Search

Copyright of China Condiment is the property of China Condiment and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Hebei University of Science & Technology is the property of Hebei University of Science & Technology, Journal of Hebei University of Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The concept of reference sample was put forward in the Guidance on CMC of Traditional Chinese Medicine Compound Preparations Developed from Catalogued Ancient Classical Prescriptions(Interim). The research on reference sample is a key link in the research and development of traditional Chinese medicine(TCM) compound prescriptions from catalogued ancient classical prescriptions(known as Category 3.1 TCM). This paper discusses the content of research on reference sample by analyzing the characteristics of Category 3.1 TCM and the purpose of research on reference sample. Furthermore, suggestions on the research of reference sample are proposed according to the development and evaluation practice of Category 3.1 TCM and research achievements of TCM regulatory science, aiming to provide reference for colleagues in this industry.

Objective To study the preparation technology and quality of cefotiam hexetil hydrochloride tablet. Methods The disintegration time limit and dissolution of drug were taken as the main index. The original piece of reference was used to optimize the prescription process and preliminary study on its quality . Results The best prescription was determined by experiments : cefotiam hexetil hydrochloride tablets were prepared by dry granulation with anhydrous citric acid, alpha-cyclodextrin， microcrystalline cellulose,hydroxypropyl cellulose, silica,magnesium stearate and film-coated premix (gastric-soluble) . The indexes of cefotiam hexetil hydrochloride tablet conformed to the Japanese Pharmaceutical Bureau Prescription (JPXV) standard. Conclusion The preparation technology of cefotiam hexetil hydrochloride tablet was feasible and the product had good stability. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Shanghai Physical Education Institute / Shanghai Tiyu Xueyuan Xuebao is the property of Shanghai Physical Education Institute and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To prepare aceclofenac pellets by centrifugal granulation. Using 90 ~100 g of starch pellets as the core pellets, 100 g of aceclofenac mixed with 50 g of microcrystalline cellulose (MCC) and 4 g talc, methyl cellulose (HPMC) as binder, the aceclofenac pellets were prepared by centrifugal granulation. And evaluate the quality of the pellets. The aceclofenac pellets had high yield and less losses,the pellets had a partical size of 0. 70~0. 88 mm(18~24 mesh)and had uniform particle size, the moisture,drug content and dissolution meet the requirement. Aceclofenac pellets were prepared by the process of centrifugal granulation. The preparation prescription and process parameters were optimized by single factor method, and the pellets meet the standard requirements. [ABSTRACT FROM AUTHOR]

Thin layer chromatography, high performance liquid chromatography and multivariate statistical analysis were integrated in current study to provide a basis for the quality evaluation and the standard improvement of Paridis Rhizoma(Chinese name: Chong-lou). The results demonstrated that the primary saponins in the two authorized sources of Paridis Rhizoma were polyphyllinsⅠ, Ⅱ and Ⅶ, while the rhizome of Trillium tschonoskii an adulterant of Paridis Rhizoma was rich of polyphyllin Ⅵ. Therefore, the apparent content of polyphyllin Ⅵ plays a determinant role towards the source authentication of raw materials and decoction slices of Paridis Rhizoma, whose adulterants frequently occur in the market. Moreover, the contents of polyphyllin Ⅵ in the two authorized sources could meet the requirements of Chinese Pharmacopoeia. Therefore, we suggested that polyphyllin Ⅵ should not be omitted from the quality standard of Paridis Rhizoma in the Chinese Pharmacopoeia, and on the other side, polyphyllinsⅠ, Ⅱ and Ⅶ should be the eligible quality indicators. The study aims to sound information and evidences for the quality evaluation of Paridis Rhizoma, and also to provide a theoretical basis for the standard revision of Paridis Rhizoma in the future Chinese Pharmacopoeia.

To prepare aceclofenac pellets by centrifugal granulation. Using 90~100 g of starch pellets as the core pellets,100 g of aceclofenac mixed with 50 g of microcrystalline cellulose(MCC) and 4 g talc, methyl cellulose (HPMC) as binder,the aceclofenac pellets were prepared by centrifugal granulation .And evaluate the quality of the pellets. The aceclofenac pellets had high yield and less losses,the pellets had a partical size of 0.70~0.88 mm（18~24 mesh）and had uniform particle size .the moisture ,drug content and dissolution meet the requirement . Aceclofenac pellets were prepared by the process of centrifugal granulation .The preparation prescription and process parameters were optimized by single factor method .and the pellets meet the standard requirements.