[Objective] The study was conducted to evaluate the difference of Cd-As absorption and accumulation by different rice varieties in cadmium (Cd) and arsenic (As) co-contaminated soils, in order to provide theoretical basis for safe production and utilization of rice in the region. [Method] The experiment site was located at Dongchuang district of Kunming city, Yunnan province. A field experiment was used to carry out this investigation; The experiment consisted of ten treatments, including Indica Hybrid Rice (Zhongzheyou 8, Zhongzheyou 10, Zhongzheyou 1, Qingyou 676, Minhongliangyou 177),Conventional Indica Rice (Yunhangjing 3, Yunhanghong 1), Conventional Japonica Rice (Yunhangjing 2, Yunhangjing 3, Yunhangjing 7).Plants were sampled during the mature stage, then rice agronomic traits and Cd-As accumulation characteristics were analyzed in different rice cultivars. [Result] There were significant differences in the agronomic traits and Cd-As accumulation characteristics in different rice cultivars. Among them, the values of maximum rice yield, plant height, 1000-grain weight and seed setting rate were 2.91, 1.17, 1.40 and 1.24 times of their minimum, respectively. The values of maximum biomass shoots and roots were 2.12 and 2.47 times of their minimum, respectively. The values of maximum Cd and As contents in the roots, stems and leaves, chaffs and brown rice were 2.33, 3.50, 1.40 and 4.00 times and 2.03, 3.50, 1.40 and 4.00 times of their minimum, respectively. The values of maximum Cd and As accumulation in the roots, stems and leaves, chaffs and brown rice were 4.45, 3.27, 3.53 and 12.06 times and 2.51, 1.81, 3.02 and 3.70 times of their minimum, respectively. The Cd and As transport coefficient was as the following: TFrice/stem>TFrice/chaff>TFstem/root and TFstem/root> TFrice/chaff>TFrice/stem in rice. Among all rice cultivars, Zhongzheyou 8 had high agronomic characters, its brown rice Cd and As accumulation was also high, while Yunhangjing 2 had low agronomic characters, its brown rice Cd and As accumulation was the lowest. Correlation analysis showed that the yield was extremely significantly positively correlated with the brown rice Cd content, while the yield was extremely significantly negatively correlated with the brown rice As content. The brown rice Cd content was extremely significantly positively correlated with TFrice/stem and TFrice/chaff, while the chaffs As content was extremely significantly negatively correlated with TFrice/stem and TFrice/chaff, the brown rice As content was not significantly correlated with TFstem/root, TFrice/stem, and TFrice/chaff and the brown rice Cd content was not significantly correlated with brown rice As content. [Conclusion] In the long-term flooded soil, the Cd activity was low and the As activity was high, but the Cd transport capacity in different parts of rice was higher than that of the As transport capacity of planting hybrid indica rice varieties, Zhongzheyou 8 with high yield was good for growing in soils without heavy metal contamination, while conventional japonica rice Yunhangjing 2 should be used as the best rice variety in Cd and As co-contaminated polluted soils. [ABSTRACT FROM AUTHOR]