Search

Objective:To investigate the effect and mechanism of electroacupuncture on Tongli acupoint on the right hand of normal subjects that may activate brain language area by functional magnetic resonance imaging (fMRI).Methods:Twenty-four healthy volunteers were recruited and divided into treatment group and control group. The subjects of the treatment group were stimulated by the electroacupuncture on Tongli acupoint of the right hand, while the subjecs of the control group were stimulated on a fake acupoint beside Tongli with one week time interval and block design scheme. The data were analyzed by SPM8 to generate the image of active brain area. The distribution, voxel and intensity of active areas were compared between the two groups.Results:The active brain area images of both groups include vision, language and cognition areas, such as bilateral calcarine, cerebellum, fusiform, lingual, occipital, precentral gyrus, supplementary motor area, left gyrus frontalis inferior, right gyrus temporalis inferior, etc. There were some overlap of the active areas between the two groups, but the intensities of the active brain areas in the treatment group were higher than the control group. During the first electroacupuncture task, the higher intensities of the treatment group included left cingulum post, posterior central gyrus, precentral gyrus, right middle frontal gyrus, and dorsolateral superior frontal gyrus (PP

Objective: To investigate the protective effects of Ganoderma lucidum spore polysaccharide (GLSP) on liver injury caused by acetaminophen (APAP). Methods: Fifty mice were randomly divided into five groups: Blank group, model group, positive drug group, GLSP low-dose group and GLSP high-dose group, with 10 mice in each group. After each group was pre-administered according to the corresponding dose for 14 consecutive days, the liver index, serum indexes (glutamic oxalacetic transaminase (AST), glutamic-pyruvic transaminase (ALT)) and liver tissue plasma indexes (glutathione (GSH), malonaldehyde (MDA), superoxide dismutase (SOD), Caspase-3, Bax and Bcl-xl) were determined. Results: Compared with the blank group, ALT, AST, MDA and proapoptotic genes Caspase-3 and Bax were very significantly increased in the model group (P