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目的 调查缺血性卒中患者服药依从性的影响因素。 方法 前瞻性连续纳入首都医科大学附属北京天坛医院国际部2022年6月—2023年12月的缺血性卒中住院患者。采用问卷调查收集患者的一般情况、服药依从性[采用Morisky服药依从性量表（Morisky medication adherence scale，MMAS）评估]、感知健康能力[采用中文版感知健康能力量表（perceived health competence scale，PHCS）评估]、卒中复发情况等信息。根据MMAS评分将患者分为依从性差（MMAS评分＜６分）组和中高依从性（MMAS评分≥6分）组。比较两组的人口学特点、临床特点和血管危险因素情况，并采用多因素logistic回归分析服药依从性的影响因素。 结果 共纳入缺血性卒中患者212例，平均年龄（59.9±5.9）岁，MMAS评分6（6～7）分，其中服药依从性差组41例（19.34%），中高依从性组171例（80.66%）。多因素logistic回归分析显示，初中及以下学历患者依从性差的风险是大专及以上学历患者的6.290倍（95%CI 1.912～20.689，P=0.002）；无配偶患者依从性差的风险是有配偶患者的4.172倍（95%CI 1.372～12.684，P=0.012）；无业患者依从性差的风险是在职患者的4.115倍（95%CI 1.326～12.773，P=0.014）；PHCS评分低水平的患者服药依从性差的风险是中等水平患者的2.190倍（95%CI 1.098～4.370，P=0.026）。中高依从性组患者出院后1个月（99.42% vs. 92.68%，P=0.004）、3个月（98.83% vs. 80.49%，P＜0.001）和6个月（98.25% vs. 75.61%，P＜0.001）的随访完成率均高于依从性差组；3个月（3.55% vs. 12.12%，P=0.038）、6个月（4.76% vs. 16.13%，P=0.019）的卒中复发率低于依从性差组。 结论 初中及以下学历、无配偶、无业、PHCS评分低的缺血性卒中患者服药依从性差的风险较高。护理人员应综合考虑患者的个体差异，制订并实施个体化的健康教育计划，以提高患者的服药依从性。 Abstract: Objective To investigate the influencing factors of medication adherence in ischemic stroke patients. Methods This prospective study consecutively included the ischemic stroke inpatients at the international department of Beijing Tiantan Hospital, Capital Medical University from June 2022 to December 2023. A questionnaire was used to collect information on patients’ general information, medication adherence [evaluated by the Morisky medication adherence scale (MMAS)], perceived health competence [assessed by the perceived health competence scale (PHCS)], and stroke recurrence. The patients were divided into a poor adherence group (MMAS score

This paper summarized the nursing interventions based on the knowledge-attitude-practice model on anxiety and treatment compliance in an elderly patient with Ramsay-Hunt Syndrome and vestibular neuritis. This elderly female patient was diagnosed as vertigo of wind-Yang disturbance syndrome by Traditional Chinese Medicine syndrome differentiation, and she was suffered from anxiety and low treatment compliance. Based on the Traditional Chinese Medicine syndrome differentiation, nursing interventions based on the knowledge-attitude-practice model were carried out to relieve the anxiety and improve the treatment compliance. The Self-rating Anxiety Scale score dropped form 60 to 25 before discharge form hospital. The Morisky medication adherence scale score increased from 2. 5 to 8, indicating a improved level of medication adherence of the patient after intervention. (本文总结基于知信行理论(KAP)模式干预1例耳带状疱疹合并前庭神经炎老年患者焦虑情绪和治疗依从性的护理体会。本例高龄女性患者中医诊断为眩晕(风阳上扰证), 且存在焦虑情绪和治疗依从性差的问题。基于中医辨证分型, 运用KAP模式进行护理干预。患者焦虑自评量表(SAS)评分从60分(轻度焦虑)降低至25分(无焦虑), 焦虑情绪得到改善; Morisky服药依从性量表评分从2. 5分上升至8分, 治疗依从性得到提高。)

Background As the aging population continues to increase, there has been a rise in the prevalence of multimorbidity in the elderly. The adherence to medication regimens by elderly patients with multimorbidity significantly impacts the effectiveness of chronic disease management. Objective This study analyses the factors that impact medication adherence among the elderly with multimorbidity in Guangdong province. This study aims to provide a foundation for the management of multimorbidity in this population. Methods A multi-stage stratified cluster random sampling method was used to survey a population of 998 multimorbid patients aged 60 years and above in Guangdong province from October 2022 to March 2023. Medication adherence was the dependent variable, while patient sex, age, marital status, living conditions, education level, personal annual income, family encouragement for medication adherence, family doctor support, number of diseases, disease awareness, medication awareness, BMI, smoking and alcohol consumption were considered as independent variables. Multivariate Logistic regression analysis was used to identify the factors influencing medication adherence among elderly patients with multimorbidity in Guangdong province. Results A total of 1 000 questionnaires were distributed and 998 valid questionnaires were collected, with a valid recovery rate of 99.8%. Among the 998 cases of elderly patients with multimorbidity in Guangdong province, there were 719 cases (72.0%) with good adherence to medication and 279 cases (28.0%) with poor medication adherence; there were 512 cases (51.3%) of males and 486 cases (48.7%) of females. The results of multivariate Logistic regression analysis showed that: education level (high school/secondary school: OR=0.298, 95%CI=0.117-0.762; college and above: OR=0.325, 95%CI=0.127-0.831), personal annual income (>30 000 to 50 000 yuan: OR=7.694, 95%CI=2.071-28.582; >50 000 to 100 000 yuan: OR=12.408, 95%CI=3.229-47.686; >100 000 to 200 000 yuan: OR=4.893, 95%CI=1.174-20.397), and frequency of family members' supervision of medication taking (occasionally: OR=1.842, 95%CI=1.222-2.779), family doctor's help (slightly helpful: OR=2.537, 95%CI=1.531-4.205), understanding of the condition (mostly understood: OR=3.015, 95%CI=1.948-4.667; better understood: OR=3.510, 95%CI=1.955-6.300; some/no understanding: OR=3.469, 95%CI=1.338-8.994), medication concern (mostly concerned: OR=4.928, 95%CI=3.336-7.278; more concerned: OR=3.670, 95%CI=1.915-7.033; somewhat concerned/unconcerned: OR=8.560, 95%CI=2.497-29.339), BMI (too low: OR=2.303, 95%CI=1.154-4.598; overweight/obese: OR=0.598, 95%CI=0.390-0.915), and alcohol consumption (OR=1.959, 95%CI=1.270-3.022) were the influencing factors of medication adherence among elderly patients with multimorbidity in Guangdong province (P

Drug therapy is the main treatment for elderly cancer patients. Given the unique characteristics of elderly patients with cancer, including aging and underlying comorbidities, inadequate medication literacy not only decreases medication adherence but may also lead to adverse drug events. This study provides a review of the current status, influencing factors and intervention strategies related to medication literacy during oral chemotherapy in elderly cancer patients. The aim is to offer insights for enhancing medication literacy and ensuring medication safety during oral chemotherapy in elderly cancer patients. (药物治疗是老年肿瘤患者主要的治疗方式。老年肿瘤患者群体特殊, 药物素养不足不仅会降低其用药依从性, 甚至可能导致用药不良事件的发生。本研究就老年肿瘤患者口服化疗药物期间的药物素养的概念、现状、评估工具、影响因素及干预策略等方面进行综述, 旨在为提高老年肿瘤患者口服化疗药物期间的药物素养、保障用药安全提供参考。)

With the acceleration of aging population and changes of the disease spectrum, multimorbidity has become an urgent public health problem to be solved. This article searched relevant literature on medication adherence among older adults with multimorbidity both domestically and internationally, including systematically reviewing the basic information of the literature (such as publication year, research area), defining multimorbidity, measures medication adherence, analysis methodology, etc., to understand the current research status of medication adherence among older adults with multimorbidity, and to trace and analyze the hotspots of medication adherence related research among older adults with multimorbidity. [ABSTRACT FROM AUTHOR]

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Schizophrenia could affect the social and occupational functions of patients in the long term. Community-based mental health services and management models promote mental health by improving accessibility, acceptability, affordability, practicality and scalability. In the community management model, long-acting injectable antipsychotic agents are one of the main strategies for the treatment of schizophrenia, but there is a lack of relevant evidence. This paper systematically and comprehensively discussed the benefits of long-acting injectable antipsychotic agents in patients with schizophrenia, including effectiveness and safety, compliance, attitude to use, social function recovery and community rehabilitation. The results of this study showed that long-acting injectable antipsychotic agents can exert superior efficacy than oral drugs in the community rehabilitation of schizophrenia patients under different community management modes, not only reflected in the disease recurrence rate and readmission rate, but also in the recovery of social functioning and the reduction of accident rate and other aspects of excellent performance. However, the overall prescription rate of long-acting injectable antipsychotic agents is still low in China. The main reasons include insufficient information sharing between medical institutions and communities in primary level, low community medical services and treatment rate, low follow-up rate of patients, and less community psychiatric rehabilitation. This study can provide some references for the community treatment of schizophrenia patients in China, explore more community treatment programs, and improve the treatment effect and quality of life of schizophrenia patients in China.

Objective To explore the clinical value of cognitive-psychological-pain dimension special nursing in patients with advanced pancreatic cancer pain.Methods A total of 94 patients with advanced pancreatic cancer admitted to the hospital from January 2022 to April 2023 were selected and divided into the observation group and the control group by random number table method, with 47 cases in each group.The control group was given routine intervention, while the observation group received specialized nursing in the cognitive-psychological-pain dimension on the basis of the control group.The scores of the Self-rating Anxiety Scale (SAS),Self-rating Depression Scale (SDS),numerical Pain Scale (NRS),Morisky Medication Adherence Scale 8-item Chinese version (MMAS-8) and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C3) were compared between the two groups before and after intervention.Results There were no statistically significant differences in the scores of SDS and SAS between the two groups before intervention (P＞0.05) .The SDS and SAS scores of the two groups after intervention were lower than those before treatment, and the indicators of the observation group were lower than those of the control group, with statistically significant differences (P＜0.05) .There were no statistically significant difference in NRS and MMAS-8 scores between the two groups before intervention (P＞0.05) .The NRS and MMAS-8 scores of the two groups after intervention were better than those before treatment, and the indicators of the observation group were better than those of the control group, and the differences were statistically significant (P＜0.05) .There were no statistically significant differences in EORTC QLQ-C3 score between the two groups (P＞0.05) .Each item score of EORTC QLQ-C3 in the two groups were higher than those before treatment, and each indicators in the observation group were higher than those in the control group, with statistically significant differences (P＜0.05) .Conclusion The special nursing of cognitive-psychological-pain dimension for patients with advanced pancreatic cancer can not only effectively improve their anxiety, depression and pain symptoms, but also improve their medication compliance and quality of life. [ABSTRACT FROM AUTHOR]

Background Polypharmacy is increasingly common in the elderly. The medication compliance of polypharmacy is closely related to its therapeutic effect and safety. Therefore, it is of great significance to understand the medication compliance and its influencing factors in the elderly with polypharmacy at early stage. However, the conclusions of current studies vary greatly, and there is no clear and unified standard. Objective To systematically evaluate the current status of polypharmacy in the elderly and its influencing factors, in order to provide reference for improving medication compliance of polypharmacy in the elderly, reducing adverse reactions, and further developing individualized intervention programs. Methods PubMed, Embase, Web of Science, Cochrane Library, Scopus, Ovid, CBM, CNKI, Wanfang Data and VIP were searched for cohort studies, case-control studies, cross-sectional studies and other observational studies on the influencing factors of medication compliance of polypharmacy in the elderly from inception to March 2023. Two researchers independently screened the literature, evaluated the quality and extracted the data according to the inclusion and exclusion criteria. Stata 17.0 and RevMan 5.3 software were used for meta-analysis. Results A total of 19 studies were included with the total sample size of 130 047 subjects, including 50 852 subjects with good medication compliance. Meta-analysis results showed that the medication compliance rate of polypharmacy in the elderly was 41%〔95%CI (34%, 47%) 〕, which was associated with age〔OR=2.62, 95%CI (1.60, 4.78), P

Hypertension can affect the physical and mental health of older adults. This paper summarized the concept, research status, influencing factors and countermeasures of medication adherence in patients with hypertension, and provided reference for establishing nursing strategies on medication adherence in the treatment of hypertension. (高血压是老年人群中常见的心血管疾病, 严重影响老年人的身心健康和生活质量。本研究从高血压患者服药依从性的概念、国内外研究现状、影响因素及相应措施等方面进行综述, 以期为制定提高高血压患者服药依从性的相关护理措施提供参考。)

Objective To analyze the characteristics of immune cell infiltration and activation of inflammation-related signaling pathways in the intestinal mucosa and peripheral blood inflammatory microenvironment of patients with ankylosing spondylitis (AS) coexisting with Crohn’ s Disease (CD) . Methods CIBERSORT deconvolution of immune cell infiltration and gene set enrichment analysis (GSEA) were performed on microarray data from AS patients with CD obtained from the Gene Expression Omnibus (GEO) database. This analysis explored the infiltration of inflammatory immune cells and the activation status of inflammatory-related signaling pathways. Additionally, single-cell sequencing data from the intestinal mucosa and peripheral blood of AS patients with CD were used to compare the proportions of T cell subgroups and validate the activation status of inflammation-related signaling pathways. Results Using the CIBERSORT algorithm to calculate the percentage of different immune cell subtypes in the chip samples, it was found that the content of CD8+T lymphocytes in the intestinal mucosal tissue of AS patients increased gradually with the progression of the disease, from non-enteritis to subclinical enteritis, and then to enteritis. Single-cell subgroup extraction and scoring for the activation of inflammation-related pathway gene sets in lymphocytes from the intestinal mucosa and peripheral blood revealed that CD8+T lymphocytes in the intestinal mucosa of AS with CD had significantly increased activity in the TNFA-SIGNALING-VIA-NFKB, INTERFERON-GAMMA-RESPONSE, and INFLAMMATORY-RESPONSE pathways compared to AS alone, but IL17-SIGNALING-PATHWAY showed no significant activation. In peripheral blood, the pathway activities of TNFA-SIGNALING-VIA-NFKB, INTERFERON-GAMMA-RESPONSE, INFLAMMATORY-RESPONSE, and IL17-SIGNALING-PATHWAY in CD8+T lymphocytes were significantly higher in the AS with CD group compared to the AS group. Single-cell sequencing also revealed an increased proportion of CD8+T cells in the peripheral blood of AS patients with CD. Conclusion In AS patients with CD, the inflammatory signaling pathways related to TNF-α and IFN-γ are significantly activated in the intestinal mucosa. The proportion of CD8+T lymphocytes in peripheral blood is increased, serving as a potential indicator for determining the coexistence of AS and enteritis. [ABSTRACT FROM AUTHOR]

Objective To analyze the status quo of medication compliance and health empowerment of gout patients, and summarize related influencing factors, in order to provide reference for improving medication compliance. Methods We used the adherence to medication and health empowerment scale of elderly patients with chronic diseases and the health empowerment scale to investigate the adherence to medication and health empowerment of gout patients in outpatients of the Third Affiliated Hospital of Sun Yat-Sen University and the Seventh Affiliated Hospital of Sun Yat-sen University in a cross-sectional manner. Results A total of 186 patients were included, and the effective rate was 93%. The age of gout patients ranged from 25 to 76 years old, with an average age of（45.8±11.2） years old; among which 98.92% were males. In terms of medication compliance, the score of patients was 4.32±1.68, among which 81.72% had poor medication compliance. The higher the score of medication compliance, the worse the perceived health status of patients, and the two showed a negative correlation. The average total score of health empowerment was 4.06±0.43, and the health empowerment score was related to the educational level and perceived health status of patients. Conclusion In terms of medication, the compliance of gout patients is low, and the analysis of the reason has a certain relationship with the patients′ self-conscious health status. Clinical medical staff should pay attention to medication health education, emphasize reasonable and correct medication awareness and belief formation, help patients improve medication compliance, ensure the effectiveness of medication, and improve safety. [ABSTRACT FROM AUTHOR]

Poor medication adherence of patients with bipolar affective disorder is associated with stigma, drug adverse reactions and family economic burden. However, high-quality studies about n medication adherence in patients with bipolar affective disorder are relatively scarce. This paper reviewed studies on influencing factors, assessment tools and interventions of medication adherence in patients with bipolar affective disorder. Efforts should be made to investigate the intelligent tele-healthcare system and tele-healthcare-based interventions, and provide reference for establishment of a long-term accessible extended care. (双相情感障碍患者因病耻感、药物不良反应、家庭经济因素等原因, 其用药依从性水平较低。目前国内针对双相障碍服药依从性的高质量研究仍较少。本文对双相情感障碍服药依从性现状进行综述, 包括影响因素、评估工具及干预措施等。建议未来进一步探索适合我国的远程智能医疗系统、开展基于远程医疗的护理干预, 为患者提供更加便捷、远期的延续护理干预。)

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ObjectiveTo investigate the status and influencing factors of medication adherence in patients with severe mental disorders in Zhengzhou， so as to provide references for the formulation of prevention and treatment measures for severe mental disorders.MethodsFrom March to June 2021， a stratified multistage cluster sampling method was applied to select 342 patients from the National Information System for Severe Mental Disorders in Zhengzhou. The general demographic data of patients were collected via self-designed questionnaire， and the medication status was investigated， then the influential factors were summarized. The differences in influential factors of medication adherence were compared between the medication adherence group and the medication non-adherence group. Thereafter， Logistic regression analysis was applied to explore the factors influencing medication adherence.ResultsA total of 320 patients were included in the final analysis， altogether 76.56% of patients （n=245） complied with medication. The differences between patients in the medication adherence group and those in the medication non-adherence group were statistically significant in terms of residence， occupation， and outpatient chronic disease reimbursement （χ2=14.015， 7.502， 13.106， P

ObjectiveTo analyze the management and treatment for patients with severe mental disorders in Chengdu from 2016 to 2020， in order to provide references for the relevant authorities to formulate policies and improving the mental health service system.MethodsData relating to 22 districts （cities） and counties in Chengdu from January 1， 2016 to December 31， 2020 were extracted from the National Information System for Severe Mental Disorders. Indicators such as reported prevalence rate， management rate， standardized management rate， medication rate， regular medication rate and stable condition rate of patients with severe mental disorders were analyzed on a yearly basis.ResultsBy the end of 2020， there were 71 899 registered cases of severe mental disorders in Chengdu， with a reported prevalence rate of 0.34%， a standardized management rate of 95.53%， and a regular medication rate of 72.50%. From 2016 to 2020， except the reported prevalence rate （χ²=269.566， P

Background The cases of multiple chronic conditions are increasing yearly, yet their medication adherence is unsatisfactory though taking medication as prescribed is recognized as the most effective measure to manage chronic diseases. To improve the prevention and control of chronic diseases, it is crucial to identify the causes and influencing factors of non-compliance in multiple chronic conditions patients. Objective To classify the medication adherence and to identify the associated factors of each class of medication adherence in multiple chronic conditions patients. Methods This investigation was conducted between July and September 2021 with a convenience sample of 267 inpatients from two tertiary A general hospitals of Henan Province using the Chinese version of Beliefs about Medicines (BMQ-C) , the Chinese version of 8-item Morisky Medication Adherence Scale (MMAS-8-C) , and the Medication Knowledge Scale (MKS) . Latent class analysis was used to classify the medication adherence. Demographic characteristics, medication use, medication knowledge and medication beliefs were compared by the class of medication adherence. Multiple Logistic regression was used to explore the associated factors of each class of medication adherence. Results The medication adherence of the participants was divided into three latent classes, namely subjective poor medication adherence, overall poor medication adherence, and overall good medication adherence, and the prevalence of the three classes was 18.0%, 34.4% and 47.6%, respectively. The education level, occupational status after an illness, living situation, household monthly income per person, financial resources, prevalence of having pharmacist guidance, number of medications, frequency of taking medication, years of taking medication, the BMQ-C score, and MKS score in the participants differed significantly by the class of medication adherence (P

Copyright of Practical Pharmacy & Clinical Remedies is the property of Editorial Department of Practical Pharmacy & Clinical Remedies and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the Beliefs about Medicines in patients with oral Rivaroxaban for the treatment of lower extremity deep venous thrombosis, and to provide evidence for improving the quality of anticoagulation. Methods A mixed-methods study using questionnaires and cognitive interview was conducted. Totally 144 patients with deep venous thrombosis of lower extremity treated with oral Rivaroxaban anticoagulant were evaluated by a self-designed general information questionnaire and Beliefs about Medicines Questionnaire-specific (BMQ-specific), and 25 of them were interviewed by a semi-structured in-depth interview. Results The scores of necessity belief and concern belief about oral Rivaroxaban anticoagulant were (15. 14±3. 92) and (12. 60±3. 12) respectively, and the score of BMQ-specific was(2. 54±5. 09). According to the interview data, four main themes were refined as follows: Experience of anticoagulant efficacy, lack of cognition of adverse drug reactions, concern about adherence to medication, lack of continuity of medical education. Conclusion On one hand, patients accepted the need for anticoagulant medication; On the other hand, they had concerns about the potential risk of bleeding and other adverse reactions, and hope to stop the drugs as soon as possible. The medical staff should timely identify the adverse cognition of patients, strengthen medication education, and improve the quality of anticoagulant drugs. (目的 探讨下肢深静脉血栓形成患者口服利伐沙班的服药信念, 为提高抗凝质量提供依据。方法 本研究采用问卷调查与认知访谈相结合的方式, 自行设计一般资料调查表及使用特异性药物信念问卷调查表(BMQ-Specific), 对144名口服利伐沙班抗凝的下肢深静脉血栓形成患者进行问卷测评, 对其中25名患者进行半结构式深入访谈。结果 口服利伐沙班抗凝必要性维度得分为(15. 14±3. 92)分, 顾虑性维度得分(12. 60±3. 12)分, 服药信念得分(2. 54±5. 09)分。通过访谈资料构建出4个主要的主题: 抗凝疗效的体验、药物不良反应的认知不足、坚持用药的顾虑、医护宣教缺乏连续性。结论 患者认为服用抗凝药物是必要的, 但同时对抗凝药物可能发生的出血等不良反应存在疑问, 且希望能尽快停药。医护人员应及时识别患者的不良认知, 加强用药教育, 提高抗凝质量。)

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Background Acute pancreatitis is one high-incidence acute abdominal condition, which is closely related to dietary habits and lifestyle. Patients' compliance with medical advice also directly affects treatment effect and prognosis. There are some studies on compliance in patients with acute pancreatitis, but little attention has been paid to its association with recurrence. Objective To investigate the factors associated with compliance with medical advice and the association between compliance and recurrence in patients with acute pancreatitis. Methods By use of convenience sampling, four grade A tertiary hospitals in Shijiazhuang City (The First Hospital of Hebei Medical University, the Second Hospital of Hebei Medical University, the Third Hospital of Hebei Medical University, and the Fourth Hospital of Hebei Medical University) were selected as survey settings, in which patients with acute pancreatitis treated from 2019 to 2021 were selected as the subjects. Then the patients were surveyed using a self-designed questionnaire for investigating their demographics, awareness level of acute pancreatitis, and health belief during the three days prior to discharge, and were followed up by telephone at 3, 6, and 12 months after the questionnaire survey for acquiring the recurrence. They also attended another survey using a self-designed questionnaire at the last telephone follow-up for understanding their compliance. Results In all, 100 cases attended the survey, 97 of them (97.0%) who effectively responded to the survey were included for final analysis. Among the 97 respondents, 62 (63.9%) were fully compliant, 27 (27.8%) partially compliant, and 8 (8.3%) non-compliant. Multivariate Logistic regression analysis showed that gender〔OR=9.393, 95%CI (1.909, 46.223) 〕, age〔OR=1.048, 95%CI (1.000, 1.099) 〕, education level 〔OR=0.572, 95%CI (0.333, 0.985) 〕, and awareness level of acute pancreatitis〔OR=0.902, 95%CI (0.834, 0.976) 〕 were associated with compliance in patients with acute pancreatitis (P

Objective To investigate the status and influencing factors of medication adherence in patients with severe mental disorders in Zhengzhou, so as to provide references for the formulation of prevention and treatment measures for severe mental disorders. Methods From March to June 2021, a stratified multistage cluster sampling method was applied to select 342 patients from the National Information System for Severe Mental Disorders in Zhengzhou. The general demographic data of patients were collected via self-designed questionnaire, and the medication status was investigated, then the influential factors were summarized. The differences in influential factors of medication adherence were compared between the medication adherence group and the medication non-adherence group. Thereafter, Logistic regression analysis was applied to explore the factors influencing medication adherence. Results A total of 320 patients were included in the final analysis, altogether 76. 56% of patients (n=245) complied with medication. The differences between patients in the medication adherence group and those in the medication non-adherence group were statistically significant in terms of residence, occupation, and outpatient chronic disease reimbursement (χ² =14. 015, 7. 502, 13. 106, P<0. 05 or 0. 01). In the questionnaire of influential factors on medication adherence, there were statistically significant differences in the scores of lack of insight, stigma and drug-related factors between the two groups (Z=7. 588, 2. 379, 2. 893, P< 0. 05 or 0. 01). Outpatient chronic disease reimbursement was a protective factor for medication adherence (OR=2. 727, 95% CI： 1. 320~5. 634, P<0. 01), while rural residence (OR=0. 465, 95% CI：0. 221~0. 977, P<0. 05) and lack of insight (OR=0. 398, 95% CI：0. 286~0. 553,P<0. 01) were risk factors for medication adherence. Conclusion Patients with severe mental disorders in Zhengzhou have a high rate of medication adherence, moreover, the outpatient chronic disease reimbursement, lack of insight and residence may be influencing factors for medication adherence in patients with severe mental disorders. [ABSTRACT FROM AUTHOR]

Objective To analyze the management and treatment for patients with severe mental disorders in Chengdu from 2016 to 2020, in order to provide references for the relevant authorities to formulate policies and improving the mental health service system. Methods Data relating to 22 districts (cities) and counties in Chengdu from January 1, 2016 to December 31, 2020 were extracted from the National Information System for Severe Mental Disorders. Indicators such as reported prevalence rate, management rate, standardized management rate, medication rate, regular medication rate and stable condition rate of patients with severe mental disorders were analyzed on a yearly basis. Results By the end of 2020, there were 71 899 registered cases of severe mental disorders in Chengdu, with a reported prevalence rate of 0. 34%, a standardized management rate of 95. 53%, and a regular medication rate of 72. 50%. From 2016 to 2020, except the reported prevalence rate (χ²=269. 566, P<0. 01), management rate (χ²=384. 030, P<0. 01), standardized management rate (χ²=309. 742, P<0. 01), medication rate (χ²=414. 252, P<0. 01), regular medication rate (χ²=316. 172, P<0. 01) and stable condition rate (χ²=288. 335, P<0. 01) had linear trends of increasing with the annual increase. Conclusion From 2016 to 2020, the management rate, treatment rate and regular medication rate of patients with severe mental disorders have been increased year by year in Chengdu. Nevertheless, the increase in reported prevalence rate should be accompanied by strengthened management and follow-up to increase the regular medication rate to maintain the stability of patients' conditions. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the medication adherence of military academy students with superficial mycoses. Methods A 8-item Morisky medication adherence scale (MMAS) was modified into 7-item scale to evaluate the compliance of antifungal drugs in the sick students. The reliability and validity of the scale were analyzed. Results A total of 243 questionnaires were collected, of which 242 were valid questionnaires. 90.08% of the students took topical medication and 8.68% were treated both with topical and systematic combination. High, medium and low medication adherence rates as assessed by the modified MMAS were 9.09%, 23.97% and 66.94%, respectively. The reliability analysis showed that the internal consistency coefficient (Cronbach’s α ) was 0.781，and the adjusted Cronbach’s α was 0.790, indicating the high reliability of the scale. The KMO value was 0.798, and the Bartlett ’s spherical test value was 440.866, P=0.000. One factor was extracted by exploratory factor analysis. The factor loadings of the items were all above 0.5. Therefore, the high convergent validity was good. Conclusion The modified MMAS has good reliability and validity and is applicable for the evaluation of medication compliance for superficial mycoses. In this study, the military students have a low level of medication adherence for superficial mycoses. Effective measures should be taken to help students strengthen their daily medication management and improve compliance. [ABSTRACT FROM AUTHOR]

This article describes an experience providing care for non-adherence to medication in a patient with schizoaffective disorder. The patient, a long-term resident of a rehabilitation home, was experiencing auditory hallucination symptoms related to his non-adherence to medication. After being hospitalized, he refused to take oral medications, and had limited ability to effectively deal with the command auditory hallucinations, leading to his self-harm behavior. The nursing period was from April 7th to May 3rd, 2021. Data were collected using observation, in-depth interviews, and a medical history review. The nursing assessment was conducted using the five dimensions of nursing assessment. The authors used empathy, listening, and caring attitudes to establish a trusting and therapeutic interpersonal relationship with the patient. A motivational interview approach was employed to strengthen motivation to take medication, guide and link the value of personal life, and jointly draw up a patient-centered plan to establish rules to which the patient would be able to adhere. Subsequently, the patient achieved reduced interference from auditory hallucinations and close adherence to his medication protocol and attended follow-up appointments regularly in the outpatient department after discharge. [ABSTRACT FROM AUTHOR]

Objective To investigate the medication adherence and beliefs about medication in elderly patients with type 2 diabetes, and to discuss the correlation between medication adherence and medication beliefs in order to provide reference for clinical improvement of patients' medication management ability. Methods Cross-sectional study was preformed to assess the medication adherence and medication beliefs of elderly patients with type 2 diabetes in Huadong Hospital, Fudan University during Jul to Nov in 2020 by Adherence to Refills and Medications scales（ARMS) and Beliefs about Medication Questionnaire-General (BMQ-G). The standard of samples are aged type 2 diabetes patients（≥65 years old) who has had hypoglycemic drugs over 3 months.The method is according to the diagnose standard of“China Guideline for type 2 diabetes (2017 ver.) ”. Data were analyzed by t-test, Chi-square test, Spearman and binary Logistic regression. Result A total of 309 patients were included, 71.8% of patients showed with good medication adherence, 63.4% of patients showed with low medication beliefs in general overuse, 50.8% of patients showed with high medication beliefs in general harm, and 68.9% of patients showed with high medication beliefs in general benefit. Spearman correlation analysis showed that patients' medication adherence was significantly positively correlated with General-Overuse and General-Harm (General Overuse：OR=1.318, 95%CI：1.119-1.5553, P=0.001；General-Harm：OR=1.340, 95%CI：1.166-1.540, P <0.001).There was a significant negative correlation with General-Benefit（General-Benefit：OR=0.820, 95%CI：0.679-0.990, P=0.039). Logistic analysis showed that medication beliefs was an independent risk factor for medication adherence. Conclusion The general medication belief in patients with type 2 diabetes correlated with their medication adherence significantly. Clinical pharmacists should attach importance to drug education, help patients establish the correct beliefs of medication, improve their medication adherence and ensure the safety and effectiveness of medication treatment. [ABSTRACT FROM AUTHOR]

Objectives: Compared with long-term renal replacement therapy, kidney transplantation is the ideal treatment for end-stage renal disease (ESRD), significantly extending patient life and improving quality of life. Kidney transplant patients need to adhere to lifelong immunosuppressive medication regimens, but their medication adherence is generally poor compared with other organ transplant recipients. Medication adherence is closely related to medication literacy and psychological status, yet related studies are limited. This study aims to investigate the current status of medication adherence, inner strength, and medication literacy in kidney transplant patients, analyze the relationships among these 3 factors, and explore the mediating role of inner strength in the relationship between medication literacy and medication adherence., Methods: A cross-sectional survey was conducted from March to October 2023 involving 421 patients aged≥18 years who visited kidney transplantation outpatient clinics at 4 tertiary hospitals in Hunan Province. The inner strength, medication literacy, and medication adherence of kidney transplant patients were investigated using the Inner Strength Scale (ISS), the Chinese version of the Medication Literacy Assessment in Spanish and English (MedLitRxSE), and the Chinese version of the Morisky Medication Adherence Scale-8 (C-MMAS-8), respectively. Univariate analysis was performed to examine the effects of demographic and clinical data on medication adherence. Correlation analysis was conducted to explore the relationships among medication literacy, medication adherence, and inner strength. Significant variables from univariate and correlation analyses were further analyzed using multiple linear regression, and the mediating effect of inner strength was explored., Results: Among the 421 questionnaires collected, 408 were valid, with an effective rate of 96.91%. The scores of C-MMAS-8, MedLitRxSE, and ISS were 6.64±1.16, 100.63±14.67, and 8.47±4.03, respectively. Among the 408 patients, only 86 (21.08%) patients had a high level of medication adherence, whereas 230 (56.37%) patients had a medium level of medication adherence, and 92 (22.55%) patients had poor medication adherence. Univariate analysis indicated that the kidney transplant patients' age, marital status, education levels, years since their kidney transplant operation, number of hospitalizations after the kidney transplant, and adverse drug reactions showed significant differences in medication adherence (all P <0.05). Correlation analysis showed that inner strength positively correlated with both medication literacy ( r =0.183, P <0.001) and medication adherence ( r =0.201, P <0.001). Additionally, there was a positive correlation between medication adherence and medication literacy ( r =0.236, P <0.001). Inner strength accounted for 13.22% of the total effect in the mediating role between medication literacy and medication adherence., Conclusions: The level of medication adherence among kidney transplant patients needs improvement, and targeted intervention measures are essential. Inner strength mediates the relationship between medication literacy and medication adherence in these patients. Healthcare professionals should focus on enhancing medication literacy and supporting patients' inner strength to improve medication adherence.

OBJECTIVE: To probe into the application effects of experiential education of complication in improving medication literacy, medication adherence and medication compliance in patients with atrial fibrillation. METHODS: Simple random sampling method was used to select 90 patients with atrial fibrillation admitted into the cardiovascular department of Medicine of the First Affiliated Hospital of University of Science and Technology of China from Jan. to May 2020 as study subjects, and all patients were randomly divided into observation group (45 cases)and control group (45 cases). The control group was given routine health education for patients with atrial fibrillation during hospitalization, while the observation group were given experiential health education of complication based on the control group. Scores of medication literacy scale and Morisky medication adherence scale, and medication compliance rates at 1, 3 and 6 months after discharge were assessed and compared between two groups before and after the intervention. RESULTS: There were no statistical significance in differences in scores of medication literacy scale and Morisky medication adherence scale between two groups before intervention (P > 0. 05); after intervention (at discharge), the scores of medication literacy scale and Morisky medication adherence scale of the observation group were significantly better than those of the control group, and the medication adherence rates at 1, 3 and 6 months after discharge were significantly higher than those of the control group, with statistically significant differences (P < 0. 05). CONCLUSIONS: Compared with conventional health education, the experiential health education of complications can effectively improve the medication literacy and medication adherence of patients with atrial fibrillation, regulate patients’ poor medicine-taking behavior, and improve their medication compliance rate. [ABSTRACT FROM AUTHOR]

Objective To explore the status quo, correlation and influencing factors of social support and medication adherence in patients with psoriasis. Methods Convenient sampling method was used to select 206 inpatients admitted to dermatology & STD of a general hospital in Chengdu from May 2021 to June 2021. General information questionnaire, Social Support Rating Scale and Morisky Medication Adherence Scale were used for questionnaire survey. Results The median score of social support and medication adherence was 25.00 and 1.75 respectively. There were significant differences in the level of social support among patients of different ages.marital emotional status, income level, place of residence, payment, type of psoriasis, location of skin lesions, bleeding of skin lesions.pruritus of skin lesions and family history (P < 0.05). There was significant difference in medication adherence between first onset patients and recurrent patients (P < 0.05). The results of logistic regression equation showed that the possibility of low level of social support in patients with family history was 5.384 times higher than that in patients without family history (P = 0.002), The possibility of poor medication adherence in recurrent patients was 14.417 times higher than that in first-episode patients (P < 0.01). There was a positive correlation between social support and medication adherence. Conclusions Patients with psoriasis have moderate level of social support, but poor medication adherence. Clinical medical staff should focus on the elderly patients with low income, family history and recurrent disease in rural areas, so as to help improve their social support level and medication adherence. [ABSTRACT FROM AUTHOR]

Objective To assess medication adherence in elderly patients with type 2 diabetes using the Adherence to Refills and Medications Scale（ARMS），and establish the risk forecast model of selfefficacy of inappropriate medication use based on medication adherence. Methods Patients who were hospitalized in Department of Endocrinology，Huadong Hospital, Fudan university from Jul. 2018 to Jan. 2019 were investigated by Morisky Medication Adherence Scale (MMAS-8), ARMS, and the Self- Efficacy for Appropriate Medication Use Scale（SEAMS）within 24 hours after their admission. Results Of the 505 patients enrolled，161（31.9%）were with adequate and 344（68.1%）were with inadequate selfefficacy for appropriate medication use. Two groups showed significant difference in MMAS-8，ARMS, duration of diabetes and gender（P<0.05); Spearman’s rho indicated that ARMS positively correlated and MMAS-8 negatively correlated significantly with SEAMS. Binary Logistic analysis indicated that medication adherence was the risk factor of inadequate self-efficacy for appropriate medication use（ARMS： r=0.249，OR=1.282; MMAS-8: r=-1.417, OR=0.242. ROC curve showed that the area under the curve of ARMS (AUC=0.851，P<0.001，95%CI: 0.818-0.885) was greater than MMAS-8 (AUC=0.155; P< 0.001; 95%CI: 0.121-0.189), and scores of ≥16 in ARMS can be used as a predictor for inadequate selfefficacy for appropriate medication use with a sensitivity of 80.5% and specificity of 77.6%. The risk forecast model showed good sensitivity （96.3%），specificity （73.9%） and accuracy （86.0%） in the verification group. The result of kappa statistics showed that high agreement was achieved between the verification group and risk forecast model. Conclusion Compared with MMAS-8，ARMS would be more appropriate for the evaluation of medication adherence in elderly patients with T2DM. Moreover，we can use ARMS as a tool to predict the self-management ability of medicines in the elderly patients with T2DM. [ABSTRACT FROM AUTHOR]

Objective To explore factors affecting medication adherence in patients with coronary artery disease (CAD) based on Health Belief Model (HBM). Methods This community register-based,cross-sectional study consisted of individuals diagnosed with CAD in Jing'an District of Shanghai (n=189).The data were obtained through face-to-face interviews using a questionnaire covering sociodemographic characteristics,CAD status,HBM variables,Health-Promoting Lifestyle Profile Ⅱ (HPLP-Ⅱ),and the 8-item Morisky Medication Adherence Scales (MMAS-8).The independent two-sample t-test and F-test were used to analyze the influence of demographic characteristics on health-promoting lifestyle and medication adherence.Pearson's correlations were used to analyze associations among variables.Multiple linear regression models were used to evaluate effects of HBM variables on adherence to medication behavior,and health-promoting lifestyles. Results Among the 189 patients,38.6% were males and 61.4% were females, 137 cases were over 60 years old. There were significant positive correlations between the HBM variables, adherence to health promoting lifestyles and medication behavior. The value of the correlation coefficient varies from 0.173 to 0.734. Multiple linear regression analysis suggested that the perceived barriers (β=0.190,P=0.021) on health responsibility (R2=0.073,P=0.016),the perceived susceptibility (β=0.134,P=0.008) on physical activity (R2=0.274,P<0.001),the perceived severity (β=0.221,P=0.005) and the perceived benefits (β=0.100,P=0.008) on mental growth (R2=0.423,P<0.001),the perceived benefit (β=0.181,P=0.026) on stress management (R2=0.302,P<0.001),were significant impact factors,respectively.Additionally,the perceived susceptibility (β=0.689,P=0.027),perceived severity (β=0.580,P=0.003),perceived impairment (β=0.689,P=0.002),and self-efficacy (β=0.417,P=0.023) had a statistically significant effects on medication behavior (R2=0.645,P<0.001). Conclusion The HBM provides a useful framework for investigating predictors of medication adherence in patients with CAD.Future intervention to improve medication adherence should focus on changing the health beliefs among patients with CAD. [ABSTRACT FROM AUTHOR]

Objective To investigate the medication compliance in patients with chronic hepatitis B and related influencing factors. Methods A retrospective cohort study was conducted for 3732 patients with chronic hepatitis B who were treated in the outpatient service of Guangzhou Eighth People’s Hospital from January 1, 2011 to December 31, 2016, and related clinical data were collected from the hospital’s information system, including demographic features, information of the physician in charge, medication information, and examination data. According to the medication possession ratio (MPR), the patients were divided into good compliance group with 2346 patients and poor compliance group with 1386 patients. The chi-square test was used to compare demographic features, diagnosis, and treatment between the two groups, and the two-level robust Poisson regression model was used to analyze influencing factors. Results The patients with chronic hepatitis B had an MPR of 0.789±0.269, and 62.86% of the patients with good compliance had an MPR of ＞0.8. The multivariate analysis showed that method of payment, time of treatment, physician’s professional title, and pattern of medication were the influencing factors for compliance (all P＜0.05). After the control of the other covariants, the proportion of patients with good compliance among the patients covered by medical insurance was 0.119 times higher than that among the self-paying patients. The proportion of patients with good compliance tended to decrease in general, and the proportion of patients with good compliance in the 2th-5th years was 15.3%, 22.7%, 21.5%, and 34.1%, respectively, lower than that in the first year. The proportion of patients with good compliance among the patients under the charge of an associate chief physician was 0.249 times higher than that among the patients under the charge of an attending physician or a resident. The proportion of patients with good compliance among the patients receiving telbivudine was 0.120 times higher than that among the patients taking entecavir. Conclusion Medication compliance of patients with chronic hepatitis B is closely associated with medical insurance, time of treatment, professional title of the physician in charge, and pattern of medication. The patients without medical insurance should be encouraged to purchase medical insurance. It is important to strengthen health education among patients with chronic hepatitis B and promote them to follow the guidelines for the treatment of chronic hepatitis B. [ABSTRACT FROM AUTHOR]

ObjectiveTo investigate the current status of compliance with antiviral therapy with nucleos(t)ide analogues (NAs) among chronic hepatitis B (CHB) patients treated in General Hospital of Ningxia Medical University. MethodsThe CHB patients who received antiviral therapy with NAs at the outpatient and inpatient services of Department of Infectious Diseases, General Hospital of Ningxia Medical University, from May to December, 2017 were enrolled. A questionnaire survey was performed for demographics, family history of CHB, detailed doctor’s advice, daily routines, physical exercise, compliance, awareness of the knowledge about hepatitis B, health belief, and social support, and the influence of various factors on compliance with NAs treatment was analyzed. The Wilcoxon rank-sum test was used for comparison of non-normally distributed continuous data between groups, and the chi-square test or the Fisher’s exact test was used for comparison of categorical data between groups. A multivariate logistic regression analysis was used to investigate the influencing factors for compliance with antiviral therapy with NAs among CHB patients. ResultsA total of 612 questionnaires were distributed, among which 600 were collected, with a questionnaire recovery rate of 98% and a valid rate of 100%. Among the 600 CHB patients, 334 (55.67%) had good compliance with the antiviral therapy with NAs and 266 (44.33%) had poor compliance. Among the 266 CHB patients with poor compliance, 56 (21.05%) did not follow the doctor’s advice and took other drugs, 206 (77.44%) sometimes forgot medication, 187 (7030%) sometimes did not pay attention to medication (time, dose, and frequency), 135 (50.75%) reduced or stopped drugs after symptoms were improved, and 100 (37.59%) stopped the drugs due to symptom aggravation or appearance of other symptoms. The univariate analysis showed that 13 indices were the influencing factors for compliance with NAs treatment among CHB patients (all P＜0.05). A multivariate analysis was performed for these 13 indices and the results showed that race (odds ratio ［OR］=0.218, 95% confidence interval ［CI］: 0.076-0.996, P=0.007), mode of medical payment (OR=0.772, 95%CI: 0.445-0.919, P＜0.001), physical exercise (OR=2.55, 95%CI: 1.472-6.545, P=0.020), level of social support (OR=0.836, 95%CI: 0.649-0.947, P＜0.001), awareness of the outcome of incompliance (OR=0.577, 95%CI: 0.393-0.886, P＜0.001), and self-efficacy (OR=0.094, 95%CI: 0074-0.328, P＜0.001) were independent influencing factors for compliance with NAs treatment among CHB patients. ConclusionCompliance with antiviral therapy among CHB patients is closely associated with the mode of medical payment, psychological state, and self-management ability. Related measures, such as improvement of patients’ ability to pay medical expenses, education on disease risk for patients, and reduction of social discrimination, can help to improve treatment compliance. [ABSTRACT FROM AUTHOR]

Copyright of Nursing of Integrated Traditional Chinese & Western Medicine is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nursing of Integrated Traditional Chinese & Western Medicine is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nursing of Integrated Traditional Chinese & Western Medicine is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nursing of Integrated Traditional Chinese & Western Medicine is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the status of medication adherence and various types of risky behaviors of schizophrenia patients in a certain area of western China and to explore accordingly the correlation between the two., Methods: A total of 292 667 patients with schizophrenia were enrolled in a follow-up survey between 2006 and 2018. In addition, based on the outcome-wide analysis strategy, a multivariate Cox proportional risk regression model was used to estimate and compare the impact of medication adherence on different types of risky behaviors in schizophrenia patients., Results: In this 13-year prospective cohort, 65 175 patients (31.4%) showed good medication adherence, while 142 394 patients (68.6%) showed poor medication adherence. The incidence rates of various risky behaviors during the follow-up period were as follows, minor nuisances, 12.25%, violation of the Law of the People's Republic of China on Penalties for Administration of Public Security (APS law), 3.82%, violation of criminal law, 0.94%, suicide completed, 0.28%, self-harm, 1.42%, and attempted suicide, 0.82%. Schizophrenia patients who had poor medication adherence had higher risks of committing violence against others and self-inflicted injury compared to patients with good medication adherence did, with the associated effects being minor nuisances (hazard ratio [ HR ]=1.31, 95% confidence interval [ CI ]: 1.27-1.35), violation of APS law ( HR =1.47, 95% CI : 1.38-1.56), violation of criminal law ( HR =1.17, 95% CI : 1.05-1.31), and self-harm ( HR =1.43, 95% CI : 1.32-1.56), respectively, while the risk of suicide completed is lower in schizophrenia patients with poor medication adherence than that in patients with good medication adherence ( HR =0.56, 95% CI : 0.47-0.66). There was no statistically significant association between attempted suicide and medication adherence., Conclusion: There are variations in the direction and strength of the association between medication adherence and different types of risky behaviors and further research is needed to elucidate the mechanisms of the association., Competing Interests: 利益冲突　所有作者均声明不存在利益冲突, (© 2023《四川大学学报（医学版）》编辑部 版权所有Copyright ©2023 Editorial Board of Journal of Sichuan University (Medical Sciences).)

Objective： To explore the effects of medication adherence， self-management ability of patients and diabetes education on blood glucose control in diabetic patients. Methods： General demographic information， medical history， blood glucose monitoring information， medical education on diabetes mellitus were collected from 259 patients with type 2 diabetes mellitus， who sought medical care in the expert outpatient department， Chongming Branch of Shanghai Tenth People’s Hospital by using the self-designed questionnaire. Medication adherence of the diabetic patients was analyzed by Morisky medication adherence method. The obtained data was statistically analyzed by chi-square test. The relationship between general information and medication adherence， and the relationship between medication adherence or patient self-management ability and target-achieving of blood glucose standards were analyzed in the study. Results： Two hundred and fifty-nine copies of questionnaire were issued to the patients， and 230 valid questionnaires were retrieved， with an effective recovery rate of 88.8%. Of the 230 patients， 122 (53.04%) had good medication adherence and 108(46.96%) had poor adherence. The average level of glycosylated hemoglobin (HbA1c) was (9.54±2.72)%. 131 cases (56.96%) met the set blood glucose standards but 99 cases (43.04%) failed to meet. The patients without smoking or alcoholism displayed better medication adherence (P<0.05). However， smoking and alcoholism had little effect on the rate of reaching the set blood glucose standards. The rate of reaching the set blood glucose standards of patients with regular blood glucose monitoring and diabetes education was significantly higher than that of the patients without regular blood glucose monitoring and diabetes education (P<0.05). Conclusion： Medication adherence of patients was affected by many factors. Regular monitoring of blood glucose and effective obedience to health guidance could help patients to control blood glucose. [ABSTRACT FROM AUTHOR]

Copyright of Nursing of Integrated Traditional Chinese & Western Medicine is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nursing of Integrated Traditional Chinese & Western Medicine is the property of Journal of Clinical Nursing in Practice (Editorial Board, Shanghai Jiao Tong University Press) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective ：To investigate medication adherence of inhalation devices （MAID） and related influential factors in patients with asthma or chronic obstructive pulmonary disease （COPD） ．Methods ：A total of １３１ outpatients with asthma or COPD who sought medical care in the First Hospital Affiliated to Suzhou University were recruited for the study ．Questionnaire survey was performed to evaluate MAID ，medical philosophy and application scores of the inhalation devices ． The obtained data were analyzed by using t test ，Chisquare test and binary logistic regression analysis to examine the relation of the above various factors to medication adherence ．Results ：Single-factor analysis indicated that there was close association between MAID and application scores of the inhalation devices （P＜ ０ ．０１） ，medical philosophy （P＜ ０ ．０１） ，adverse drug reactions （P ＜０ ．０５） ，and the number of acute onsets （ P ＜ ０ ．０５ ） ．Binary logistic regression analysis also showed that the above indicators were closely associated with MAID （P＜ ０ ．０５ or P＜ ０ ．０１） ．Conclusion ：MAID in asthma and COPD patients was not satisfactory ．Medical personnel could take intervention measures in accordance with the influential factors of MAID ，so as to improve treatment efficacy of asthma or COPD ． [ABSTRACT FROM AUTHOR]

Evidence-based nursing science has identified psychological recovery, partnership, and medication adherence as factors that have influenced the development of mental health care. This article discusses the process by which mental health care has developed from a medical / rehabilitation-focused model to a model that focuses on patient empowerment. The current model aims to assist patients to achieve self-awareness and to develop coping skills that enhance their motivation to transform. Medical advances have improved the control of psychiatric symptoms. Following the introduction of 2nd generation antipsychotics, patients were invited to establish decisions related to these prescription medications. Under the principles of patient-centered service, Taiwanese mental health professionals have changed their relationship with patients from a therapeutic model to a mutual-partnership model. Furthermore, investigations of the therapeutic care of patients with mental illness have used the needs of patients as their starting point and emphasized various aspects of patient and caregiver needs. Taiwanese mental health professionals are searching for a model of mental health care that is superior to the traditional operative framework of medical authority. [ABSTRACT FROM AUTHOR]

Objective To evaluate the long-term effect of sustaining osteoporosis health management based on the digital platform on adherence of life style and drugs． Methods A total of 274 osteoporosis patients，collected in the orthopedic center outpatient of the 309 Hospital of PLA from August 2013 to March 2014，were randomly assigned to research group ( n = 137) and control group ( n = 137) ． The patients in research group were intervened by sustaining osteoporosis health management based on the digital platform，while the patients in control group were followed-up in the outpatient． The follow-up period lasted for 2 years． The adherence of good life style ( drinking milk，sufficient outdoor sunshine，adequate exercise，no smoking，and no alcohol intake) and medication ( calcium，vitamin D，and bisphosphonates) were evaluated in different period． Ｒesults Compared with admission， the number of patients who had good behaviors in research group and control group at one year of follow-up increased significantly ( P ＜ 0. 05) ． And the patients in research group with good behaviors increased more than those in control group ( P ＜ 0. 01) ． At two year of follow-up，the number of patients with good behaviors in control group decreased significantly ( P ＜ 0. 05) ，but those in research group had no significant change ( P ＞ 0. 05) ． And the patients with good behaviors in research group were significantly more than those in control group ( P ＜ 0. 01) ． The number of patients who had good medicine adherence of calcium，vitamin D，and bisphosphonates in short term ( 0-6 months) was not significantly different between research group and control group ( P ＞ 0. 05) ． In 6 － 12 months and in 12 － 24 months，the number of patients in both two groups with good adherence of the three drugs had gradually decreasing trend ( P ＜ 0. 05) ． However，the patients with good medicine adherence in control group decreased more than those in research group ( P ＜ 0. 01) ． Conclusion The sustaining osteoporosis health management based on the digital platform improves adherence of good behaviors and drugs． [ABSTRACT FROM AUTHOR]

Objectives: Chronic kidney disease (CKD) patients with regular dialysis treatment for more than 3 months are called maintenance hemodialysis (MHD). The degree of patients' adherence with the doctor's advice to take medicine on time is called medication adherence, which is very important for the control of the disease and the improvement of the quality of life for MHD patients. Living alone, lack of communication with children and self-neglect are risk factors for medication adherence in the older adults. Inappropriate substance use behaviors are common among older adults with self-neglect. Family resilience denotes the ability of a family to retain the stability of its structure by relying on its internal and external resources when facing a difficult situation. Family resilience entails the combination of family beliefs, interaction styles, problem-solving skills, and emotional communication which reflect supportive and positive psychological adjustment effects to benefit older persons. This study aims to provide a theoretical basis for clinical intervention level to improve medication adherence of older patients on MHD through examineing the correlation among family resilience, self-neglect, and medication adherence based on the self-reports., Methods: A random sampling method was used to gather information from 632 older patients receiving MHD treatment in Hemodialysis Center of Hunan Province between July to December 2021. For this purpose, a self-designed demographic questionnaire, the Family Resilience Questionnaire (FRQ), the Scale of the Elderly Self-Neglect (SESN), and the Morisky Medication Adherence Scale-4 (MMAS-4) were used to investigate the questionnaire data of the participants. Pearson correlation was used to examine the relationship between family resilience, self-neglect, and medication adherence in older patients and gain insight into their current status. AMOS 24.0 was used for mediation modeling. Bootstrap mediation effect test was used to evaluate the mediation effect among the 3 variables., Results: The questionnaires survey showed that the scores of FRQ, SESN, and MMAS-4 were 78.60±12.49, 7.99±5.60, and 5.93±1.40, respectively; and the medication adherence rate was 18.8%. Pearson correlation analysis showed that family resilience was negatively correlated with self-neglect ( r =-0.432, P <0.001), and was positively correlated with medication adherence ( r =0.169, P <0.001). Self-neglect was negatively correlated with medication adherence ( r =-0.217, P <0.001). Mediating effect analysis showed that the total effect of family resilience on medication adherence was significant ( β =0.214, 95% CI 0.121 to 0.313, P <0.001), and the direct effect was not significant ( β =0.058, 95% CI -0.073 to 0.187, P >0.05). Self-neglect played a major mediating effect between family resilience and medication adherence ( β =0.156, 95% CI 0.088 to 0.240, P <0.001)., Conclusions: Family resilience, self-neglect, and medication adherence among older patients on MHD are significantly related, with family resilience primarily influencing medication adherence indirectly through self-neglect.

Copyright of Chinese Journal of Clinical Healthcare is the property of Chinese Journal of Clinical Healthcare and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To evaluate the role of family doctor team service to improve the medication adherence of home-living patients with tuberculosis. Methods Totally 208 home-living patients with tuberculosis were assigned to the control group and the observation group, with 104 cases in each group. All patients received a community-based program for controlling tuberculosis, and a family doctor team service was carried out in the observation group. A Self-made questionnaire based on Morisky Medication Adherence Scale was used to investigate the medication compliance of home-living patients. Results Patients in the observation group had a higher level of medication compliance than that in the control group (P <0.05). Conclusion The family doctor team service is potentially effective to improve the medication adherence of home-living patients with tuberculosis. [ABSTRACT FROM AUTHOR]