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In order to halance the security requirements and resource costs of the three party authentication protocols for radio frequency identification(RFID), this paper proposed a protocol based on Chebyshev chaotic mapping and physical unclonable function(PUF), taking advantage of the semi-gmap property and chaotic property of Chebyshev polynomials. It used Chebyshev chaotic mapping to achieve secret sharing among tags, readers, and servers, and used random numbers to achieve freshness of each session which could resist replay attack, and also to realize the anonymity of readers and tags. It used the PUF function to achieve the authentication of the label and to resist physical cloning attacks. Security analysis shows that this protoenl can effec tively resist various malicious attacks such as tracking, replay, physical cloning, and de-synchronization attacks. Moreover, it verified the security properties of the protocol using formal methods, including BAN Ingie and Scyther tool. Compared with recent studies, this protocol compensates for the security deficiencies of similar RFID protocols, balancing harthcare costs as much as possible while meeting various security attribute requirements, and still fitting the limited hardware resources of RFID. It is suitable for third-party authentication scenarios in RFID. [ABSTRACT FROM AUTHOR]

The people of Hongzhou, represented by eminent monk Matsu Daoyi in the Tang Dynasty, actively practiced the Buddhist concept of " Ordinary mind is the Tao ", innovated and developed the Zen tea culture since the Six Dynasties, especially the Northern Sect Zen, and guided Zen tea from focusing on physical function to physical, spiritual unity with spirituality as the priority. This greatly enhanced the connotation and realm of Zen tea culture, and the quote of "going for tea" increasingly became a major Zen phrase and Zen method popular in the jungle. Matsu Hongzhou Sect effectively promoted the formal establishment and popularization of jungle Zen tea, which became one of the key parts to the practice of Sinicization of Buddhism. Its influence can be described as profound and huge. [ABSTRACT FROM AUTHOR]

Objective To observe the therapeutic effect of 3D-printed titanium alloy sternum in the postoperative reconstruction of sternum in the patients with failed conventional titanium plate stermal reconstruction, and to provide the evidence for the treatment of such disease. Methods The clinical data of one patient with malignant sternum tumor were collected. The patient’s operation process was observed, and the recovery of the patient’s physical function was followed up. The relevant literatures were reviewed and summarized. Results One patient, a 59-year-old male, presented with sternum pain without obvious cause and received the chest computed tomography (CT) examination, which indicated a space-occupying lesion in the sternum. The patient was admitted with the diagnosis of “sternal tumor” and underwent partial sternectomy and conventional titanium plate placement in 2017. Subsequently, the patient experienced severe restriction of limb movement, titanium plate fracture, and deformation 1 year after operation. In 2019, 3D-printed titanium alloy sternum implantation was performed to repair the sternum defect and reconstruct the thoracic cage.Compared with before operation, the patient’s limb movement gradually recovered, ranging from passive to active activities, and the normal range of motion of the shoulder joint was gradually improved significantly after operation. In 2020, due to the thin subcutaneous fat and stable formation of fibrous connective tissue, the planned operation was performed to remove the 3D-printed titanium alloy sternal rib clavicle plate. The postoperative recovery of the patient was smooth, and the upper limb activity was normal and the quality of life was significantly improved.The prognosis was good. Conclusion The application of 3D-printed titanium alloy sternum enables precise personalized treatment, which is superior to the conventional titanium plate, and it can ensure the anatomical restoration and reduce the occurrence of complications in the patients. [ABSTRACT FROM AUTHOR]

Objective To evaluate the clinical efficacy of an integration of traditional and western medicine rehabilitation program in the treatment of patients with post-COVID-19 syndrome. Methods A total of 115 patients recovering from COVID-19 admitted to Nanjing Lishui District Hospital of Traditional Chinese Medicine and Yangzhou Second People’ s Hospital were randomly divided into the treatment group(57 patients) and the control group (58 patients). The treatment group was treated with an integration of traditional and western medicine rehabilitation program, including Chinese medicine (Jiangpi Yangfei Formula for syndrome of qi deficiency of lung and spleen, and Yiqi Yangyin Formula for syndrome of deficiency of both qi and yin), traditional Chinese medicine rehabilitation therapies (breathing therapy, meridian exercise method, baduanjin), and modern respiratory rehabilitation (breathing exercises, aerobic exercise, and resistance training), while the control group was treated with tea placebo combined with modern respiratory rehabilitation. The course of treatment was 14 days. Before and after treatment, patients in both groups completed a 6-min walking test, respiratory muscle strength, mMRC grade and muscle strength of extremities and trunk to assess the recovery of cardiopulmonary function and physical function. The incidence of adverse effects was observed before and after treatment. Results (1)In terms of cardiopulmonary function, when compared with those before treatment in the treatment group, the blood oxygen saturation, 6-min walking distance, and distance as a percentage of predicted value were increased(P<0. 05, P<0. 01); the 6-min distance class and Borg score were improved (P<0. 01). After treatment, compared with the control group, the blood oxygen saturation in the treatment group was increased(P <0. 05), and the 6-min distance class was improved(P <0. 05). There were no significant differences in heart rate, blood pressure, 6-min walk distance, distance as a percentage of predicted value, and Borg score between the two groups. Compared with the condition before treatment, the peak expiratory flow rate value was increased in the treatment group(P<0. 01), and the mMRC grade was improved(P<0. 01). Compared with the control group, the diaphragmatic activity was increased in the treatment group after treatment(P<0. 05). There were no significant differences in diaphragm thickness, peak expiratory flow rate and mMRC grades between the two groups. (2)In terms of physical function, after treatment, the change rates of muscle strength of anterior clamp muscle of the upper limb, trunk flexor, left hip adductor muscle in the treatment group were increased than the control group(P<0. 05, P< 0. 01). No significant adverse effects were observed in either group. Conclusion The integration of traditional and western medicine rehabilitation program is beneficial for the rehabilitation of cardiopulmonary function and physical function in patients with post-COVID-19 syndrome. [ABSTRACT FROM AUTHOR]

Introduction: Fatigue is a cumulative result of tissue damage or an energy shortage in the body. Studies have shown that one factor causing fatigue may be related to the gut microbiota. Probiotics have mainly been studied to balance intestinal flora and improve physical function, so applying probiotics to ameliorate fatigue caused by exercise could be a potential solution. Therefore, this study evaluated the efficacy of Lactobacillus johnsonii strain GKJ2 in improving exercise performance and reducing fatigue caused by exercise. Methods: The experimental design comprised an experimental and a control group. The experimental group's six-week-old male ICR mice (N = 6) were given lactic acid bacteria L. johnsonii GKJ2 powder (200 mg/kg body weight/day) for 28 consecutive days. The control group treated the same as the experimental group except no intervention of the strain GKJ2. Then, their exercise performance and the serum biochemical indicators related to fatigue were measured to evaluate the effects of L. johnsonii strain GKJ2 on ameliorating exercise fatigue. Results: The experimental group had 1.73-fold longer exhaustive swimming test times than the control mice (p < .001). In addition, the mice in the experimental group maintained significantly lower blood lactate concentrations during exercise and significantly lower blood urea nitrogen concentrations during the post-exercise rest than the control group. Moreover, the experimental group had significantly higher glycogen content in their liver (p < .001) and muscle (p < .01) tissues than the control group. Conclusion: L. johnsonii GKJ2 has the potential to improve exercise performance and reduce muscle fatigue after exercise. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To study the effect of iguratimod combined with glucosamine sulfate in the treatment of knee osteoarthritis (OA). METHODS: A total of 167 patients with OA admitted into the General Hospital of Central Theater Command of PLA from Jan. 2021 to Mar. 2022 were selected and divided into the combined group (85 cases) and control group ( 82 cases) via random number table method. The control group was treated with glucosamine sulfate, 250 mg each time and 3 times a day. The combined group was given iguratimod based on the control group, 25 mg each time and twice a day. After 8 weeks of continuous treatment, the clinical efficacy was compared between two groups, the Western Ontario and McMaster University Osteoarthritis Index ( WOMAC), visual analog score (VAS) and laboratory test results [ erythrocyte sedimentation rate ( ESR), tumor necrosis factor α ( TNF-α), interleukin 6 (IL-6) and matrix metalloproteinase 13 (MMP-13)] of the patients were statistical analysis. RESULTS: After treatment, the overall effective rate of the combined group was 92. 94% (79 / 85), which was significantly higher than that of the control group (79. 27%, 65 / 82), with statistically significant difference (P<0. 05). After treatment, the WOMAC and VAS scores of both groups were significantly reduced, the ESR, TNF-α, IL-6 and MMP-13 levels were significantly improved, and the treatment effect of the combined group was better than that of the control group, with statistically significant differences (P<0. 05). CONCLUSIONS: Iguratimod combined with glucosamine sulfate can relieve knee pain, improve joint function and mobility, reduce synovial inflammation and regulate cartilage metabolism for patients with OA. [ABSTRACT FROM AUTHOR]

BACKGROUND: With the aging of population, sarcopenia in type 2 diabetes mellitus has gradually emerged in front of people. Increasing physical activity is an important approach to prevent and treat type 2 diabetes mellitus and its related sarcopenia. However, current intervention plan, effect evaluation and mechanism of different physical activities in type 2 diabetes-related sarcopenia are still not detailed. OBJECTIVE: To analyze the intervention program, effect evaluation and mechanism of physical activity in type 2 diabetes-related sarcopenia, thereby providing theoretical basis and practical suggestions for physical activity to improve the disease. METHODS: Search terms included “Diabetes Mellitus; T2DM; Sarcopenia; Muscular Atrophy; Exercise; Training; physical activity” in English and Chinese. PubMed and CNKI were searched for relevant literature published from January 1986 to February 2022, including review papers, research papers and meta-analysis. Finally, 53 literatures were included for the review. RESULTS AND CONCLUSION: Appropriate increase in non-leisure physical activity (daily steps above 5 401 per day) can reduce the probability of sarcopenia and maintain physical exercise function in elderly type 2 diabetes patients. Increasing leisure physical activity can prevent the incidence of sarcopenia in elderly type 2 diabetes patients, and any regular physical exercise can be effective. Resistance exercise is significantly superior to aerobic exercise in the prevention and treatment of type 2 diabetes-related sarcopenia. A resistance exercise of moderate intensity and above (3 times a week, 70%-85% 1RM) can effectively increase muscle mass and strength performance in type 2 diabetes patients with sarcopenia, while aerobic exercise mainly delays skeletal muscle loss. Combining resistance exercise with aerobic exercise, nutritional intervention and health education can increase patient compliance and improve treatment efficacy. Resistance exercise mainly improves protein synthesis by activating IRS-PI3K-Akt, mTORC1, p70S6K and 4EBP1 signaling pathways, and improve muscle mass and functions by stimulating muscle satellite cell proliferation and differentiation. Aerobic exercise mainly delays muscle loss by inhibiting ubiquitin protein ligases Atrogin-1 and MuRF1 and skeletal muscle autophagy. [ABSTRACT FROM AUTHOR]

OBJECTIVE: To systematically evaluate the effects of low-load blood flow restriction training and walking training with blood flow restriction on muscle strength, muscle mass and physical performance in older adults, thereby providing a theoretical basis for the scientific application of blood flow restriction to the prevention and treatment of senile sarcopenia. METHODS: A computer-based search was conducted in PubMed, Embase, Cochrane Library, CNKI, WanFang, VIP, and CBM. Randomized controlled trials regarding the effects of blood flow restriction training on muscle mass, muscle strength and physical performance in older adults were included from inception to August, 2021. The literature quality was assessed using the bias assessment tool recommended by the Cochrane Collaboration by at least two evaluators and RevMan5.4 software was used to conduct meta-analysis of relevant data. Evaluation indicators contained three continuous variables including muscle strength, muscle mass and physical performance. Subgroup analysis was carried out for different test methods of outcome indicators included in the literature RESULTS: A total of 16 randomized controlled trials, including 348 patients in total, were included according to the inclusion criteria. The quality of the literature was graded according to the Cochrane Collaboration’s risk of bias assessment tool, including 11 studies of grade B and 5 of grade C. The results of Meta-analysis showed that compared with high-load resistance training, low-load blood flow restriction training could improve muscle strength [standardized mean difference (SMD)=-0.14, 95% confidence interval (CI):-0.34-0.06, P=0.17] and muscle mass (SMD=0.08, 95% CI: -0.23-0.40, P=0.60) in older adults; compared with low-load resistance training, low-load blood flow restriction training and walking training with blood flow restriction could significantly improve muscle strength (SMD=0.57, 95% CI: 0.28-0.87, P=0.000 2); compared with walking training, walking blood flow restriction training significantly could improve muscle strength (SMD=0.62, 95% CI: 0.32-0.91, P < 0.000 1], but there was no significant change in muscle mass (SMD=0.28, 95% CI: -0.01-0.57, P=0.06) and physical performance (SMD=0.61, 95% CI: -0.04-1.26, P=0.07). The results of subgroup analysis showed that heterogeneity was reduced. The muscle strength via low-load blood flow restriction training and walking training with blood flow restriction was significantly better than that via low-load training by means of maximum voluntary contraction (SMD=0.95, 95% CI: 0.25-1.65, P=0.008) and isokinetic torque testing (SMD=0.80, 95% CI: 0.16-1.45, P=0.01], and the physical performance via walking training with blood flow restriction was significantly better than that via walking training by means of physical function evaluation (SMD=0.94, 95% CI: 0.35-1.52, P=0.002). CONCLUSION: Meta-analysis results of the existing 16 randomized controlled trials indicate that compared with the traditional resistance training and walking training, low-load blood flow restriction training and walking training with blood flow restriction can also increase muscle strength and muscle mass in older adults. Although the large-scale randomized controlled trials are still needed on the improvement of physical performance, low-load blood flow restriction training and walking training with blood flow restriction could be good ways to prevent elder population from sarcopenia. [ABSTRACT FROM AUTHOR]

The experiment was to study the effect of Fuzi Lizhong decoction plus or minus compound Chinese medicine preparation on production performance and blood physical and chemical indexes of fertile sows. A total of 96 'Landrace× Large' binary hybrid sows with reproductive disorders were selected, and randomly divided into four groups, with four replicates in each group and six pigs in each replicate. Pigs in group A, group B and group C were fed with 3%, 2% and 1% Fuzi Lizhong decoction plus or minus compound Chinese medicine preparation in basic diet, and pigs in group D (control group) pigs were fed with 0.5% antibiotic in basic diet. The test period was 150 d. The results showed that the average litter size of group B was significantly higher than that of control group (P<0.05). The average number of live piglets in three Chinese medicine groups were significantly increased (P<0.05), the average birth weight and daily weight gain of piglets were extremely increased (P<0.01), and the average number of mummified fetuses and the diarrhea rate of piglets were significantly decreased (P<0.05). Before medication, all other blood indexes except MONO and GRAN were abnormal. After medication, the HGB and HCT of pigs in each group returned to normal values. The WBC of pigs in three traditional Chinese medicine groups returned to the normal value, while control group was still abnormal. The RBC of pigs in group A and group B returned to normal values, while those in group C and control group were abnormal. The MCHC of pigs in group A returned to normal, while the control group was still abnormal. Before medication, except serum ALB, A/G and UREA, other blood biochemical indexes of pigs in each group were in abnormal range. After medication, the blood ALT and GLU of pigs in three test groups returned to normal values, while control group remained at abnormal levels. The study indicates that the compound Chinese medicine preparation can effectively increase the number of sows born and live, reduce the number of dead and mummified fetuses, increase the average birth weight, uniformity, daily weight gain of piglets, and reduce the diarrhea rate of piglets. Combined with comprehensive analysis and evaluation of cost, the recommended addition amount was still abnormal. Before medication, except serum ALB, A/G and UREA, other blood biochemical indexes of pigs in each group were in abnormal range. After medication, the blood ALT and GLU of pigs in three test groups returned to normal values, while control group remained at abnormal levels. The study indicates that the compound Chinese medicine preparation can effectively increase the number of sows born and live, reduce the number of dead and mummified fetuses, increase the average birth weight, uniformity, daily weight gain of piglets, and reduce the diarrhea rate of piglets. Combined with comprehensive analysis and evaluation of cost, the recommended addition amount is 2%. [ABSTRACT FROM AUTHOR]

Burn scars affect not only burn patients’ physical function but also their psychosocial adjustment. Encountering stigmatizing behaviors from others may increase burn patients’ negative evaluation of their appearance—that is, body image dissatisfaction (BID), which raises their anxiety and fear of social interactions. The current study examined the association between perceived scar severity and social anxiety symptoms as mediated by perceived stigmatization and BID. Participants comprised 108 burn survivors of the 2015 Formosa Fun Coast Water Park fire disaster, including 63% females with a mean age of 24.19 years old and a mean total body surface area burned of 50.15%. We conducted a two-wave design at two years (Time 1, T1) and three years (Time 2, T2) after the 2015 fire. Serial mediation analysis was used to determine whether perceived social stigma and BID mediate the association between perceived scar severity and social anxiety symptoms serially. Results show that three years after the 2015 fire, 22.2% of the participants met the DSM-IV criteria for probable social anxiety disorder. After controlling for depressive symptoms at T1, we observed a significant serial mediation effect of T1 perceived scar severity on T2 social anxiety symptoms via T1 perceived social stigma and T1 BID. Note however that the reverse serial mediation effect was nonsignificant. In cross-lagged analysis, we determined that T1 BID was significantly predictive of T2 perceived social stigma; however, T1 perceived social stigma was not significantly predictive of T2 BID. This result contradicts the pathway of the serial mediation model described above. Overall, a relatively high proportion of burn patients reported clinically significant symptoms of social anxiety three years after the 2015 fire. Our findings highlight the importance of body image and social stigma in the postburn adjustment process. [ABSTRACT FROM AUTHOR]

To compare the effects of active exercise training and passive exercise training in patients with total knee arthroplasty (TKA). 65 patients with TKA who were treated in the Department of orthopedics of our hospital from April 2017 to August 2021 were selected. According to the random number table method, the patients were divided into active group (active exercise training) and passive group (passive exercise training), with 33 cases and 32 cases respectively. The self-care ability, balance ability, pain condition, knee function condition, knee range of motion and quality of life of the two groups were compared. Barthel index (BI), Berg Balance Scale (BBS) and American Society of Knee Surgery (KSS) scores in two groups at 1 week and 2 weeks after operation increased compared with those before operation, and visual pain simulation (VAS) scores decreased compared with that before operation (P<0.05). BI, BBS and KSS scores in active group were higher than those in passive group, and VAS score was lower than that in passive group (P<0.05). The passive range of motion (PROM) and active range of motion (AROM) in two groups decreased and then increased before operation, 3 d after operation and 7 d after operation ( P<0.05), and AROM and PROM in the active group were higher than those in the passive group ( P<0.05). 3 months after operation, the scores of physiological function, physiological function, general health, physical pain, social function, energy, mental health and emotional function in two groups were increased, and the active group was higher than the passive group (P<0.05). Compared with passive exercise training, active exercise training is more effective in patients with TKA to reduce pain, improve knee joint mobility and function, improve patients' self-care ability and improve their quality of life. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effect of trastuzumab combined with elemene injection on the expression of BNP and cTnⅠ in serum of breast cancer. Methods: 78 breast cancer patients treated in our hospital from February 2018 to June 2021 were divided into observation group (n=39) and control group (n=39) according to different treatment drugs. The observation group was treated with trastuzumab combined with elemene injection, and the control group was treated with trastuzumab injection only. The therapeutic effect, preoperative and postoperative T-lymphocyte subsets, quality of life, toxic reactions, serum BNP and cTnⅠ levels were compared between the two groups. Results: (1) The total effective rate of observation group was higher than that of control group (P<0.05). (2) The total incidence of toxicity in observation group was 15.38 %, significantly lower than 35.90 % in control group (P<0.05). (3) After treatment, CD3+ and CD4+ levels in the observation group were higher than those in the control group (P<0.05), while CD8+ levels were lower than those in the control group (P<0.05). (4) After treatment, the serum BNP and cTnⅠ levels increased gradually with the prolongation of treatment cycle, and the serum BNP and cTnⅠ levels in control group were increased compared with observation group in the same cycle (P<0.05). (5) After treatment, the scores of physical function, cognitive function and overall health status in observation group were higher than those in control group(P<0.05). Conclusion: The feasibility of trastuzumab combined with elemene injection in the treatment of breast cancer is good, which can significantly improve the treatment efficiency, improve the quality of life and immune function of patients, and reduce the serum BNP and cTnⅠ levels, which is worthy of clinical application. [ABSTRACT FROM AUTHOR]

Ginseng can be used as medicine and food, and has the function of immune regulation. The diversified deep-processed products of ginseng functional food are a hot research topic nowadays. Ginseng and Vidal ice- grapes are fermented at low temperatures. In this way, the polysaccharide-based ginsenosides of ginseng are converted into Rg2, Rf, Rg3, Rg5, CK, etc. and the bioavailability of them are significantly improved. The ginseng ice wine has a delicate and mellow entrance, and a long aftertaste, which has the functions of relieving physical fatigue, relaxing blood vessels, and enhancing immunity. The aroma components and non-volatile components of ginseng ice wine can reflect the quality and production process of the wine. In order to study the active ingredients o f ginseng ice wine, gas chromatography-triple quadrupole mass spectrometry (GC-QQQ-MS/ MS) was used to pass a DB-Heavy WAX column (30 mXO. 25 mmX O. 25 µm) with a split ratio of 1 : 20, the method of temperature programmed was used to analyze the volatile components in ginseng ice wine. Ultra performance liquid chromatography-quadrupole-orbitrap-high resolution mass spectrometry ( UPLC-Q-OrbitrapHRMS) was used to analyze the ginsenosides and polyphenols in ginseng ice wine. The polyphenols and ginsenosides in ginseng ice wine were analyzed by Sigma HPLC column Cl8 (5 cmX3. 0 mmX2. 7 µm) using acetonitrile-0. 1% formic acid aqueous solution as mobile phase with the flow rate of O. 2 mL/ min and gradient elution method. According to the quasi-molecular ion peak and fragment ion information provided by high-resolution mass spectrometry, the relative molecular mass and structure information of the compounds could be analyzed. Combining the retention time and related literature data, a total of 28 volatile components, 28 ginsenosides and 24 polyphenols were identified, which clarified the material basis of ginseng ice wine, and could be used for the identification and quality evaluation of ginseng ice wine. This research provides a theoretical basis for the further development of ginseng ice wine and a foundation for the development of ginseng functional food. [ABSTRACT FROM AUTHOR]

Supramolecular polymers, which are chain-like aggregates of monomers connected by noncovalent interactions, possess some unique chemical and physical properties and functions. In the past thirty years, great achievements have been made in the field of supramolecular polymers. So far, there are some critical issues in this research field, including the development of the driving forces and design strategies for supramolecular polymerization, and supramolecular building blocks and functions of supramolecular polymers. Recently, for the first time, Meijer et al in Eindhoven University of Technology and Yamaguchi et al in Nagoya University incorporated the frustrated Lewis pair (FLP) into the design of supramolecular polymers. By developing FLP building blocks based on planar triarylborane and triarylamine, the supramolecular polymers were constructed based on noncovalent interactions of B−N coordination, and these polymers exhibited the unique fluorescence properties with the long lifetime and circularly polarized nature. Furthermore, Yamaguchi et al disclosed a novel supramolecular polymerization method through the design of the double-trap metastable state enabled by intramolecular hydrogen bonds and intermolecular B−N coordination, achieving dynamic and controllable supramolecular polymerization. These studies thus developed new driving forces and building blocks for supramolecular polymerization, and also provided novel design strategies for supramolecular polymerization and new functions of supramolecular polymers. [ABSTRACT FROM AUTHOR]

Objective: To explore the risk factors of nutritional risk in patients with cardiac cancer, and to analyze the relationship between they and quality of life. Methods: 102 patients with cardiac cancer in our hospital from August 2017 to August 2020 were in- cluded. Nutritional risk screening 2002 (NRS2002) was used to divide the patients into nutritional risk group (n=45) and non-nutritional risk group (n=57), the risk factors of nutritional risk were analyzed. The short form of quality of life (SF-36) was used to evaluate the quality of life of patients, and the correlation between NRS2002 score and SF-36 score was analyzed. Among 102 patients, the incidence rate of nutritional risk was 44.12%. Logistic multiple regression model analysis showed that age≥ 60 years old (OR=3.914, 95% CI:1.718-8.917), the preoperative hemoglobin abnormality (OR=2.522, 95% CI:1.124-5.659), education level of primary school and below (OR=3.447, 95% CI:1.519-7.822), family monthly income≤ 1000 yuan (OR=2.974, 95% CI:1.415-6.251) were risk factor for nutritional risk in patients with cardiac cancer (P<0.05). The education level of junior college or above (OR=0.941, 95% CI: 0.897-0.987) and family monthly income>5000 yuan (OR=0.947, 95% CI: 0.901-0.995) were protective factors to prevent nutritional risk (P<0.05). The scores of emotional role function, mental health, physical function, physical pain, physical role function and overall health in nutritional risk group were lower than those in non-nutritional risk group (P<0.05). NRS2002 score was negatively correlated with emotional role function(r=-0.811), mental health (r=-0.627), physical function (r=-0.524), physical pain (r=-0.619), physical role function (r=-0.587) and overall health (r=-0.718)(P<0.05). Conclusions: The incidence rate of nutritional risk in patients with cardiac cancer is high, its occurrence is associated with variety of factors, which can reduce the quality of life. It is necessary to evaluate the nutritional risk of patients as soon as possible, and take measures to improve the quality of life. [ABSTRACT FROM AUTHOR]

Objective: To explore the influencing factors of impaired dignity in patients with colorectal cancer, and analyze its relationship with symptom groups and quality of life. Methods: A total of 110 cases of patients with colorectal cancer who were admitted to our hospital from June 2018 to April 2020 were enrolled. The impaired dignity was assessed by the Patient Dignity Inventory (PDI), and they were divided into impaired group (PDI>50 scores) and unimpaired group (PDI≤ 50 scores). Univariate and logistic regression models were used to analyze the influencing factors of patients' dignity impairment. The M.D.Anderson Symptom Inventory was used to evaluate the symptom scores of the two groups of patients, the main factors were extracted to analyze the changes in the symptom groups, and the 36-item medical outcomes study short-form (SF-36) was used to evaluate and compare the quality of life of the two groups. Results: Among 110 patients, the incidence rate of impaired dignity was 29.09%. The independence, symptom distress, social support, survival distress, peace of mind score and PDI total score of the impaired group were higher than those of the unimpaired group (P<0.05). Logistic multiple regression analysis indicated that the patient's clinical stage was stage IV (OR=2.577, 95%CI: 1.385-4.795), elementary school education and below (OR=2.996, 95%CI: 1.395-6.434), family monthly income <1000 yuan (OR=2.068, 95%CI: 1.316-3.250), tumor metastasis (OR=3.412, 95%CI: 1.498-7.772), disease course ≥ 12 months (OR=3.898, 95%CI: 1.425-10.663) were the influencing factors of impaired dignity in patients with colorectal cancer (P＜0.05). The scores of core symptoms, the degree of disturbance of symptoms to normal life and the total scores of the impaired group were higher than those of the unimpaired group, but the scores of physical function, body pain, body role function, mental health, emotional role function and general health of the impaired group were lower than those of the unimpaired group (P<0.05). Conclusion: Patients with colorectal cancer have a higher rate of impaired dignity, and which is related to many factors. The symptom groups of impaired dignity are significantly aggravated, and the quality of life is decreased. [ABSTRACT FROM AUTHOR]

BACKGROUND: MicroRNAs (miRNAs) exert crucial effects on the regulation of cell apoptosis, signal transduction, differentiation and proliferation. Literatures demonstrate that regular exercise regulates biological pathways at the genomic and post-genomic levels. OBJECTIVE: To summarize the effects of exercises on miRNAs and the correlation between miRNAs and exercise performance. METHODS: In this review, relevant studies were searched in PubMed database using “microRNAs, athletes, physical function” for relevant articles published from 2007 to 2019. Inclusion criteria included publications within recent 10 years, impact factor > 3, and sorting according to “best match.” Finally 73 articles were selected. RESULTS AND CONCLUSION: Growing evidence suggests that miRNAs are mainly regulated by human skeletal muscle movement and varies with different factors, including the type, time, frequency and intensity of exercise. MiRNAs have at least three characteristics as biomarkers, which can be obtained by noninvasive methods (found in accessible body fluids), can specifically express specific pathology and physiological state, and have stable biological characteristics. MiRNAs have been considered as potential diagnosis and prognosis biomarkers based on the physiological functions of miRNAs in different exercise states, to evaluate exercise adaptation status and prevent sports injuries. [ABSTRACT FROM AUTHOR]

Cross-domain facial expression recognition remains to be a challenging topic, due to lacking of sufficient labeled training data in practical applications. This paper exploited conditional adversarial domain adaptation to deal with the inconsistent data distributions of the cross-domain facial expressions, where it embedded an attention mechanism to extract discriminative features of facial expression images. In particular, it applied entropy function to guarantee the mobility of unpredictable facial expressions of images by priority of classification. Experimental results on both lab-controlled and real-world facial expression databases show that the effectiveness of the proposed approach for facial expression recognition. [ABSTRACT FROM AUTHOR]

Objective: To observe the clinical efficacy of Baofei Ointment in the maintenance of treatment advanced non-small cell lung cancer. Methods: 48 patients with stage III-IV Non-small cell lung cancer (NSCLC) tumors were selected as subjects in Liaoning cancer hospital & institute, the Affiliated Hospital of Liaoning Hospital of Traditional Chinese Medicine (TCM), the second affiliated hospital of Liaoning Hospital of TCM and the second Hospital of Shenyang TCM From October 2017 to October 2018. According to random number table method, the patients were divided into treatment group and control group, 24 cases in each group. Progression-free survival (PFS), quality of life before and after treatment, post-treatment TCM symptoms and Karnofsky performance status (KPS) improvement were observed and calculated. Results: After treatment, the median PFS of the treatment group was (6.00± 0.76) months, and that of the control group was (4.00± 0.81) months. Before treatment, there was no significant difference in the quality of life between the two groups (P>0.05). After treatment, the quality of life of the two groups was better than that before treatment (P<0.05). The scores of physical function, role function and emotional function in the functional area were higher than those before treatment(P<0.05). The scores of fatigue, pain, nausea and vomiting in the symptom area were lower than those before treatment (P<0.05). The scores of insomnia, constipation, anorexia and dyspnea were lower than those before treatment in the area of single symptom (P<0.05). There was no significant difference in diarrhea score and financial difficulties score (P>0.05). The general health score of patients was significantly higher than that before treatment (P<0.05). After treatment, the scores of physical function, role function and emotional function, symptoms areas, insomnia, constipation, anorexia, dyspnea and general health status in the treatment group were significantly better than those in the control group (P<0.05). After treatment, the total effective rate of TCM symptoms in the treatment group was 20 (83.33%), which was significantly higher than that in the control group 12 (50.00%)(P<0.05). After treatment, the total improvement rate of KPS score in the treatment group was 22 (91.67%), which was significantly higher than that in the control group 15 (62.50%) (P<0.05). Conclusions: Baofei Ointment can prolong the survival time, improve the quality of life, improve the symptoms of TCM and KPS score. It can be used as an alternative drug for the maintenance treatment of advanced NSCLC with tumor, and is worthy of clinical application. [ABSTRACT FROM AUTHOR]