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The experimental satellite of BD navigation system has assembled inter-satellite link (ISL) payloads and has obtained the real ISL observation data. The paper presents the preprocessing method of ISL and the POD method and result for Ka only observation and the combination Ka observation with L-band. It's showed that:the radial orbit error is less than 0.5 m with Ka only observation; the radial orbit error is less than 0.3 m with the observation by combining the Ka ISL with L-band data which has improved the orbit accuracy remarkably in contrast to L-band only data; the accuracy of calibrating device delay is better than 0.1 m。

To investigate the effect of ultrasound-guided percutaneous injection of cinobufotalin or anhydrous ethanol in the treatment of portal vein tumor thrombus (PVTT) through a comparative analysis. MethodsA total of 56 patients with PVTT after liver cancer surgery, who were admitted to the 94th Hospital of PLA from October 2009 to December 2011, were enrolled. Among these patients, 27 underwent ultrasound-guided percutaneous injection of cinobufotalin (cinobufotalin group) and 29 underwent ultrasound-guided percutaneous injection of anhydrous ethanol (anhydrous ethanol group). The clinical outcome and survival time were compared between the two groups after treatment, and the levels of total bilirubin (TBil), alanine aminotransferase (ALT), and aspartate aminotransferase (AST) before and after treatment were compared. The t-test was used for comparison of continuous data between groups, the chi-square test was used for comparison of categorical data between groups, the rank sum test was used for comparison of ranked data, and the Kaplan-Meier method was used for survival analysis. ResultsThe response rate showed no significant difference between the cinobufotalin group and the anhydrous ethanol group (63.0% vs 58.6%, χ2=0.111, P＞0.05). After treatment, the cinobufotalin group had significantly lower levels of TBil, ALT, and AST than the anhydrous ethanol group (t=2.24, 2.40, and 2.39, all P＜0.05). The 6-month, 1-year, and 2-year survival rates showed no significant differences between the cinobufotalin group and the anhydrous ethanol group (81.5%/63.0%/29.6% vs 82.8%/586%/31.0%, χ2=0.016, 0.111, and 0.013, all P＞0.05). ConclusionUltrasound-guided percutaneous injection of cinobufagin or anhydrous ethanol has similar short- and long-term effects in the treatment of PVTT and can inhibit the growth of tumor thrombus and prolong survival time, but cinobufagin is superior to anhydrous ethanol in the aspect of protecting liver function.

ObjectiveTo evaluate the clinical value of ultrasound-guided percutaneous cinobufagin injection for the treatment of portal vein tumor thrombus (PVTT) in primary liver cancer (PLC) patients. MethodsA total of 25 PLC patients with PVTT who were admitted to our hospital from January 2009 to March 2012 were recruited in this study. These patients underwent ultrasound-guided percutaneous cinobufagin injection three times a week, and each course of treatment was 4-5 weeks. After treatment, the clinical efficacy and survival rates were determined, and the changes in levels of alpha fetoprotein (AFP) and alanine aminotransferase (ALT) were evaluated. Results Seventeen patients showed varying degrees of improvement after treatment, with an overall response rate of 68%. In addition, the levels of AFP and ALT were significantly reduced after treatment (P＜0.05). The survival rates at 3, 6, 12, and 24 months after treatment were 88%, 76%, 60%, and 32%, respectively. ConclusionUltrasound-guided percutaneous cinobufagin injection has good efficacy in the treatment of PVTT in PLC patients and shows a good clinical value.