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Objective To investigate the impact of preoperative abdominal aortic balloon occlusion and modified uterine vascular occlusion on repeat cesarean delivery in patients with placenta previa and placenta accreta spectrum disorders. Methods A total of 97 patients with placenta previa and placenta accreta spectrum disorders who underwent repeat cesarean section at Hefei Maternal and Child Health Hospital between April 2016 and December 2022 were included in this study. Among them, the control group consisted of 48 cases who underwent abdominal aortic balloon occlusion before the operation, while the observation group comprised 49 cases who underwent modified uterine vascular occlusion during the operation. Intraoperative and postoperative complications were observed and compared between the two groups. Results The number of bilateral uterine artery embolization post-operation and the average hospitalization cost in the observation group were significantly lower compared to those in the control group (P < 0.05). However, there were no significant differences observed between the two groups regarding average intraoperative blood loss, red blood cell suspension transfusion volume, hysterectomy rate, and bladder rupture rate (P > 0.05). Conclusions Both surgical methods effectively reduce intraoperative bleeding in the treatment of repeat cesarean section in patients with placenta previa and placenta accreta spectrum disorders. However, modified uterine vascular occlusion demonstrates no complications related to vascular intervention or X-ray exposure, ensuring high maternal and child safety while significantly reducing hospitalization costs. Therefore, it is highly recommended for clinical promotion. [ABSTRACT FROM AUTHOR]

In order to study the effect of soil composition on flue-cured tobacco composition and quality in tobacco planting area, Nanping K326 tobacco was selected to measure the contents of basic components in soil and tobacco, and the correlation between contents and smoking quality was further analyzed. The results show that the contents of available nitrogen and phosphorus in soil are positively correlated with the content of nicotine in C3f flue-cured tobacco ( r> 0. 64) . The contents of total nitrogen, total sugar and reducing sugar are positively correlated with soil organic matter ( r> 0. 72). The C3F volatility is positively correlated with soil available potassium ( r > 0. 96 ) and total nitrogen and potassium ( r > 0. 65 ) . There is a positive correlation between volatility of B2f flue-cured tobacco and total nitrogen ( r> 0. 84) and sugar ( r> 0. 74) . The results indicate that soil nutrients affect the content of chemical composition in flue-cured tobacco, as well as tobacco quality and class. The volatility of flue-cured tobacco relates to the contents and their proportion of total nitrogen, potassium, nicotine and total sugar. [ABSTRACT FROM AUTHOR]

Objective: To investigate the dynamic effects of adjunct peritoneal resuscitation ( APR ) on the early intestinal injury of rats with hemorrhagic shock, and explore its possible mechanisms., Methods: According to random number table, 96 male Wistar rats were assigned randomly into control group, shock group, Ringer solution APR group and dialysate APR group. Each group was further divided into three time points, namely 1, 2, and 6 hours after resuscitation, with 8 rats for each time point. The model of hemorrhagic shock was reproduced. The rats in the shock group received shed blood plus twice amount of normal saline as conventional intravenous resuscitation ( CIR ). Besides CIR, at the beginning of resuscitation, those rats in Ringer solution APR and dialysate APR groups were given 100 mL/kg of Ringer solution or 2.5% glucose-based peritoneal dialysis solution intravenously, respectively. The rats in four groups were sacrificed at 1, 2 and 6 hours after resuscitation, respectively. Plasma activity of diamine oxidase ( DAO ) was detected by ultraviolet spectrophotometry colorimetry. Intestinal pathological changes were observed under light microscope, and the grading of the intestinal mucosal damage ( GIMD ) score was estimated. The expressions of nuclear factor-ΚB ( NF-ΚB ) and heat shock protein 70 ( HSP70 ) mRNA in the intestinal tissue were determined with reverse transcription-polymerase chain reaction ( RT-PCR ), and the wet/dry weight ratios ( W/D ) of the remaining intestinal tissue were measured., Results: Compared with the control group, plasma activity of DAO, GIMD score, expressions of NF-ΚB and HSP70 mRNA and W/D ratios of intestinal tissue at 1 hour after resuscitation were increased significantly in the shock group. Except the expression of NF-ΚB mRNA reached the peak level at 2 hours after resuscitation, all the other parameters increased with time. Compared with the shock group, plasma activity of DAO ( U/L: 8.78±0.76 vs. 13.30±1.37, 9.67±0.92 vs. 16.56±1.61, 10.53±0.84 vs. 18.31±1.72,all P<0.05 ), GIMD score ( 1.36±0.31 vs. 3.51±0.66, 2.28±0.40 vs. 4.02±0.76, 2.47±0.38 vs. 4.76±0.77, all P<0.05 ), the expressions of NF-ΚB mRNA in the intestine tissue ( gray value: 0.658±0.062 vs. 0.765±0.067, 0.945±0.077 vs. 1.158±0.096, 0.761±0.062 vs. 0.912±0.082, all P<0.05 ), and W/D ratios ( 3.91±0.26 vs. 4.34±0.33, 3.96±0.32 vs. 4.51±0.40, 4.37±0.33 vs. 4.99±0.43, all P<0.05 ) at 1, 2, 6 hours after resuscitation in the dialysate APR group were decreased significantly, but the expressions of HSP70 mRNA were increased significantly ( gray value: 0.717±0.054 vs. 0.635±0.056, 0.853±0.068 vs. 0.745±0.071, 1.258±0.111 vs. 1.108±0.105, all P<0.05 ). The activity of DAO and GMID score at 1 hour after resuscitation in the Ringer solution APR group were decreased significantly compared with the shock group, while the differences of the other parameters between the Ringer solution APR group and shock group showed no statistical significance., Conclusions: APR with 2.5% glucose-based peritoneal dialysis solution can significantly mitigate the early intestinal injury secondary to hemorrhagic shock, and the mechanism may be associated with enhancement of the expressions of HSP70 mRNA and inhibition of the expressions of NF-ΚB mRNA.