In order to solve the problems in the design of HFETR spent fuel storage rack, such as slow iterative design speed, long seismic analysis time and difficult multirack analysis, a combination of parameterization method and superelement method was proposed to analyze the HFETR spent fuel storage rack. Firstly, a finite element model for seismic analysis of HFETR spent fuel storage rack was established based on superelement method, and the calculation accuracy of the superelement model was verified by modal analysis. Then, APDL program and VB platform were used to parameterize the establishment and calculation of the finite element model of the rack, and the special analysis interface of the rack was established. Through this interface, the size and boundary conditions of the rack can be quickly modified, and the finite element model, analysis type and background calculation can be established quickly, which simplifies the modeling and analysis process of the iterative design of the rack. Finally, the multi-rack seismic analysis of HFETR spent fuel storage rack was carried out by using time-history analysis method. Two seismic working conditions (OBE and SSE) and three loading conditions (full load, half load and no load) were taken into account, altogether six combinations. In this paper, the performance of stress, slip and dumping of HFETR spent fuel storage rack under six combinations was analyzed. The results show that the stress of the rack meets the requirements under the six conditions, and the maximum stress of the base is generated under the condition of half load and SSE. In the six conditions, the slip displacement of the rack is small and no collision will occur. The slip amplitude of the rack is full load, half load and no load from small to large. In other words, the slip amplitude of the rack tends to decrease with the increase of the loading capacity of the spent fuel assembly. The designed rack will not topple under the six conditions. The dumping limit of the rack is the minimum at half load, and the height of the jump is the maximum at half load in the earthquake, so the possibility of the toppling is the maximum at half load in the earthquake, and the half load should be paid more attention to in the analysis of the toppling of the rack. In general, the seismic performance of the designed HFETR rack meets the requirements. The parameterizationsuperelement method can be applied to the seismic analysis of multiple racks and provide convenience for the iterative design of spent fuel storage racks.