1. 术前超声引导下腰方肌阻滞联合全身麻醉对肾移植患者术后血清 应激反应和疼痛相关指标的影响.
- Author
-
李 洪, 周汝虹, 王 东, 杨旭亮, 何爱梅, 曾长洲, 伍江明, and 晏 强
- Subjects
- *
SUBSTANCE P , *KIDNEY transplantation , *BLOOD sugar , *DINOPROSTONE , *RANDOM numbers , *GENERAL anesthesia , *PATIENT-controlled analgesia - Abstract
Objective: To investigate the effect of preoperative ultrasound-guided quadratus lumborum block (QLB) combined with general anesthesia on serum stress response and pain related indexes in patients with renal transplantation. Methods: 82 patients undergoing renal transplantation in our hospital from September 2019 to August 2021 were selected as the observation objects. According to the random number table method, they were divided into group A and group B, 41 cases respectively. Group A was given general anesthesia, and group B was given preoperative ultrasound-guided QLB combined general anesthesia. The resting visual pain simulation (VAS) score, the dosage of sufentanil in patient-controlled intravenous analgesia, the number of effective compressions were compared between the two groups, the changes of serum stress response and pain related indexes were compared between the two groups, and the incidence of adverse reactions were compared between the two groups. Results: The resting VAS scores at 6 h, 12 h, 24 h and 48 h after operation in group B were lower than those in group A(P<0.05). The dosage of sufentanil in patient-controlled intravenous analgesia in group B was less than that in group A, and the number of effective compressions was less than that in group A (P<0.05). Blood glucose (Glu) and cortisol (Cor) in group B after extubation and 24 h after operation were lower than those in group A (P<0.05). Substance P (SP), prostaglandin E2 (PGE2) and serotonin (5-HT) increased 24 h after operation in the two groups, but group B was lower than group A (P<0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P<0.05). Conclusion: Preoperative ultrasound-guided QLB combined with general anesthesia for patients with renal transplantation can effectively reduce pain and stress response, reduce the dosage of sufentanil in patient-controlled intravenous analgesia and the number of effective compressions, and do not increase the incidence of adverse reactions. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF