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As a new type of environmental pollutant, microplastics have been increasingly receiving attention for their impact on human health. Current research indicates that microplastics can enter the human body through various routes and exert neurotoxic effects. This article reviews the types, sources, and exposure pathways of microplastics, with a focus on the neurotoxic effects and potential mechanisms of microplastic exposure at different life stages in humans (fetal, infant, adult, and elderly). This review provides a comprehensive understanding of the neurotoxicity of microplastic exposure and its implications for human health risk assessment and effective prevention strategies. [ABSTRACT FROM AUTHOR]

Objective: To investigate the effects of hepatotoxicity and nephrotoxicity on rats induced by Nano-SiO2 Nano-Fe3O4 and SWCNTs., Methods: 42 Wistar rats were randomly divided into the control group, low and high dose groups of three kinds of nanoparticles. The rats were killed when rats were exposed by oral gavage for 4 weeks. The ratios of liver and kidney to body weight, the pathological changes of liver and kidney, serum certain biochemically indexes were detected., Results: The ratios of liver and kidney to body weight in experimental groups were not significantly difference in comparison to the control. The ALT and AST level in serum of rats in part experiment groups were more higher than those of the control group. The results of pathological analysis indicated that there were small amounts inflammatory cell infiltration and hepatic cell adipose degeneration in the liver of rats in high-dose group, the change of kidney were not found., Conclusion: Three kinds of nanoparticles could induce hepatotoxicity of the rats in the condition of this experiment.