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Chronic obstructive pulmonary disease (COPD) tends to cause skeletal muscle dysfunction, leading to muscle atrophy. When respiratory muscles are involved, it further exacerbates the progression of COPD and affects patient prognosis, creating a vicious cycle. Quantitative MRI not only avoids radiation damage to patients but also accurately measures changes in muscle morphology and composition. This aids in the early detection of decreased respiratory muscle quality in COPD patients. This article provides a review of the research progress on the quantitative MRI assessment of respiratory muscle dysfunction in COPD patients. [ABSTRACT FROM AUTHOR]

Objective To investigate the distribution characteristics as well as T1-,T2-and T2*-mapping MR quantitation of different grades of cartilage injury in knee osteoarthritis（OA）.Methods MRI of 73 knee joints with 213 cartilage lesions was retrospectively analyzed.The arthroscopic results were used as gold standard to compare the distribution and differences of T1-,T2-,and T2*-mapping values on MRI of different grades of cartilage lesions.Results Grade I and II cartilage lesions were significantly more common in the patellofemoral joint surface than that in the medial and lateral femorotibial joint surfaces（P<0.05）.There was no difference in the distribution of lesion grades in the two cartilage subareas of the same articular surfaces（P>0.05）.The accuracy of T2-and T2*-mapping was significantly higher than that of T1-mapping（P<0.05） for grade I-III lesions without significant difference in accuracy for grade Ⅳ lesions（P>0.05）.There was no significant difference between T2-and T2*-mapping for the lesion grades（P>0.05）.The Kappa value of T2*-mapping was the highest（0.663）.The values of T1-,T2-and T2*-mapping increased significantly from grade I to grade II lesions with less increase in grade III lesions.The changes of T2*-mapping value were more obvious than that of T2-mapping.There was no significant difference in T1-mapping values（P>0.05） of different grade lesions whereas there was significant difference in T2-and T2*-mapping values（P<0.05）.Conclusion The distribution characteristics and MRI quantitative imaging have good diagnostic value for distinguishing different grades of cartilage lesions in knee OA. [ABSTRACT FROM AUTHOR]