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The effects of vortex generating agglomeration device,vortex spacing and inlet velocity of dust-bearing gas flow on the agglomeration of submicron mineral dust in vortex generator were studied by simulations and experiments to explore the agglomeration laws of submicron mineral dust.The particle trajectory was changed by the vortex generating agglomeration device in numerical simulation,and the turbulent intensity and vorticity of the agglomeration zone could be increased by decreasing the vortex spacing and increasing the inlet velocity of dust-bearing gas flow,resulting in the particle trajectory become more disordered.The experimental results show that the vortex generating agglomeration device can promote agglomeration,and the agglomeration efficiency of submicron mineral dust increases with the increase of inlet velocity of dust-bearing gas flow and decreases with the increase of vortex spacing.