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Objective To investigate the age-related changes of the mandibular third molar root pulp visibility in individuals in East China, and to explore the feasibility of applying this method to determine whether an individual is 18 years or older. Methods A total of 1 280 oral panoramic images were collected from the 15-30 years old East China population, and the mandibular third molar root pulp visibility in all oral panoramic images was evaluated using OLZE 0-3 four-stage method, and the age distribution of the samples at each stage was analyzed using descriptive statistics. Results Stages 0, 1, 2 and 3 first appeared in 16.88, 19.18, 21.91 and 25.44 years for males and in 17.47, 20.91, 22.01 and 26.01 years for females. In all samples, individuals at stages 1 to 3 were over 18 years old. Conclusion It is feasible to determine whether an individual in East China is 18 years or older based on the mandibular third molar root pulp visibility on oral panoramic images.

Aiming at the problem of insufficient impact resistance of the existing portal support, a kind of anti-impact support structure for multi-direction energy absorption was constructed by adding V-shaped groove to the beam structure and flexible chain support structures on both sides. Parameters such as total energy absorption, plastic strain and vertical displacement were used as analysis indexes to study the supporting performance of the support in the face of vertical impact and lateral impact, and the deformation degree for each structure of the support and the overall most vulnerable position were obtained. Under the vertical impact condition, the equivalent plastic strain position of the new support appeared at the middle joint of the top beam, and then the joint of the top beam should be thickened. In the whole process of vertical impact, the vertical displacement of the three hydraulic columns was not average, which indicated that the support was not very ideal in the face of concentrated impact. Under vertical impact conditions, the V-shaped groove had a small deformation in the face of the impact with large velocity, and a large deformation in the face of the impact with small velocity, which showed that the V-shaped groove had a certain response speed in the face of impact. Under lateral impact conditions, the equivalent plastic strain of the support was mainly concentrated at the connection between the flexible chain and the support when the impact velocity is low, and the annular base should be installed at the connection between the flexible chain and the support. The bearing capacity and total energy absorption of flexible chain support structure under lateral impact were slightly weaker than that of support under vertical impact, but they can play a good role in horizontal support.

Background and objective More and more patients with small pulmonary nodules (SPN) can be found along with the developing of chest low-dose computed tomography (LDCT). With current examinations not all the SPN can be diagnosed to be benign or malignant and not all the malignant nodules can be diagnosed to be lymphatic metastasis. We need to study the correlation between plasma D-dimer count of patients before surgery with pathology features of non-small cell lung cancer (NSCLC). Methods The study comprised 567 highly suspected lung cancer patients. Preoperative plasma D-dimer were qualified, and the relationship between plasma D-dimer with pathology features including benign or malignant nodules, tumor size and involvement of lymph nodes was examined using Kruskal-Wallis test and Spearman correlation coefficients. Results The median plasma D-dimer values were statistically higher in NSCLC patients than in those who suffered from benign lung nodules (P112.5 ng/mL) and malignant lymph node involvement in stage T1 lung cancer. Conclusion The plasma D-dimer maybe useful for early diagnosis, staging and prognosis of the patients with NSCLC. The plasma D-dimer can be one of the indicator to identify what kind of patients need mediastinal lymph node cleaning.

Objective To study the expression level of plasma miR-106b-5p in primary immune thrombocytopenia (ITP) and its correlation with the levels of T helper 17 cell (Th17) and regulatory T cell (Treg) and the Th17/Treg ratio. Methods A total of 79 children with ITP (ITP group) and 40 healthy children (control group) were selected as subjects. According to the treatment response, the 79 children with ITP were divided into three groups: complete response (n=40), partial response (n=18), and non-response (n=21). Quantitative real-time PCR was used to measure the expression level of miR-106b-5p. Flow cytometry was used to measure the frequencies of Th17 and Treg, and the Th17/Treg ratio was calculated. The correlation of the expression level of plasma miR-106b-5p with the frequencies of Th17 and Treg and the Th17/Treg ratio was analyzed. Results Compared with the control group, the ITP group had significantly higher levels of miR-106b-5p, Th17, and Th17/Treg ratio (P<0.05) and a significantly lower level of Treg (P<0.05). After treatment the ITP group had significant reductions in the levels of miR-106b-5p, Th17, and Th17/Treg ratio (P<0.05) and a significant increase in the level of Treg (P<0.05). Compared with the partial response and non-response groups, the complete response group had significantly lower levels of miR-106b-5p, Th17, and Th17/Treg ratio (P<0.05) and a significantly higher level of Treg (P<0.05). The correlation analysis showed that in the children with ITP, the expression level of plasma miR-106b-5p was positively correlated with the Th17 level and the Th17/Treg ratio (r=0.730 and 0.816 respectively; P<0.001) and was negatively correlated with the Treg level (r=-0.774, P<0.001). Conclusions A higher expression level of miR-106b-5p and Th17/Treg imbalance may be observed in children with ITP. The measurement of miR-106b-5p, Th17, Treg, and Th17/Treg ratio during treatment may be useful to the evaluation of treatment outcome in children with ITP. [ABSTRACT FROM AUTHOR]

Rice is the most important food crop in China and is of great significance for China's food security. This paper reviews the main achievements in rice pest management since the beginning of the 21st Century, from determining the population dynamics of major rice pests in China and the main factors influencing population growth and the development of non-chemical control technologies and emergency control technologies for rice pests over the past 20 years. Future prospects for rice pest management, such as improving prediction and forecasting, accelerating the cultivation and application of resistant varieties, strengthening the development, integration and innovation of green pest management technologies, improving the ability and service level of professional service organizations and strengthening policy support, are also discussed. [ABSTRACT FROM AUTHOR]

In this study, the brown planthopper (BPH), Nilaparvata lugens (Hemiptera: Delphacidae), cultured on Bt rice lines (T1C-19 with cry1C gene and T2A-1 with cry2A gene) and their parental rice MH63, were treated with a series of concentrations of triazophos and deltamethrin when they developed up to the third instar for the evaluation of the effects of Bt rice on BPH resurgence induced by pesticides. The results indicated that BPH nymphal duration decreased with the increasing concentration of deltamethrin, while no significant differences of BPH nymphal duration were observed on the same rice variety treated with the different concentrations of triazophos. Furthermore, the survival rate of BPH significantly declined and their fecundity significantly increased with the increasing concentration of insecticides. However, ecological fitness parameters of BPH including nymphal duration, survival rate, female adult mass, fecundity and egg hatchability were not significantly different among Bt and non Bt rice varieties when they treated with the same concentration of insecticide. These results implied that no significant difference in the BPH resurgence induced by pesticides was observed among the two tested Bt rice varieties and their non-Bt parental rice variety. [ABSTRACT FROM AUTHOR]

Plant viruses transmitted by arthropods, as an important biotic factor, may not only directly affect the yield and quality of host plants, and development, physiological characteristics and ecological performances of their vector arthropods, but also directly or indirectly affect the non-vector herbivorous arthropods and their natural enemies in the same ecosystem, thereby causing influences to the whole agro-ecosystem. This paper reviewed the progress on the effects of plant viruses on herbivorous arthropods, including vector and non-vector, and their natural enemies, and on their ecological mechanisms to provide a reference for optimizing the management of vector and non-vector arthropod populations and sustainable control of plant viruses in agro-ecosystem. [ABSTRACT FROM AUTHOR]

As a mental characteristic, vertical representation bias is introduced to portfolio choice model, to research its influence to investors' portfolio decision. This paper proposes Representation Return concept, and gives an investors' utility function of two variables -- final return and Excess Representation Return, from the principle of expected utility maximization. Then establishes optimal portfolio model based on vertical representation bias, and give an empirical analysis showing that the model can obtain efficient frontier of investment portfolio. [ABSTRACT FROM AUTHOR]

A laboratory study was made on the interactive effects of temperature (20 °C, 23 °C, 26 °C, 29 °C, and 32 °C) and nitrogen fertilization level (0 and 250 kg · hm-2) on the survival, development, and reproduction of brown planthopper (BPH) Nilaparvata lugens. With increasing temperature from 20 °C to 29 °C, the egg hatchability, nymphal survival, and adult fecundity of BPH increased and the developmental duration of all stages shortened;while at 32 °C, it was in adverse. At all test temperatures, the BPH on rice plants treated with 250 kg N · hm-2 had higher egg hatchability, nymphal survival and adult fecundity, and shorter developmental duration of eggs and nymphs, compared with no nitrogen fertilization, which suggested that high level nitrogen fertilization enhanced the ecological adaptability of BPH to stress conditions. There were significant interactive effects of temperature and nitrogen fertilizer on the egg hatchability, nymphal duration, and adult fecundity of BPH, implying that global warming and long-term high level application of nitrogen fertilizer could be responsible for the outbreaks of BPH in recent years. [ABSTRACT FROM AUTHOR]

Regarding the difficult key management and excessive communication overhead in the distributed group networks,KMSBoB-Key management schemes based on blockchain was proposed,featuring key management and transmitting procedure based on blockchain in distributed group networks.Meanwhile,the all-member mining process of blockchain and the MTI/CO protocol process were combined to establish a protocol of dynamically generated session key,so as to streamline key management strategies in cross-heterogeneous autonomous domains.According to simulation testing and result analysis,KMSBoB is safe and effective,with less communication overhead and higher expansibility than traditional key management schemes.

Objective: To study the effect of cluster nursing care based on 10S continuous quality improvement (CQI) on the incidence of postoperative delirium in patients with BPH., Methods: This study included 96 BPH patients undergoing transurethral resection of the prostate (TURP) in our department from August 2021 to February 2023. We randomly divided the patients into two groups of equal number to receive routine postoperative nursing care (the control group) and postoperative cluster nursing care based on the 10S DQI mode (the observation group), respectively. We recorded and compared the delirium scores of the patients at 2, 6, 12 and 24 hours after operation, their status of recovery, scores on Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) and quality of life (QOL), and incidence of complications between the two groups., Results: Compared with the controls, the patients in the observation group showed significantly lower delirium scores at 2 h (12.72±3.54 vs 10.65±2.87, P<0.05), 6 h (20.17±4.92 vs 14.19±4.64, P<0.01), 12 h (16.82±4.24 vs 10.69±3.18, P<0.01) and 24 h (13.61±2.86 vs 9.13±2.12, P<0.01) after operation, and shorter time to ambulation (［3.65±1.41］ vs ［2.84±0.83］ d, P<0.01) and time of postoperative catheterization (［6.28±1.65］ vs ［4.28±1.14］ d, P<0.01), bladder irrigation (［3.41±1.08］ vs ［2.25±0.71］ d, P<0.01) and hospitalization (［10.33±2.41］ vs ［7.82±2.06］ d, P<0.01). No statistically significant differences were observed between the two groups in either the SAS and SDS scores (P >0.05) or the QOL scores before operation (P >0.05), but the former two were dramatically decreased (P<0.01) while the latter one increased in the observation group postoperatively (P<0.01). Postoperative complications included delirium, bladder spasm, urethral pain, and secondary bleeding, with a significantly lower total incidence rate in the observation than in the control group (12.50% vs 52.08%, P<0.01)., Conclusion: Cluster nursing care based on 10S CQI can promote the postoperative recovery of BPH patients, improve their psychological status and quality of life, and reduce the incidence of delirium and complications.

Prostate cancer (PCa) is one of the common tumors in the genitourinary system, with an increasing morbidity and mortality in China. Recent studies show that autophagy plays an important pathophysiological role in many diseases, including cancers. Besides, some miRNAs are also key regulatory factors for autophagy in PCa cells, and play an important role in the development, progression, diagnosis and treatment of PCa. In-depth studies of miRNAs may contribute to the discovery of some valuable diagnostic methods and novel treatment strategies. This article reviews the progress in researches on the role of autophagy-related miRNAs in PCa, aiming to provide some reference for the diagnosis and treatment of the malignancy.

Objective: To explore the clinical manifestations, diagnosis, pathological features and treatment of small-cell carcinoma of the prostate (SCCP)., Methods: We conducted a retrospective analysis of the clinical and pathological data of 2 cases of confirmed SCCP treated from November 2017 to March 2018, and reviewed relevant literature., Results: Both the patients had the symptoms of frequent, urgent and difficult urination, with an elevated level of PSA and gradesⅡ－Ⅲ enlargement of the prostate at palpation. One underwent prostate puncture biopsy and the other received transurethral 1470 laser vaporization resection of the tumor. Postoperative pathology indicated prostate adenocarcinoma accompanied by SCCP in both of the cases. One of them was treated by etoposide-platinum (EP) chemotherapy and died of systemic multiple organ failure 20 months after diagnosis, while the other underwent endocrine therapy and has lived with tumor up to the present day., Conclusion: The incidence rate of SCCP is low, its malignancy is high, and its prognosis is poor. The average survival of the patient is about 7 to 10 months after diagnosis. Currently there is no effective management of the dissease, except by relying on the experience of the treatment of small-cell lung cancer, with chemotherapy as the main option.

Objective: To analyze the influential factors of erectile dysfunction (ED) in patients with localized prostate cancer (LPC) after radical surgery., Methods: The clinical data of 150 male patients diagnosed with LPC and normal erectile function (EF) before surgery admitted to the Department of Urology of the Eastern Theatre General Hospital from January 2021 to January 2023 were retrospectively analyzed. The EF status of the patients 6 months after surgery was assessed using the International Erectile Function Index -5(IIEF-5). Age, Gleason score, PSA level, TNM stage, preoperative International prostatic symptom score (IPSS), preoperative prostate volume, smoking index, alcohol consumption index, educational level, comorbidities, operation mode, and psychosexual state were used as influencing factors to analyze their effects on postoperative ED., Results: Of the 150 patients, 88 had ED and 62 had normal EF. Univariate analysis showed that age, preoperative IPSS, preoperative prostate volume, comorbidities and sexual and psychological status were significantly correlated with postoperative ED. Further multivariate logistic regression analysis showed that age, preoperative prostate volume, comorbidities and sexual and psychological status were independent factors influencing the occurrence of ED after RP in LPC patients., Conclusion: The recovery of sexual function of patients with localized prostate cancer after radical surgery is generally poor, and the incidence of ED is high. Its independent influencing factors include age, preoperative prostate volume, comorbidities and sexual psychological state, etc. Correct intervention of different influencing factors is required in clinical work. In order to provide a better diagnosis and treatment scheme for LPC patients undergoing radical treatment, reduce the incidence of postoperative ED and improve the quality of life of patients after surgery.

Objective: To compare the efficacy and complications of radical surgery (RP) and radical radiotherapy (RRT)., Methods: The clinical data of patients diagnosed with localized prostate cancer in General Hospital of Eastern Theater Command with RP and RRT from January 2015 to December 2019, Observed and recorded patient preoperative and postoperative PSA levels, biochemical Relapse-free Survival and clinical Relapse-free Survival,and the occurrence of hematuria, urinary incontinence, erectile dysfunction, ankylurethria, diarrhea, hemoproctia and radiocystitis., Results: A total of 150 patients with localized prostate cancer were included in this study, including 105 patients with RP and 45 patients undergoing RRT. There was no significant difference between the complication rates of hematuria, urinary incontinence, erectile dysfunction and ankylurethria(P>0.05).Patients in the RRT group had higher rates of diarrhea(20.00% vs 2.86%), hemoproctia(15.56% vs 1.90%) and radiocystitis(13.33% vs 0%) than those in the RP group, with significant differences (P<0.05). The 5-year bRFS was lower than that in the RP group (95.1% vs 90.7%), with no statistical significance (P=0.832); the 5-year cRFS in the RP group was lower than that in the RRT group (91.2% vs 89.6%), with no significant difference (P=0.971)., Conclusion: The incidence of diarrhea, hemoproctia and radiocystitis was lower in the RP group than in the RRT group, and the recurrence-free survival was not significantly different between the two groups.