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Varieties of air temperature and solar activity have a close correlation with human health. The megatemperature mainly results in the increased incidence of cerebrovascular disorder (CVD). It is related to the regulatory mechanism of homeothermism. In the hypothermy environment, obvious increment of human's blood viscosity was observed, which may induce the cerebral infarction, myocardial infarct or coronary heart disease. Not only have solar activities a close relationship with the incidences of plague and epidemic cerebrospinal meningitis, but also high correlation with onco-genesis and infant natality and mortality. UV-A and UV-B may cause skin destructions. The measures and further study on lessening hazards of climate change were discussed in this article.