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Background The incidence rate of stroke is high and the risk of recurrence is substantial. Most stroke patients need to transition to home after treatment, and the experience during this period is complex. Therefore, there is an urgent need to comprehensively understand experiences and feelings of patients during hospital to home transition through Meta-integration. Objective To systematically evaluate qualitative studies on stroke patients' hospital to home transition experiences. Methods A computerized search was undertaken for qualitative studies on the hospital to home transition experience of stroke patients in the PubMed, Web of Science, Scopus, Embase, CINAHL, PsycINFO, CNKI, and Wanfang Data from inception to July 11, 2023. The quality of the final included literature was evaluated using the Joanna Briggs Institute (JBI) Quality Evaluation Criteria for Qualitative Research (2016), Australia, and the results were combined using a pooled integration approach. Results A total of 13 studies were included, and 46 findings were distilled and categorized into 7 categories, yielding three final integrative findings: dynamic changes in the physical and psychosocial dimensions have interactive effects; a strong need for holistic caregiving; and active coping with illness and gradual transition to a new life norm. Conclusion During the period of transition from hospital to home, stroke patients face complex physical and mental challenges as well as multi-level care needs. Healthcare providers should pay attention to the real experiences and unmet needs of stroke patients throughout the hospital to home transition, provide holistic and continuous care services, and facilitate the comprehensive physical, psychological and social transition for patients.

Background With China's aging population, the incidence of stroke is increasing year by year, and the high disability rate places a significant burden on patients, families, and society. It is extremely important to strengthen the rehabilitation self-efficacy of home-based stroke patients in order to assist them return to society as soon as feasible. Currently, less emphasis is being paid to the influence of environmental factors on rehabilitation self-efficacy in stroke. Objective To investigate the current status of rehabilitation self-efficacy of stroke patients in community, and explore the influence of different environmental factors on rehabilitation self-efficacy of stroke patients. Methods Using convenience sampling, from December 2019 to September 2020, 262 stroke patients in the subordinate communities of 4 community health service centers in Zhengzhou, Henan Province were enrolled in the survey. The Demographic Information Questionnaire was used to collect general data, the Modified Rankin Scale was used to assess the physical function of stroke patients, the Measure of Stroke Environment was used to assess the current situation of stroke environment, and the Chinese Version of Stroke Self-efficacy Questionnaire was used to assess the rehabilitation self-efficacy of stroke patients. The effects of various environmental factors on rehabilitation self-efficacy of stroke patients were investigated by hierarchical regression analysis. Results A total of 285 questionnaires were distributed, a total of 262 valid questionnaires were collected, with an effective response rate of 91.93%. The rehabilitation self-efficacy score of 262 stroke patients was (76.1±26.3). Receptivity, physical environment and communication environment accounted for 30.9% of the total variation in rehabilitation self-efficacy (P

Background Previous studies have found that 25%-85% of stroke patients develop post-stroke fatigue (PSF) , and continuous feeling of fatigue seriously affects patients' daily life and rehabilitation process. Therefore, it is urgent to understand the psychological experience and needs of such patients. However, the results of previous single qualitative studies may not be representative. Objective To systematically review and integrate qualitative studies on the fatigue experience of patients with PSF, so as to provide a reference for the construction of management strategies for PSF patients. Methods PsycINFO, PubMed, Web of Science, CINAHL, Cochrane Library, Scopus, Joanna Briggs Institute (JBI) Evidence-Based Health Care database, CNKI, Wanfang Data, VIP, CBM were searched by computer to screen qualitative studies on fatigue experience of patients with PSF from inception to July 5, 2023. JBI Critical Appraisal Tool for qualitative studies in Australia was used to evaluate the quality of included literature, and Meta-synthesis was performed to integrate results. Results A total of 10 papers were included, and 22 primary outcomes were distilled, grouped into 8 categories, and synthesized into 4 integrated outcomes, including significant lack of cognition of PSF; intricate negative physical and psychological experience; different self-regulation of PSF and multiple needs for PSF rehabilitation. Conclusion PSF patients have insufficient cognition of fatigue with significant negative physical and psychological experience. Therefore, PSF patients should be identified and screened at an early stage with strengthened fatigue education and personalized fatigue management strategies. Emphasis should also be placed on the role of community and family in the management of fatigue, so that they can work together with healthcare professionals to provide a favorable rehabilitation environment for PSF patients.

BackgroundAs a kind of unhealthy lifestyle, sedentary behavior is closely related to poor prognosis of stroke patients. So it is of great significance to understand sedentary behavior prevalence in stroke patients, and to formulate intervention measures based on its influencing factors.ObjectiveTo investigate sedentary behavior prevalence and associated factors in stroke patients in the community, providing a reference for the development of targeted interventions.MethodsFrom August to December 2020, by use of convenience sampling, 230 eligible community stroke patients from Zhengzhou (including individuals who underwent reexaminations in neurology and neurosurgery clinics of three grade A tertiary hospitals and those who were from three communities) were selected to attend a survey using Demographic Questionnaire, Sedentary Behavior Questionnaire, the Chinese version of Fatigue Severity Scale, the Chinese version of Stroke Self-Efficacy Questionnaire, and Social Support Scale. Binary Logistic regression analysis was used to explore associated factors of sedentary behavior.ResultsThe survey achieved a response rate of 97.8%. The average daily sedentary time of the respondents was (7.10±2.75) hours, and 179 cases (79.6%) had daily sedentary time ≥5 hours. The daily sedentary time differed significantly by age, living in rural or urban areas, education level, number of complications, number of chronic diseases and fatigue (P

Objective: Tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) have been reported to be effective in the treatment of esophageal and esophagogastric junction cancers. The aim of this study was to detect the frequency of EGFR mutation and expression in Chinese patients with esophageal, esophagogastric junction and gastric cancers, and to clarify the value of EGFR mutation and expression in predicting the efficacy of TKI in the treatment of these tumors., Methods: In this study, 180 tumor samples with histologically confirmed esophageal cancer (39 cases), cancer of the esophagogastric junction (92 cases) and gastric cancer (49 cases) were collected. Twenty-nine different EGFR mutations in exons 18-21 were assessed by real-time PCR-optimized oligonucleotide probe method. EGFR protein expression was evaluated by immunohistochemistry (IHC) in 89 tumor samples., Results: The mutation analysis for EGFR (exons 18-21) showed no mutations in any of the hotspots of the gene in the 180 tumor samples analyzed. EGFR expression was negative in 12 tumor samples, 1+ in 31 tumor samples, 2+ in 24 tumor samples, and 3+ in 22 tumor samples. EGFR expression was 2+ or 3+ in 12 (92.3%) of the 13 esophageal squamous cell carcinomas, 29 (47.5%) of the 61 esophagogastric junction cancers, and 5 (33.3%) of the 15 gastric adenocarcinomas., Conclusions: Our results indicate that EGFR mutation in exons 18-21 is absent in the examined samples of esophageal, esophagogastric junction and gastric cancers. More studies are warranted to explore the predictive biological markers for the therapeutic response to EGFR TKI.