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To explore the effect of early pupil dilation after surgery on ocular hemodynamics in patients with diabetic retinopathy (DR) complicated with cataract, and to analyze the related factors affecting pupil diameter up to standard after dilation. 150 patients with DR complicated with cataract who were treated in cataract surgery in The First Affiliated Hospital of Hebei North University from January 2018 to January 2022 were selected, the patients were evenly divided into control group and observation group by random number table method, two groups were given compound topicamide eye drops to dilate pupil after surgery, pupils were dilated once on 7d, and 14d after surgery in the control group, early pupil which beganing to dilate pupil once a day on the next day after surgery were dilated in the observation group. The changes and differences of ocular after surgery hemodynamics between the two groups were compared. According to whether the pupil diameter reaches the standard after pupil dilation on the 14th day after operation, the patients were divided into the standard group (pupil diameter ≥5 mm) and the non-standard group (pupil diameter＜5 mm), clinical data of patients were collected, multivariate Logistic regression was used to analyze the factors affecting whether the pupil diameter reached the standard after pupil dilation. The central retinal artery, short posterior ciliary artery end diastolic flow velocity (EDV) and peak systolic velocity (PSV) of the observation group increased 14 d after surgery compared with 7d after surgery (P<0.05), resistance index decreased compared with 7 d after operation (P<0.05), EDV and PSV of central retinal artery and short posterior ciliary artery were higher than those of control group at 7 d and 14 d after surgery (P<0.05), RI was lower than that of control group (P<0.05). The pupil dilation time of observation group on 14 d after surgery was shorter than that on 7 d after surgery (P<0.05), the pupil diameter after pupil dilation increased compared with 7 d after operation (P<0.05), the pupil dilation time of the observation group was shorter than that of the control group on the 7d and 14d after operation (P<0.05), and the pupil diameter after pupil dilation was larger than that of the control group (P<0.05). The duration of diabetes > 10 years and the DR proliferative period were the risk factors affecting pupil diameter after pupil dilation (P<0.05), and early postoperative dilation was a protective factor (P<0.05). In patients with cataract complicated with DR, early postoperative dilation can shorten the duration of pupil dilation of pupil, improve ocular hemodynamics, and increase pupil diameter after pupil dilation. The duration of diabetes, the severity of diabetic retinopathy and the timing of dilate pupils after surgery are the influencing factors of pupil diameter after pupil dilation. [ABSTRACT FROM AUTHOR]

Objective: In order to improve the efficiency of treatment, this study compared catheter contact thrombolysis in patients with iliac vein compression syndrome and deep vein thrombosis at the same time as balloon dilatation + stent treatment plan and staged treatment plan. Methods: Sixty-five patients with iliac vein compression syndrome combined with deep vein thrombosis of the lower extremities were taken as the research objects. According to the treatment method, they were divided into study group and control group. Thirty-two patients in the study group received catheter-contact thrombolysis and balloon dilatation + stent therapy at the same time; 33 patients in the control group received catheter-contact thrombolysis and balloon dilatation+ stent therapy. The patient's thigh circumference, calf circumference, vascular patency score, surgical indicators (hospitalization time, hospitalization times, thrombolysis time and puncture times), complications (thrombosis recurrence, bleeding, and pulmonary embolism) and sequelae of deep vein thrombosis are used as indicators. Results: The thigh circumference, calf circumference and venous patency scores of the two groups of patients were not significantly different before treatment (P>0.05). After treatment, the thigh circumference, calf circumference and venous patency scores of the two groups were significantly improved (P<0.05). There was no significant difference in various indicators between the two (P>0.05). The length of hospitalization, the number of hospitalizations, the time of thrombolysis and the number of punctures in the study group were significantly lower than those in the control group (P<0.05). There were 0 cases of thrombosis recurrence in the study group and 4 cases of thrombosis recurrence in the control group (P＜0.05). There were 1 bleeding in the study group, 0 pulmonary embolism, 2 bleeding in the control group, and 0 pulmonary embolism. There was no significant difference in bleeding and pulmonary embolism between the two groups(P>0.05). The incidence of PTS in the study group was 6.25 %, which was significantly lower than 18.18 % in the control group (P<0.05). Conclusions: Catheter contact thrombolysis at the same time balloon dilatation + stent treatment program has a good effect on iliac vein compression syndrome with deep vein thrombosis of lower limbs. [ABSTRACT FROM AUTHOR]

To explore the Endoscopic sphincterotomy combined with different durations of endoscopic papillary balloon dilatation in patients with common bile duct stones. A total of 92 patients with common bile duct stones who underwent EST combined with EPBD in our hospital from January 2018 to December 2018 were selected as the study subjects. They were divided into group A according to the intraoperative balloon dilation time (46 patients, dilatation expansion time 20 s), group B (46 patients, dilatation expansion time 40 s), compared the two groups of patients with a net stone rate, mechanical lithotripsy rate, operation time and X-ray exposure time, compared the two groups of patients with liver function indicators before and after surgery The blood amylase at 12 hours after operation was compared with the incidence of complications such as pancreatitis, gastrointestinal bleeding, biliary infection, and perforation in the two groups. (1) The comparison showed that there was no statistically significant difference between the two groups of patients in the rate of clean stones, mechanical lithotripsy, operating time, X-ray exposure time, and 12 h blood amylase (P>0.05). (2) The differences in TBIL, ALT, and ALP between the two groups of patients before surgery were not statistically significant (P>0.05). The above indicators in the two groups of patients showed a significant decrease compared with that before treatment, but there was no difference between the groups(P>0.05). (3) The incidence of various postoperative complications in group A was 4.35 % (2/46), and the incidence of various postoperative complications in group B was 17.39 %(8/46). The difference between the two groups was statistically significant (P<0.05). EST combined with EPBD has a good therapeutic effect on common bile duct stones. Different balloon inflation times during the operation will not affect the success rate and operation time, but long-term expansion will increase the risk of postoperative bleeding. In the case of surgery, try to control the balloon dilation time during the operation. [ABSTRACT FROM AUTHOR]

Objective: To study the effect of continuous analgesia on delivery outcome and neonatal score of parturients. Methods: From July 2018 to July 2019, 101 parturients with epidural analgesia in our hospital from July 2018 to July 2019 were randomly divided into two groups. When the exact analgesic effect was achieved, after entering the second stage of labor, 51 parturients in the observation group used 0.4 ug/mL sufentanil and 0.08 % ropivacaine for continuous analgesia delivery. 50 parturients in the control group used physiological saline the local anesthetics in the pump after the uterine cavity was opened, until the end of delivery. Compare the rates of oxytocin use, uterine dilatation and the number of times the epidural self-controlled analgesia pump is pressed during the first and second stages of labor, delivery methods, newborn body weight, umbilical blood pH, and min and 5 min Apgar scores, VAS scores during maternal repair of the perineum, and maternal satisfaction scores for analgesia in the second stage of labor. There was no significant difference in the use rate of oxytocin, dilatation of the uterine orifice and the number of times of pressing the epidural self-controlled analgesia pump in the first and second stages of labor, the method of delivery (cesarean delivery, device assisted delivery, natural delivery rate), analgesia time in the first stage of labor, and first and second stage of labor between the two groups (P>0.05). Results: There was no significant difference in body weight, umbilical artery blood pH value, and the proportion of newborns with Apgar scores less than 8 in 1 min and 5 min after birth between the two groups (P>0.05). The VAS score of the observation group when repairing the perineum was significantly lower than that of the control group (P<0.05), and the satisfaction score of the women during the second stage of labor the observation group was significantly higher than that of the control group (P<0.05). Conclusion: Continuous analgesic delivery has no significant effect on maternal delivery outcome and neonatal scores, but it can significantly increase maternal satisfaction with analgesia in the second stage of labor and with analgesia when repairing the perineum. [ABSTRACT FROM AUTHOR]