Search

Langerhans cell histiocytosis (LCH) is a rare disease characterized by the proliferation of Langerhans cells and the destruction of local tissue. LCH large occurs in children, whilst incidence of the elderly population is extremely low, and there are few related studies. LCH lesions can involve multiple organs and systems, including bone tissue, lymph nodes, skin, liver, and spleen. However, it is rare that multiple soft tissues are implicated for eldly patients with LCH and present with soft tissue mass as the main manifestation. Here is a report on the clinical features, treatment and prognosis of an elderly LCH with multiple soft tissue masses as the main manifestation, in order to provide clinical reference.

Objective To investigate the clinical and pathological characteristics of KDSS with heart failure. Methods The clinical data of a child with KDSS complicated with heart failure were analyzed, and the related literature was reviewed. Results KDSS is uncommon in Kawasaki disease, and it always attended with serious performance, which can lead to circulatory failure in the acute stage. manifested as systemic circulatory failure with tachycardia, prolonged capillary filling time, chills at the end of limbs, weak pulse, reduced urine volume or disturbance of consciousness. Early identification and timely comprehensive treatment of human immunoglobulin and hormones can significantly improve the condition of shock. Conclusion KDSS is a rare but serious clinical manifestation of Kawasaki disease, and it is easy to be complicated with heart failure. Early identification and comprehensive clinical treatment are effective measures to reduce KDSS complicated with heart failure.