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In some engineering applications and accidents, the detonation performance of explosives may change if subjected to multiple shocks and releases. Therefore, an experimental loading device with multiple shocks and releases is needed in order to study the detonation response of explosives under complex loads. In this paper, an experimental detonation loading device that can achieve complete release of shock-releasereshock is proposed and designed. The device is optimized through numerical simulations, and the accuracy of the numerical simulation is validated by the corresponding experiments. The results indicate that the designed detonation loading device can achieve complete release of shock-release-reshock loading procesure of TATB-based insensitive explosives, where the detonation loading device drives tungsten magnesium double-layer flyers. The design provides a new experimental technique for further study on the detonation response of explosives under complex loads and multiple shocks. [ABSTRACT FROM AUTHOR]