, the 1∶500000 seismotectonic map of the Ordos active block and boundary zone was compiled. This map reflects the boundary zone of Ordos active blocks such as Yinchuan Basin Helan Mountains, arc structure bundle, Weihe Basin, Shanxi graben system, Hetao Basin and the seismic structure of adjacent blocks, the geometric and kinematic images of active tectonics in the Ordos block and boundary zone were improved.

To determine the impact of high-temperature-induced thermal damage on the acoustic emission characteristics and fracture mechanism of granite during various stress stages, uniaxial compression tests and real-time acoustic emission monitoring of thermally damaged granite at 25, 200, 400, and 600 ℃ were performed. The peak frequencies of thermally damaged granites, the distribution characteristics of RA-AF (AE rise time/AE amplitude-AE average frequency) data, and the distribution patterns of energy concentration \begin{document}$\rho $\end{document} at various loading stages were investigated. The results show that the stress stages of granite under uniaxial compression conditions after thermal damage at each temperature can be divided into the following stages: Stage Ⅰ corresponds to the crack compaction stage; Stage Ⅱ corresponds to the crack emergence and stable development stage; Stage Ⅲ corresponds to the crack unstable development stage; and Stage Ⅳ corresponds to the post-peak damage stage based on the acoustic emission development characteristics. Further, the more severe the thermal damage to the granite, the earlier the granite enters Stage II and the longer the duration of this stage. The acoustic emission peak frequency of thermally damaged granite at different temperatures exhibits a band distribution across four principal frequency regions. With increasing severity of thermal damage, the generation of medium- and high-frequency fracture signals occurs earlier, resulting in a wider distribution range of the primary frequency bands. In addition, there is a decrease in the occurrence of ultrahigh frequency signals during the failure stage. The distribution characteristics of the acoustic emission RA-AF data of the thermally damaged granite at different temperatures can provide insights into the cracking mechanism observed during different stress stages. Subsequently, Stage I generates a small amount of tensile and tension–shear cracks; Stage II generates mixed tension–shear cracks; Stage III generates tensile and mixed tension–shear cracks while shear cracks continue to develop and enlarge; and Stage IV generates numerous shear cracks. The thermally damaged granite is more likely to produce shear cracks under pressure. The higher the temperature of thermal damage, the more shear cracks develop. The curve of energy concentration based on acoustic emission data during uniaxial compression of granite contains three major stages: the initial irregular fluctuation, stable, and abrupt drop stages, which have obvious correspondence to stages I, II, and III, respectively. The abrupt change point between the stable and abrupt drop stages of the energy concentration curve can be used as a failure precursor for granite samples under uniaxial compression.

ObjectiveThis study aimed to establish a quantitative 3-plex droplet digital polymerase chain reaction （ddPCR） method for simultaneously detecting the copy numbers of Salmonella， Bacillus cereus， and Listeria monocytogenes in instant food.MethodsThree pairs of primers and probes corresponding to three single-copy-genes were selected as target genes. The genes were the essC gene in Bacillus cereus， ttrA/ttrC gene in Salmonella， and invasion-associated endopeptidase gene in Listeria monocytogenes. The specificity of the primers and probes were verified by real-time fluorescence quantitative PCR separately. A 3-plex ddPCR method was constructed to detect the copy numbers of three pathogenic bacteria simultaneously.ResultsThe linear ranges were： 25-22 687 copies/20 µL for Salmonella， 19-15 620 copies/20 µL for Bacillus cereus， and 18-23 373 copies/20 µL for Listeria monocytogenes. The three linear correlation coefficients were r≥0.999. relative standard deviation （RSD）≤12% at six concentrations and repeated thrice， indicating favorable repeatability. The minimum detection limits were six copies/20 µL for Salmonella， three copies/20 µL for Bacillus cereus， and seven copies/20 µL for Listeria monocytogenes. When a simulated sample of contaminated rice noodles was detected by 3-plex ddPCR and the plate counting method， the deviation between these two methods was

The high integration of the civil aircraft avionics systems will lead to an exponential rise in the size of airborne safety-critical software, and cause the numerous and inconsistent sources of its requirements, the transfer of requirements at each level of the avionics system software has duality and other problems. Therefore, how to ensure the consistency of the avionics software has become one of the core issues to be solved during the development of the system. On the basis of the syntax of Safety_SysML state machine, the Safety_SysML consistency verifier is designed, including static data detection and dynamic data detection. The test cases are designed for unit and integration test of the core algorithm and system. Based on the error inference and boundaries, the functional tests are designed and executed to find the defects in the verifier. The results show that the Safety_SysML consistency verifier can effectively identify the problem of duality in avionics system software, and is of significant importance for improving the reliability of the avionics software.

The software development process encounters several challenges due to the increasingly functional, complex, expensive, and condensed development cycles of civil aircraft avionics systems, including inaccurate requirements, overly coupled architecture design, and difficult tracing of process outputs. Based on the research of advanced technologies and methods, such as digital development, process development, continuous integration,cloud development environments, a solution is proposed for software development issues in complex civil aircraft avionics systems. In this paper, it is demonstrated how the solution for civil aviation software development is used in the process of developing avionics systems software. The viability of the complex avionics system software development and management method for civil aircraft proposed are also demonstrated. To increase the effectiveness and caliber of software development, the method has been used in the development of the C919 civil aircraft display system.

To overcome the limitations of the oral limitations of capsaicin, this study prepared a thiolated chitosan-zein nanoparticle delivery system loaded with capsaicin. The preparation process was optimized based on particle size and loading capacity, and the efficiency of encapsulation was verified by fluorescence spectroscopy, Fourier transform infrared (FTIR) spectroscopy, and transmission electron microscopy (TEM). The stability and release properties of the capsaicin-loaded nanoparticles were also evaluated during in vitro digestion. The results showed that at a thiolated chitosan to zein to capsaicin of 10:10:1, the particle size of the nanoparticles, which were observed to be regular spherical in shape, was (76.05 ± 1.06) nm, and the loading capacity was (36.85 ± 1.22) μg/mg. The nanoparticles were formed through hydrogen bonds and hydrophobic interactions. In addition, the nanoparticles had good pH stability and ionic strength stability, which could effectively delay the release of capsaicin during simulated digestion in vitro, and the release ratio after 4 h digestion was only (40.08 ± 4.28)%. The nanoparticles can be used for oral delivery of capsaicin.

Objective To investigate the effect of music therapy combined with psychological counseling on negative emotion and quality of life in patients with chronic obstructive pulmonary disease (COPD). Methods Totally 120 COPD patients were randomly divided into the observation group and the control group, with 60 cases in each group. All patients were given routine drug treatment including drugs acting on relieving cough and reducing sputum, bronchodilator, glucocorticoids, anti-Infective agents and drugs given by oral inhalation. Patients in the observation group received music therapy combined with psychological counseling. After discharge, regular telephone follow-up visits were used to urge them to adhere to music therapy and psychological counseling. Hamilton Depression Scale (HAMD) and Hamilton Anxiety Scale (HAMA) were used to evaluate the depression and anxiety status of patients, and COPD assessment test (CAT) and quality of life assessment scale (QOLAS) were used to evaluate the quality of life of patients. The relevant data between the two groups were compared before and after a twelve-week course of therapy. Results After 12 weeks of intervention, HAMD score ［(10. 44 ± 0. 58) vs. (12. 26 ± 2. 06), t＝ 6. 587, P＜0. 001］, HAMA score ［(8. 54 ± 2. 24) vs. (11. 55 ± 1. 78), t ＝ 8. 149, P＜0. 01］, CAT score ［(14. 32 ± 5. 13) vs. (18. 77 ± 6. 95), t＝3. 990, P＜0. 01］ and QOLAS score ［physiological domain (125. 33 ± 4. 87) score vs. (113. 22 ± 5. 12) score, t = -13. 275, P＜0. 01; psychological domain (110. 42 ± 4. 16) score vs. (98. 44 ± 4. 78) score, t = -14. 644, P＜0. 01; social relationship domain (75. 38 ± 4. 03) score vs. (68. 55 ± 3. 46) score, t = -9. 960, P＜0. 01; environmental domain (98. 73 ± 4. 57) score vs. (92. 75 ± 4. 38) score, t = 7. 318, P＜0. 01］ of the observation group were significantly different from those of the control group. Conclusion Music therapy combined with psychological counseling can relieve the negative emotions of depression and anxiety in COPD patients, and can effectively improve their quality of life. (目的 探讨商调音乐联合心理疏导对慢性阻塞性肺疾病(COPD)患者抑郁、焦虑状态及生活质量的影响。方法 采用前瞻性研究方法, 选取2019年1月—2020年7月呼吸中心住院的COPD患者, 按数字随机法分为观察组和对照组, 各60例。两组均给予常规药物治疗, 包括止咳化痰药、支气管舒张剂、糖皮质激素等, 若合并感染给予抗感染药物, 经治疗病情改善出院后序贯吸入性及口服性药物。观察组在此基础上给予商调音乐联合心理疏导, 出院后采用定期电话回访方式督促其坚持音乐疗法及进行心理疏导。采用汉密尔顿抑郁量表-17项(HAMD)、汉密尔顿焦虑量表(HAMA)来评价患者抑郁及焦虑状态, 同时采用慢性阻塞性肺病评估测试(CAT)及生活质量评估量表 (QOLAS)来评价患者的生活质量。干预12周为1个疗程, 干预前后比较两组间相关数据。结果 干预12周后, 观察组与对照组HAMD评分［(10. 44±0. 58)分 vs. (12. 26±2. 06)分, t＝6. 587, P＜0. 01］、HAMA评分［(8. 54±2. 24)分 vs. (11. 55±1. 78)分, t＝8. 149, P＜0. 01］、CAT评分［(14. 32±5. 13)分 vs. (18. 77±6. 95)分, t＝3. 990, P＜0. 01］、QOLAS评分［生理领域: (125. 33±4. 87)分 vs. (113. 22±5. 12)分, t＝-13. 275, P＜0. 01; 心理领域: (110. 42±4. 16)分 vs. (98. 44±4. 78)分, t＝-14. 644, P＜0. 01; 社会关系领域: (75. 38±4. 03)分 vs. (68. 55±3. 46)分, t＝-9. 960, P＜0. 01; 环境领域: (98. 73±4. 57)分 vs. (92. 75±4. 38)分, t＝7. 318, P＜0. 01］比较, 差异有统计学差异。结论 商调音乐联合心理疏导能减轻COPD患者抑郁及焦虑负面情绪, 有效提高其生活质量, 值得临床借鉴。)

Individual tactical assessment is a comprehensive reflection of intelligence, skills and physical fitness. Currently, the training sites and equipment commonly used in tactical training vary widely, lacking necessary norms and standards. Based on image recognition and photoelectric detection technique was used to implement the intelligent design individual tactics training evaluation system, the system is mainly used for photoelectric sensor instead of traditional barbed wire to training more enter, leave, jump, sprint training. In order to judge whether the time for the trainer to pass through all the shelters and whether the movement essentials are standard, the signal of illegal touch in the training process is collected, processed and displayed in real time. Combined with the video image recognition technology, the tactical movements are compared to judge. Wireless transmission method is adopted to send the assessment results to the background management center for analysis and statistics, which is used to improve the timeliness, accuracy and fairness of the individual soldier assessment training.

In order to solve the problem of low connection strength between elastic skin and honeycomb sandwich of composite flexible skin for variant aircraft, a “two-step bonding” connection scheme is proposed. Firstly, the polyurethane fiber cloth and honeycomb are bonded by epoxy resin structural adhesive, then the silicone rubber sheet and the spandex fiber cloth are bonded by the silicone rubber adhesive, and the manufacturing method is given. Finally, “two-step bonding” experimental piece and “direct bonding” experimental piece were prepared respectively, and the bonding strength experiment and comparative analysis were carried out, The results show that the bonding strength of the “two-step bonding” experimental piece is five times that of the “direct bonding” experimental piece.

ObjectiveTo explore the influence of the core symptoms of attention deficit hyperactivity disorder （ADHD） on behavioral problems of children with ADHD propensity， so as to provide references for early identification and targeted intervention for children with ADHD propensity.MethodsFrom July to August 2021， 25 children with ADHD propensity were screened as the ADHD propensity group， and 25 children matched for age， gender and grade were included as the normal group in an elementary school in Guangzhou. ADHD core symptoms were assessed by the Chinese version of the Swanson Nolan and Pelham， version IV-parent form for ADHD （SNAP-IV）， and behavioral problems were assessed by Questionnaire-Children with Difficulties （QCD） and Conners Parental Symptom Questionnaire （PSQ）. Spearman correlation analysis was used to examine the correlation between ADHD core symptoms and QCD and PSQ scores， and hierarchical linear regression analysis was used to explore the effect of ADHD core symptoms on behavioral problems.Results① The differences between the groups showed that both attention deficit and hyperactivity-impulsivity factor scores were higher in the ADHD propensity group than those in the normal group （t=7.771， 6.726， P

Objective To study the demographic and clinical characteristics, correlation of genotype and phenotype and treatment of Blau syndrome to facilitate early diagnosis and timely treatment of Blau syndrome. Methods Seventy-two patients with Blau syndrome from 11 centers from May 2006 to April 2022 were retrospectively analyzed, and their general information, clinical data, laboratory examination and treatment medication were collected. Results The distribution of patients with Blau syndrome was uniform in geographical north and south of China, and there was no obvious gender bias. The mean age of onset was (14.30±12.81) months, and the age of diagnosis was (55.18±36.22) months. 35% of patients with Blau syndrome happened before 1 year old, and all patients developed before 5 years old. 87.50% (63/72) had granulomatous arthritis, 65.28% (47/72) had rash, 36.11% (26/72) had ocular involvement, 27.78% (20/72) had fever, and 15.28% (11/72) had pulmonary involvement. Arthritic manifestations of Blau syndrome were most at risk, followed by rash, ocular involvement, and fever.The first 25 months of the disease, the risk of developing a rash was the greatest. The risk of developing arthritis was the greatest between 25 months and 84 months. The main mutations were p.R334Q and p.R334W, and patients with p.R334Q mutation had relatively high incidence of fever (35.71%[5/14] vs. 14.29%[1/7], P=0.43) and ocular involvement (42.86%[6/14]vs. 28.57%[2/7], P=0.51). There was a relatively high incidence of rash (85.71%[6/7] vs. 64.29%[9/14], P=0.59) in patients with the p.R334W mutation. Forty-five patients(62.50%)were treated with a combina-tion of glucocorticoid and methotrexate. Twenty-two patients were treated with tumor necrosis factor antagonist in addition to glucocorticoid and methotrexate. Conclusions The risk of different clinical manifestations of Blau syndrome from high to low was arthritis, followed by rash, ocular involvement and fever. The main treatment was glucocorticoid combined with methotrexate, to which biological agents could be added.

The traditional speech enhancement algorithm based on generative adversarial networks (SEGAN) enhances speech in the time domain,and completely ignores the distribution of speech samples in frequency domain.Under the condition of low signal-to-noise ratio,the speech signal will be submerged in noise,and the time-domain distribution information of noisy speech is difficult to capture.Therefore,the enhancement performance of SEGAN will drop sharply,and the speech quality and speech intelligibility of its enhanced speech are very low.To solve this problem,this paper proposes a speech enhancement algorithm (time-frequency domain SEGAN,TFSEGAN) based on time-frequency domain generation confrontation network.TFSEGAN adopts the model structure of the time-frequency domain dual discriminator,and a time-frequency L1 loss function.The input of time domain discriminator is time domain feature of the speech sample,and the input of frequency domain discriminator is frequency domain feature of the speech sample.In the training process,time-domain discriminator uses the time-domain distribution information of speech sample as the criterion,and frequency-domain discriminator uses the frequency-domain distribution information of the speech sample as the criterion.Under the action of two discriminators,the generator of TFSEGAN could simulta-neously learn the distribution rules and information of speech samples in time domain and frequency domain.Experiments prove that,compared with SEGAN,the speech quality and intelligibility of TFSEGAN improve by about 17.45% and 11.75% respectively at low signal-to-noise ratio.

Plaque pH detection technology can detect the risk of caries and assist in the prevention of caries, with a mature theory and a relatively simple operation. With the increasing demand for clinical caries risk detection technology and the rapid development of microelectrode techniques, there is an increasing variety of types of microelectrodes that can detect the pH of dental plaque, including glass microelectrodes, metal oxide microelectrodes and ion-sensitive field effect transistors. The glass microelectrode was the first microelectrode to be applied in this field, but its structure is weak. Among the various options, the iridium oxide microelectrode has become the most promising caries risk detection electrode in recent years because of its high strength and excellent response. Metal oxide microelectrodes can also effectively compensate for the insufficient strength of glass microelectrodes. With advances in electrode technology, miniaturized, sensitive ion-sensitive field effect transistors have attracted the attention of researchers. Scientists have also recently developed a way to detect the pH of dental plaque with an optical no-contact technique. Optical contactless detection technology will not damage the dental plaque structure, so it has great research and clinical prospects. Future research will further improve the strength and performance of these electrodes on the premise of ensuring miniaturization and achieving noncontact detection.

Objective To investigate the effects of high-salt diet on the maturation and function of NK cells. Methods Mouse models of normal salt diet (NSD) and high salt diet (HSD) were established by feeding food and drinking water with different salt content. The expression of CD27 and CD11b was used to define the NK cell maturation subsets, and the early activation of cells was labeled by CD69. Flow cytometry was employed to analyze the distribution of NK cell subsets and activation in NSD and HSD mice. The IFN-γ production level of NK cells from mice treated with polyI: C for 18 h in vivo and stimulated with PMA/Ionomycin for 4 h in vitro was detected by flow cytometry. Cytotoxic activity of NK cells was determined through the YAC-1 killing experiment in vivo. Results HSD showed no effect on the percentage of NK cells in the liver, spleen, bone marrow and peripheral blood, but inhibited the expression of CD69 in liver and spleen NK cells (P < 0.01). The percentage of immature NK cells (CD27+CD11b-) subsets was significantly higher in the liver, spleen and bone marrow from HSD mice when compared to those in NSD mice (P < 0.05), while the percentage of mature M1 NK cell subsets (CD27+CD11b+) as well as DX5+NK1.1+ mature NK cells were markedly lower in HSD mice (P < 0.05), suggesting that HSD inhibits the maturation of NK cells. The expression of IFN-γ in NK cells of HSD mice was lower than that of NSD mice (P < 0.01), indicating that HSD inhibited NK cell function. Moreover, YAC-1 in vivo killing experiment showed that the percentage and absolute number of residual YAC-1 cells in the abdominal cavity of HSD mice were higher than those of NSD mice (P < 0.01), indicating that HSD inhibited the cytotoxicity of NK cells. Conclusion HSD inhibits the maturation of NK cells as well as the activation and function of NK cells.

Parkinson's disease (PD) is a common neurodegenerative disease and the disease burden is increasing. Neurofilament light chain (NfL) is a neuronal cytoplasmic protein highly expressed in large calibre myelinated axons which may serve as a biomarker for axonal damage. NfL is one of the most promising biomarkers to be used in clinical diagnosis and differential diagnosis of PD and it also plays an important role in predicting the severity and progression of PD and associated cognitive disorders. Besides, NfL combined imaging biomarkers also has high predictive value. This review provides an overview of the progress achieved thus far exploring the assicaiton between NfL in cerebrospinal fluid or blood, with a view to be providing help for clinical practice and follow⁃up studies.

To explore the protective effect and possible mechanism of probiotics combined with resveratrol on chronic alcoholic liver injury, C57BL/6J mice were used to construct chronic alcoholic liver injury model. Mice were randomly divided into the control group (Con group), themodel group (Mod group), three intervention groups of probiotics combined with resveratrol (Res) (Lactobacillus paracasei J5+Res (J5+Res), Lactobacillus casei YRL577+Res (YRL577+Res), Bifidobacterium animalis F1-7+Res (F1-7+Res)) groups, and the positive drug tiopronin group (LP group). After the experiment, the liver lipid content, alcohol metabolism enzyme activities, oxidative stress level and other indexes of mice were investigated. In order to further explore the mechanism of the combined action, the mRNA expressions of oxidative stress related genes CYP2E1, nuclear factor erythroid-2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) in liver were analyzed. The results showed that compared with Mod group, probiotics combined with resveratrol could significantly reduce the contents of triglyceride, total cholesterol, serum aspartate aminotransferase and alanine aminotransferase activites in liver of mice (P

Based on the background of large amount of solid waste alkali slag, high treatment cost and environmental pollution, the feasibility of using alkali slag to improve mechanical properties of gangue cemented backfill material was discussed. In this paper, the basic physical and mechanical properties of alkali slag are tested, and the influence law and strength mechanism of alkali slag content and curing age on mechanical properties of cemented filling materials are studied. The results show that: with the increase of alkali slag content in the range of 0%-12%, the strength of the backfill in the early stage, the middle stage and the later stage show the law of first strengthening and then decreasing; the optimum mix ratio of alkali slag cemented backfill material is alkali slag∶ fly ash∶ lime∶ cement∶ gangue∶ used aggregate=6%∶34%∶10%∶2.5%∶24%∶23.5%, and the early strength and late strength of the material increase up to 449% and 187%; C-S-H cementation coexists with N-A-S-H cementation in the slurry system of alkali slag cemented backfill material, and N-A-S-H cementation has stronger cementation performance, which reduces the connectivity of pores. An appropriate amount of alkali slag can effectively improve the strength of the material. The cemented filling material prepared by alkali slag can realize energy saving and emission reduction, and its technical, economic and social benefits are remarkable, and it has good engineering application value.

ObjectiveTo evaluate the safety of β-glucan biofortified rice through a 28-day oral toxicity test.MethodsWeaned SD rats were randomly divided into a control group and low, medium and high dose groups (2.5, 5.0 and 10.0 g/kg BW), 22 in each group, half male and half female. After oral gavage (10 mL/kg BW) and continuous administration for 28 d, eyes were examined before and after the experiment. After the animals were sacrificed, urine routine, hematology, blood biochemistry, organ coefficient measurement and histopathology examination were performed.ResultsCompared with the control group, there were no significant differences in the appearance, weight, food utilization, organ coefficient, blood biochemistry, and urine routine tests in the sample group. Compared with the control group, the food intake of the male medium, high-dose group and the female high-dose group was statistically different (P

【Objective】 Water consumption by crops depends on many abiotic and biotic factors. The purpose of this paper is to investigate how planting pattern and seeding rate affect water uptake by crops and its consequence for water use efficiency. 【Method】 The experiment was conducted in a field with spring wheat used as the model plant. It consisted two planting patterns: Traditional strip planting, and widen strip planting. For each planting pattern, there are five seeding rates: 390 kg/hm2 (D1), 420 kg/hm2 (D2), 450 kg/hm2 (D3), 480 kg/hm2 (D4) and 510 kg/hm2 (D5). During the experiment, we measured and calculated water consumption, grain yield and water use efficiency of the wheat. 【Result】 Seeding rate affected water consumption the most in all growing stages. In the jointing-milk ripe stage and milk ripe-complete ripeness stage, the planting pattern and seeding rate combined to affect water consumption at significant level. When drilling the seeds in the widen strip, water consumption of the wheat increased with seeding rate peaking in D4 treatment, while when sowing the seeds in traditional strip, water consumption of the wheat maximized in D3 treatment. Widening the sowing strip increased the wheat yield of D2, D4 and D5 by 5.3%, 21.0% and 28.3%, respectively, compared their associated seeding rate in traditional planting pattern. The highest grain yield was D4 drilled in the widen planting pattern, increasing by 8.8% compared with D3 planted in traditional strip. On average, increasing seed rate by each 30 kg/hm2 in the widen strip planting pattern led to a 8.4% increase in grain yield, equivalent to 133.2% of the yield of traditional planting strip. The maximal water use efficiency (WUE) was in D4 sowed in the widen strip, which was 6.6% higher than the maximal WUE achieved in D3 planted in traditional strip. 【Conclusion】 Seeding rate was the factor affecting water consumption of spring wheat the most; widening sowing strip combined with increasing seeding rate can improve grain yield and WUE of the wheat. In our experiment, widening the sowing strip combined with 480 kg/hm2 of seeding rate were most effective in simultaneously improving wheat yield and water use efficiency.

BACKGROUND From 1986 to 2007, different grades of trace gold certified reference materials (background grade, anomaly grade, medium grade and high grade) and mineral gold certified reference materials (mineralization grade, cutoff grade and concentrate grade) had been developed by IGGE and used for regional geochemical survey, mineral exploration and evaluation, mining and smelting. With the increase of the service life period and the consumption of recent years, most of the gold certified reference materials has been used up or almost used up. New gold standard materials need to be developed urgently. OBJECTIVES To develop a new gold certified reference material and compare it with the original gold certified reference material. METHODS The trace gold certified reference materials in 7 levels and mineral gold certified reference materials in 3 levels were prepared in strict accordance with relevant specifications. The collected candidates were sampled from different types of deposits and different matrices. The collected candidates were prepared through coarse crushing, drying, composite configuration, fine crushing, sieving, blending and other steps. After the particle size inspection, the cumulative content of the sample with a particle size of 0.74μm reached more than 99%, which met the requirements of the specifications. 25 bottle samples of each grade were randomly selected. Homogeneity testing was carried out by ICP-MS, FAAS and GFAAS. RESULTS The relative standard deviation (RSD) was less than 10%, and the F values of the variance test were less than the one-tailed critical value F0.05(24, 25) of 1.98, indicating that the sample uniformity was good. During the one-year investigation period, no significant changes in statistical significance were found in the fixed value components, which proved that the stability of the sample was good. Five highly experienced and skilled laboratories in geology gold samples testing in CHN were invited to evaluate the gold certified reference materials by classically reliable analytical methods. The original data conformed to the normal distribution after statistical inspection and the suspicious values were eliminated. The arithmetic mean was used as the standard value, and the uncertainty was evaluated in detail, in accordance with the latest specifications. The certified value of the copied standard material was accurate and reliable, and the uncertainty was reasonable. It was approved as a national first-level standard material in 2019. Compared with the original batch, the certified values of the two batches were basically the same, and the standard deviation of the fixed value data showed a shrinking trend, which met the requirements for copying standard materials. CONCLUSIONS This series of gold standard materials has a wide content range, and meets the value comparison and analysis monitoring of different content levels. Moreover, it has good applicability, and meets the needs of geological and mineral research, regional geochemical investigation, gold mine exploration and evaluation.

On June 9，2020，an earthquake measuring ML3.4 occurred in Shapotou District，Zhongwei City，Ningxia. The earthquake occurred in the meizoseismal area of the 1709 M7½ earthquake of South Zhongwei，and its epicenter is located in an area where there were relatively few weak earthquakes in the past. In this paper，based on the waveform records of the Ningxia regional seismic network，the focal mechanism solution and focal centroid depth of the Zhongwei ML3.4 earthquake on June 9，2020 are inversed using the gCAP method. The focal mechanism solution is also calculated by the Hash method，and the central focal mechanism of these two methods is obtained. The result shows that the focal mechanism solution of gCAP method is strike 255°，dip 79°，rake −20° for nodal plane I，and strike 348°，dip 70°，rake −160° for nodal plane II，and the centroid depth is 12 km，and that the focal mechanism solution of Hash method is strike 344°，dip 89°，rake 176° for nodal plane I，and strike 74°，dip 86°，rake 1° for nodal plane II. The central focal mechanism solution of the two methods is strike 255°，dip 87°，rake −11° for nodal plane I，and strike 346°，dip 80°，rake −176° for nodal plane II，and the principal stress axis is mainly in NE direction. The minimum 3-D rotation angle between the gCAP method result and the central focal mechanism is relative small，which is 12.09°. Combing the past geologic structure data，we deduces that the main dislocation of Zhongwei ML3.4 earthquake on June 9，2020 is the left-lateral slip，and that the fault is more likely to belong to the nodal plane in NEE direction.

The standards system for supporting high-quality development is based on the development concept of “innovation, coordination, green, openness, and sharing” and supports the all-round, high-quality development of China’s economy, society, and ecology. Conducting strategic research on this standards system plays a basic and leading role in promoting economic development, ecological environment quality, and social governance level, and is significant for meeting people’s needs for a better life. In this article, we analyze the concept of high-quality development as well as the connotation and characteristics of the standards system for supporting high-quality development, and study the difference between the high-quality development standards system and existing systems. Moreover, this study presents the main directions and implementation paths for the standards system by 2025 and 2035, focusing on agriculture, manufacturing, services, social governance, ecological civilization, and other key areas. Furthermore, we propose corresponding countermeasures in aspects of top level design, standardization policies, standardization capability improvement, and standardization personnel training, hoping to provide references for the development of the aforementioned key areas and for the decision making of relevant government departments.

BackgroundNeutron radiography (NR) is an important nondestructive testing method. NR is particularly useful for detection of light materials in medium and large heavy samples. Especially, the fast neutrons can penetrate the heavy materials and reveal the structure of the light materials. Compared to accelerator neutron sources, the fission neutrons elicited from a reactor are stable and of high quality. The fission neutron imaging is a useful complementary testing technology, especially for industrial applications that require high throughput and large-scale testing.PurposeThis study aims to investigate the super field of view neutron imaging by fission neutrons elicited from research reactor.MethodsBased on theoretical analysis and Monte-Carlo simulation, one filter combination was employed to improve the proportion of fission neutrons in the thermal neutron beamline at China Mianyang Research Reactor (CMRR). A fission neutron imaging system was constructed by employing a large field fast neutron fluorescent screen, short focus distance lens, and scientific charge coupled device (CCD) camera. Finally, some samples were tested using fission neutron tomography.ResultsThe fission neutron flux reaches up to 3×105 cm-2·s-1 when the L/D ratio is about 260. The field of view of NR is up to 400 mm×400 mm with resolution was better than 0.5 mm. Using super field of view method, samples less than 600 mm can be tested with this new system.ConclusionsCombination of theoretical calculation and experimental methods, fission neutron imaging can be improved to overcome some of the limitations of traditional neutron radiography techniques, and meet the needs of large sample detection in the future.

In order to study the behavioral causes of coal mine rock burst accidents, 24Model was applied to analyze the unsafe acts and physical causes of 10 typical rock burst accidents occurred after 2011. The results show that the depth of 80% of the rock burst accidents is over 800 m, 50% of the accident points are located in the fault area, and 90% of the rock burst accidents occur in the state-owned key coal mines. The occurrence process of the rock burst accidents can be divided into two stages: the formation process of the high stress concentration zone and the process of eliminating the rock burst risk. Seven categories of unsafe actions, which mainly include risk operation and failure of anti-impact measures, are obtained to eliminate the failure of rock burst hazard.

Since an epidemic occur of Corona Virus Disease 2019(COVID-19) in December, 2019, all the dental healthcare service providers in our country have been greatly impacted. The strategy of managing the dental clinics is quite different from that of the medical healthcare clinics, and the key point of the administration of those dental healthcare providers is to focus on the management of outpatient care because they only supply just a little bit of inpatient care service but quite an large amount of outpatient care service. So we think the next step is to make plausible and effective scenarios to protect our dental healthcare staff and patients against corona virus infection during the treatments procedures after the reopening all of our dental clinics. To overcome this harsh condition, the infection prevention and control strategies adopted by the Stomatological Hospital, Southern Medical University were designed to be flexible and could be adjusted promptly according to the national and local governmental orders and latest guidelines released by the Centers for Disease Control and Prevention. All these prevention procedures and protocols were customized to fit our own situation and have been updated for several times based on the latest global pandemic reports. After going through the hardest time in the past four months, it’s considered that our COVID-19 prevention rules have been proved to be efficient and work well. Further more, it has made massive progress for the hospital in improving the capability of dealing with this state of emergency, especially by previewing and triaging patients strictly to cut off the possible coronavirus spreading from the original step, enhancing the standard precautions and those specific protocols made for minimizing the droplets, aerosol and contact transmission of COVID-19 indoors. Besides, a daily supervision system was set up as a routine job and a team of qualified infection prevention specialists were assigned to check and report every incorrect details during the whole procedure of dental practice. Meanwhile, the safety and well-being of the public and our medical workers could be also guaranteed through following those detailed prevention scenarios.

In recent years,structural magnetic resonance imaging (sMRI) and functional magnetic resonance imaging (fMRI) are widely used in depression research.From the perspectives of morphology,structural network and functional network,the brain abnormalities of depression were explored to understand the pathogenesis,and to assist doctors in clinical diagnosis,treatment and prognosis.A large number of researches have found that the hippocampus and amygdala of depression showed different degrees of atrophy,and the connection strength of brain network and graph theory attributes showed significant abnormal.Moreover,the abnormal brain areas were related to emotional regulation,attention and cognitive control,and the degree of abnormalities were highly correlated with the severity of depression.The research actuality of depression from different perspectives was reviewed,and some suggestions for future research were put forward.

Objective To investigate the contamination situation of Salmonella at different times, slaughtering and processing sites in a broiler slaughter factory to acquire the key contamination point. Methods Chicken anal swabs, carcasses and broiler samples in different slaughtering stages were timely collected in a broiler slaughterhouse in Shaanxi Province from November 2016 to November 2017, Salmonella concentration was quantitatively detected by most probable number (MPN) method, Salmonella isolate recovered from positive samples were identified by polymerase chain reaction (PCR) combined with serum agglutination techniques. Results Among the 284 samples, 67 (23.6%) were positive to Salmonella, the average MPN value was 0.051 6 MPN/g. During sampling period, samples in July was the most frequently contaminated with the positive rate of 37.8% (14/37) and average MPN value of 0.064 7 MPN/g. the lowest Salmonella contamination rate was detected in November 2016 (13.9%, 5/36) with average MPN value of 0.043 6 MPN/g. Among different processing stages, the highest positive rate was detected after scalding and fading (43.3%, 26/60), the average MPN value of which was 0.060 5 MPN/g. The positive rate of chicken breast before freezing was the lowest (18.3%, 11/60), and the average MPN value was 0.036 8 MPN/g, which was slightly higher than that of the whole chicken carcass/chicken breast collected from distribution and storage processes (0.035 8 MPN/g). Conclusion The result showed detection rate and MPN values of Salmonella positive samples in broiler slaughtering process had a strong seasonality, detection of Salmonella in different slaughtering stages indicated that vertical and cross-contamination might happen during the whole process. It was necessary to strengthen the regulation of broilers processing as well as the critical control points.

BackgroundNuclear critical safety analysis is the key technology to ensure the safety of spent fuel reprocessing plant. However, the present critical safety analysis codes for solution system are either limited in the geometric scope of application, or have poor engineering practicability due to low computational efficiency.PurposeThis study aims to develop a method suitable for wide application range and high accuracy for nuclear critical safety analysis, so as to provide technical support for spent fuel reprocessing plant.MethodsAccording to the characteristics of spent fuel solution system, a set of methods, such as the zero-dimension cross-section calculation and whole system group condensation model, the three-dimensional space-time neutron dynamics model based on PCQS, and the R-Z two dimensional thermal and radiolysis gas simulation model, were combined to establish a paralleled 3D critical safety analysis code hydra-TD. In addition, some experiments of SILENE facility at France were modeled and calculated by using hydra-TD code to verify its effectiveness.ResultsThe verification results indicate that there are very small errors of key parameters such as the first fission power peak, multiplication time and total fission times.ConclusionThe code hydra-TD developed in this study can be applied to simulation of the multi-physics processes in the critical transients of the fuel solution, hence has the ability of critical safety analysis.

In the 5G era,growth of network traffic is driven by the development of emerging services,especially the burst of east-west traffic.The network evolved from a multi-layered planar architecture to a three-dimensional architecture,thereby promoting the development and application of all-optical switching technology.The development and technology evolutions of optical switching architecture were introduced,the key enabling technologies and applications of all-optical switching equipment were described,and the future trends of all-optical switching technology were discussed.

Because of the low recovery of -10 μm fine scheelite particles in scheelite flotation, some amount of fine scheelite is lost in the tailing, resulting in the wasting of scheelite resources. It is urgently needed to solve the problems inherent in fine scheelite flotation and explore new processes of fine ores to effectively recover fine scheelite. The carrier flotation has proven to be an effective method of improving the recovery of scheelite by promoting the recovery of fine particles. Based on studies of the effect of particle size and particle fraction on scheelite flotation, the application of auto-carrier flotation in the recovery of -10 μm scheelite using sodium carbonate in both the presence and absence of sodium carbonate were studied. The effect of percentage carrier, particle size of carrier, and sodium carbonate on the auto-carrier flotation of scheelite were also studied through flotation tests, theoretical calculation, and instrument testing. The results indicate that the contents and particle size of coarse particles exert significant influence on auto-carrier flotation. The recovery of fine scheelite with a size of -10 μm is increased by using auto-carrier flotation with the proper carrier percentage and size. The addition of sodium carbonate strengthens the carrier flotation of scheelite and therefore improves the scheelite recovery. Furthermore, the addition of sodium carbonate can also expand the percentage and particle size range of carrier mineral. The results of mechanism studies indicate that there exists interaction among scheelite particles, which results in the adhesion of fine particle to carrier. The hydrophobic force is the main reason that the scheelite particles attracted each other, and the addition of sodium carbonate increases the adsorption of sodium oleate onto the scheelite surface, thereby improving the hydrophobicity of scheelite and the hydrophobic force among scheelite particles. It can be concluded that the auto-carrier flotation of scheelite can be improved by adding sodium carbonate.

BackgroundAccurate mass measurement of radionuclides can be achieved by calorimetry which is considered to be one of the most convenient and accurate non-destructive analytical methods for nuclear materials.PurposeThis study aims to develop a radionuclide calorimeter for efficient measurement of radionuclides bearing samples of specially designed container size and power range.MethodsFirst of all, a dual-compensated heat-flow calorimeter was designed and developed by precise component instruments selection, structural optimization and reasonable selection and manufacture of key temperature difference sensors. Then, automatic measurement and control method was combined to solve the key technical difficulties of calorimetry. Finally, an electrothermal source sample was adopted to test performance of the developed calorimeter.ResultsExperimental test results show that the measurement precision is within 0.2% in steady-state equilibrium mode. The deviation between measured result and input power is within 5% when the input power is set to 30 mW.ConclusionsThe developed radionuclide calorimeter can be used to measure thermal power at watts magnitude.

The grain orientation and the interface character distribution were investigated for γ precipitation from the supersaturated α during aging at 1323K in duplex stainless steel by using EBSD technique and misorientation analysis based on Rodrigues-Frank (R-F) space. The results show that sharp texture and the grain boundary character distribution featured by a high population of low angle grain boundary (LAB) and a small number of twin boundaries (TBs) are produced in the γ precipitated from cold-rolled supersaturated coarse α with pre-strain of ε=2. The precipitated γ grains approximately possess K-S, N-W and Bain orientation relationship with the α matrix equally. For the unstrained α matrix of the same orientation, nearly random texture and the grain boundary character predominated by TBs are introduced in the γ precipitation after aging. Most of γ have K-S relation with the α matrix. However, twining in γ leads to the deviation from typical K-S orientation relationship. And also, one-fourth of phase boundaries along γ grains containing twins are found to obey a new orientation relationship of 35°/〈110〉 with α matrix.

[Purpose/significance] The paper analyzes the 542 literatures related to knowledge organizations in 2007-2016, which are included in the core database of Web of ScienceTM, and aims to grasp the current research situation in this field and provides references for domestic relevant research. [Method/process] Based on the method of bibliometrics, the CiteSpace software was used to analyze and draw the knowledge map from the aspects of annual issuers, authors, countries and research institutions, keywords, co-citation and so on. [Result/conclusion] The results show that authors the most publications are B. Hjorland, I. Dahlberg , V. Broughton etc; the cooperation between researchers and institutions is relatively rare; knowledge organization research areas focus on the knowledge organization itself and classification, ontology and so on; B. Hjorland, H.A. Olson, I. Nonaka and other cited scholars and their cited literatures have high influence on this theme; Knowledge Organization, Journal of Documentation is most important journals for the knowledge organization.

Copyright of Chinese Journal of Lung Cancer is the property of Chinese Journal of Lung Cancer and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

From June 2003 to May 2004, the precipitation at Changshu Agro-ecological Station (31° 32′45" N, 120° 41′57" E) of Chinese Academy of Sciences was collected to monitor its particle- and dissolved nitrogen and phosphorus concentrations, with the seasonal variation of nitrogen and phosphorus in wet deposition in Taihu Lake region investigated. The nitrogen input from wet deposition had an obvious seasonal variation, being higher in summer and spring and lower in autumn and winter. The ratios of dissolved nitrogen (DN) and particle nitrogen (PN) to total nitrogen (TN) in wet deposition were 88.2% and 11.8%, and those of dissolved phosphorus (DP) and particle phosphorus (PP) to total phosphorus (TP) were 53.3% and 46.7%, respectively. The amounts of nitrogen and phosphorus deposited into Taihu Lake region by light and medium precipitation were higher than those by heavy precipitation. The annual input of TN and TP from wet deposition was 30.2 kg · hm2 and 1.1 kg · hm2, respectively, and the DN concentration in all precipitation events as well as the DP concentration in 92.5% of precipitation events was higher than the thresholds of inland water eutrophication. [ABSTRACT FROM AUTHOR]

Aiming at the research of pure electric power transmission,the single low-power motor has the problems of low power,small speed range which can cause motor damage and the single high-power motor has the problem of large own load,large energy loss and other issues. A differential type parallel coupled input single output power transmission test bench is designed,the relationship between input and output speed and power loss when the load changed under different working modes is studied. The results of simulation test and the test bench test run shows,when the motor reaches steady state operation,the rated power is 0. 49 k W,the average output power is about 0. 482 k W,power loss is less than 10 W,speed range increases 29. 17%,transmission efficiency is greater than 81. 7%,output power is enhanced effectively and also has fine repeatability. The experimental research platform is provided for the further research on the dynamic optimization of the coupling transmission system.

Objective To investigate the clinical and EEG features of ischemic stroke patients with abnormal discharges. Methods Clinical data and 24-hour EEG monitoring of 162 ischemic stroke patients were analyzed retrospectively. One-year follow-up was carried out and post-ischemic epilepsy was diagnosed. Results Among 162 ischemic stroke patients, 24-hour EEG was abnormal in 87 cases (53.70%). According to the correspondence of site of infarcts and abnormal discharges, these 87 cases were classified into 2 groups: matched group (N = 24, 27.59%) and unmatched group (N = 63, 72.41%). There was no significant difference between 2 groups in terms of Oxfordshire Community Stroke Project (OCSP) and TOAST classification (P = 0.792, 0.111), while there was significant difference between 2 groups on the site of infarcts (P = 0.000). In matched group, the infarcts were mainly located in cortex (N = 23, 95.83%). However, in unmatched group, the infarcts were mainly located in cortex and basal ganglia (N = 27, 42.86%), or in basal ganglia only (N = 24, 38.10%). In matched group, 24-hour EEG showed slowing of background activities, and sharp waves and sharp and slow wave complex which were corresponding to the infarct sites. The abnormal discharges could only be recorded around the infarct unilaterally. In unmatched group, the epileptiform discharges were recorded in both contralateral and ipsilateral ischemic hemispheres, usually with widespread slow waves and asymmetric background. The infarcts were limited, but abnormal discharges were widespread. For example, the infarct was located in deep brain, while scalp abnormal discharges were recorded. Although there was no significant difference in terms of epilepsy incidence between 2 groups (P = 0.908), the types of epilepsy were statistically different between 2 groups (P = 0.000). In matched group, the main type was partial seizure. But in unmatched group, the main types of epilepsy were secondary generalized seizure and generalized seizure. Conclusions Infract site has an influence on the abnormal EEG pattern, and the unmatched location of ischemic region and abnormal EEG may be indicative for the seizure type of post-ischemic epilepsy. DOI: 10.3969/j.issn.1672-6731.2016.05.008

Objective To explore the clinicopathological features of adult medulloblastoma with myogenic differentiation and to discuss clinicopathological differentiations from relevant tumors, so as to improve the ability of diagnosing and differentiating this kind of tumor. Methods The clinical manifestations, imaging, pathological features and immunohistochemical features of one case of adult medulloblastoma with myogenic differentiation were analyzed, and related literatures were reviewed. Results A 32-year-old female patient presented with repeated distortion of mouth and facial numbness for over 6 years. T1WI showed a mixed-signal lesion in the cerebellar vermis and dorsal part of brainstem, and protruded toward the fourth ventricle. Enhanced T1WI showed a round strengthened nodule in the lesion. During operation, it was seen that the tumor arised in cerebellar vermis, projected into the fourth ventricle and invaded brainstem. On microscopy examination, it was found that oval nuclei tumor cells were distributed in sheet or scattered patterns, and neuroblastic rosettes were observed. Abundant and eosinophilic cytoplasm, eccentrically placed and atypical nuclei containing hyperchromatic chromatin or prominent nucleoli in the tumor could be displayed. Mitoses were frequently seen. The tumor also presented with fresh and old hemorrhage in some place. Immunohistochemical staining showed that tumor cells were diffusely positive for integrase interactor 1 (INI1), synaptophysin (Syn), chromogranin A (CgA), human internexin neuronal intermediate filament protein α (INα), neurofilament protein (NF), Nestin (Nes), β-catenin and P53, and partly positive for desmin (Des), neuronal nuclei (NeuN) and S-100 protein (S-100), but negative for glial fibrillary acidic protein (GFAP), oligodendrocyte transcription factor-2 (Olig-2), CD99, pan cytokeratin (PCK), epithelial membrane antigen (EMA), MyoD1, myogenin, muscle-specific actin (MSA) and smooth muscle actin (SMA). Ki-67 labeling index was about 10% . Pathological diagnosis was medulloblastoma with myogenic differentiation (WHO Ⅳ). The patient was not given further treatment including chemotherapy or radiotherapy after surgery. Nine-month follow-up showed no tumor recurrence. Conclusions Medulloblastoma is a malignant, invasive embryonal tumor commonly occuring in the cerebellum of children. Medulloblastoma with myogenic differentiation occurs very rarely in adult, which is characterized by containing primitive neuroectodermal and rhabdomyoblastic elements. The diagnosis should be differentiated from central nervous system primitive neuroectodermal tumor (PNET), atypical teratoid/rhabdoid tumor (AT/RT) and rhabdomyosarcoma. DOI: 10.3969/j.issn.1672-6731.2015.09.009

For inconvenient emergency stop control with low reliability of existing electro-hydraulic control equipment of hydraulic support, an emergency stop control scheme for electro-hydraulic control system of hydraulic support was proposed which was based on C8051F020 single chip microcomputer. A transmission mode taking special RS485 bus as emergency stop signal channel was drawn up as well as concrete implementation scheme of interlocking of emergency stop and reset. Meanwhile, functions of fault location, fault diagnosis and power-off memory for emergency stop state of support controller were achieved by use of software. An electro-hydraulic control system of hydraulic support based on the emergency stop control scheme has run in a coal mine with good effect.

In view of problem of low automation degree of current electro-hydraulic control system for hydraulic supports, a centralized control system for hydraulic supports on fully-mechanized coal mining face was designed, designs of hardware and software of the system were introduced, and realizing process of centralized control for hydraulic supports was also expounded. The test results show that the system can realize centralized control of hydraulic supports, and has performances of stable field communication and high real-time, which can meet actual requirement of coal mine production.

Objective To investigate the occupational exposure and its risk fatctors among the medical staff of stomatological department and, in order to improve the occupational protection and reduce the risk for occupational exposure.Methods The occupational exposures that occurred in 44 medical staff from Jan 2013 to Dec 2015 were investigated, and the occupation, exposure sources, types of exposures, exposure link were analyzed.Results Among the 44 medical staff of oral department with occupational exposure, doctors accounted for 54.5%, nurses 34.1%. There were 39 medical staff with sharps injuries and 3 medical staff with mucous membrane exposure. The major expose reason is cleaning medical instruments or equipment at the end of medical treatment, accounting for 43.2%(19 cases). Needle stick injures in operation is the second major reason, accounting for 34.1%(15 cases). All the subjects with occupational exposures have received appropriate treatment, and the follow-up showed that none of the medical staff were infected due to the occupational exposure.Conclusion The major expose reason is cleaning medical instruments or equipment at the end of medical treatment. It is crucial to intensify the training of medical staff of stomatological department in the knowledge of occupational exposure, implement the standard of preventive measures, and standarize the operation procedures so as to reduce the risk of occupational exposure.

The motion simulation model and finite element model of drill pipe handing manipulator are established respectively by using ADAMS and ANSYS,the movement simulation and strength analysis of the manipulator are carried out. The results show that the trajectory of manipulator is approximation level,and has no velocity fluctuations which can meet the stability requirement of manipulator in pipe moving work. When the claw is under linear horizontal load,the load of hydraulic pump increased with the displacement increase,more than a certain position,the load increased rapidly. When the manipulator sustained the maximum load in the limit position,the maximum stress occurred on the back arm and forearm,the hazard zone concentrated near the hinge hole. The obtained result can provides a reference for performance evaluation and structure optimization of drill pipe handing manipulator.

To solve problem of lacking remote monitoring function of running status in existing electro-hydraulic control system for hydraulic support, a running status monitoring system for hydraulic support based on dual RS485 buses was developed. In the system, an enhanced RS485 serial communication mode is used with data transmission speed of 10 Mbit/s. Dual RS485 buses communication mode is used for collateral execution of online monitoring and remote control. Some anti-interference measures are used in hardware circuit design including opto-coupler isolation circuit, high voltage intrusion prevention circuit and fault protection circuit, which has passed surge immunity test according to GB/T 17626.5-1998. The test results in laboratory and field show that the system realizes remote and online monitoring of running status of hydraulic support with strong real-time performance and anti-interference performance.