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ObjectiveTo understand the pneumococcal vaccination status and its influencing factors among young and middle-aged populations, and provide reference for promoting pneumococcal vaccination. MethodsFrom May to August 2023, a multi-stage random cluster sampling method was used to select 5 928 residents aged 19 – 59 years old from Nanchang city in Jiangxi province, Changsha city in Hunan province, and Kunming city in Yunnan province for an online questionnaire survey on pneumococcal vaccination status. ResultsAmong the 4 895 young and middle-aged people finally included in the analysis, only 833 had received pneumococcal vaccine in the past 5 years, with a pneumococcal vaccine uptake rate of 17.02%; multivariate unconditional logistic regression analysis showed that the pneumococcal vaccine uptake rates were higher among those aged 45 – 59 years old, agriculture, forestry, animal husbandry and fishery production personnel, professional and technical personnel, smokers, those with general knowledge of pneumococcal diseases and vaccines, and those with general and good trust in pneumococcal vaccines, while the uptake rates were lower among those with high school/technical secondary school education or above and office clerks and related personnel; the top three reasons for pneumococcal vaccination among young and middle-aged people were disease prevention (75.87%), protecting family and colleagues (57.38%), and government and health administration recommending vaccination (43.22%), while the top three reasons for not receiving pneumococcal vaccine were worrying about adverse reactions after vaccination (42.22%), no time for vaccination (28.19%), and believing that the vaccine had limited effectiveness (25.11%), and the top three factors most likely to change vaccination willingness were free/discounted vaccines (46.63%), worrying about the impact of pneumonia infection on family and colleagues (46.53%), and government and health administration recommending vaccination (45.89%). ConclusionThe pneumococcal vaccine uptake rate among young and middle-aged populations was low, and age, education level, occupation, smoking status, knowledge of pneumococcal diseases and vaccines, and trust in vaccines was the main influencing factors for pneumococcal vaccination in this population. Comprehensive policy measures, especially the introduction of preferential policies related to pneumococcal vaccines, should be adopted to promote vaccination.

ObjectiveTo examine the coverage and influencing factors of influenza and pneumococcal vaccines among urban and rural residents aged ≥ 50 years in Zhejiang province for promoting the vaccination of the two vaccines in the population. MethodsA face-to-face interview with a self-designed questionnaire was conducted during June of 2022 among 2 200 residents aged 50 years above recruited in 35 communities/villages of 7 districts/counties, Zhejiang province. The coverage of influenza and pneumococcal vaccination were statistically described and unconditional multivariate logistic regression model was used to analyze main influencing factors of influenza and pneumococcal vaccination. ResultsOf the 2100 residents ultimately included in the analysis, 776 (36.95%) and 116 (5.52%) reported having influenza vaccination in past one year and pneumococcal vaccination in past five years, respectively. The results of unconditional multivariate logistic regression analysis showed that the residents having the education of high school and above, with influenza vaccine-related awareness, being able to have free of charge vaccination, and ever receiving doctor’s relevant recommendation were more likely to have influenza vaccination and that the residents being able to have pneumococcal vaccination free of charge and ever receiving doctor’s relevant recommendation were more likely to have pneumococcal vaccination. The vaccinees of influenza and pneumococcal vaccine reported following similar vaccination motivations: receiving vaccination notification from community health centers (reported by 590 [76.03%] and 85 [73.28%] of the vaccinees), being promoted by suggestions of family members (400 [51.55%] and 67 [57.76%]), and self-intention to prevent the diseases (350 [45.49%] and 51 [43.97%]); while, the non-vaccinees of influenza and pneumococcal vaccine also reported similar reasons for not having the vaccinations, including without knowledge about influenza or pneumococcal vaccine (reported by 816 [61.63%] and 1 334 [63.52%] of the non-vaccinees), being worried about side effects of the vaccine (321 [24.24%] and 442 [22.28%]), and not perceiving vaccination necessity (296 [22.36%] and 472 [22.48%]). ConclusionThe vaccination rate of influenza and pneumococcal vaccine are relatively low and mainly influenced by the accessibility of vaccinations free of charge and recommendation on the vaccinations from medical professionals among residents aged ≥ 50 in Zhejiang province.

Organ transplant recipients are at a high risk of infection with high hospitalization rate, critical rate and fatality, due to low immune function caused by taking immunosuppressants for a period of long time after organ transplantation. Currently, vaccination is recognized as an effective approach to prevent infection. Organ transplant recipients may be vaccinated according to individual conditions. However, the sensitivity to vaccines may decline in organ transplant recipients. The types, methods and timing of vaccination have constantly been the hot spots of clinical trials. In this article, the general principles, specific vaccines and SARS-CoV-2 vaccines of vaccination in organ transplant recipients were briefly reviewed, aiming to provide reference for the vaccination of organ transplant recipients. Moreover, current status of SARS-CoV-2 vaccination for organ transplant recipients was illustrated under the global outbreak of novel coronavirus pneumonia pandemic. [ABSTRACT FROM AUTHOR]