Search

Objective To investigate the prevalence, harm and risk factors of hyperuricemia (HUA) among middle-aged and elderly residents in Tianning District of Changzhou City, Jiangsu Province. Methods From January to May 2018, a total of 6110 residents aged over fifty years were randomly selected from two communities in Tianning District of Changzhou City, Jiangsu Province, and then arranged to take part in a questionnaire and physical examination. Their fasting venous blood were extracted for detection of serum uric acid, creatinine, urea nitrogen, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglyceride (TG). The prevalence of HUA in all the subjects and the clinical features of HUA patients were investigated, the factors affecting HUA were analyzed with monofactorial independent-samples t test and multivariate logistic regression analysis, and the relationship of bad habits and comorbidities to HUA was analyzed with monofactorial independent-samples t test. Results Rejecting the subjects with incomplete data, 5848 subjects were involved in present investigation, among them 993 were HUA patients (17.0%). Compared with those with normal uric acid, the proportion of males [50.5%(501/993) vs. 45.4%(2206/4855), P=0.004] was higher, the average age [(67.9±9.4) vs. (66.6±8.7), P