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Small extracellular vesicles (sEVs) which are nanoscale membranous vesicles with lipid bilayers secreted by most cells, have received widespread attention from research scholars because they are important mediators of substance exchange and signaling. The basis of curing hepatitis B disease lies in fully understanding the molecular mechanism of HBV replication regulation. HBV mainly binds to membrane surface receptors for replication and transmission, but it is not the only route of infection. In addition to the receptor route, sEVs can transmit free viral HBV to uninfected hepatocytes. However, the mechanism of sEVs mediating HBV infection is not very clear to us, therefore, this paper will focuses on the relationship between sEVs secreted by hepatocytes after HBV infection and the transmission of HBV virus and the mechanism of infection, so as to provide a theoretical guidance for clinical treatment of hepatitis B virus infection. [ABSTRACT FROM AUTHOR]

Crimes of destroying forest resources threaten the security of forest resources and hinder the high-quality development of forestry as well as the process of forestry modernization. With the crimes of destroying forest resources happening during the period from 2012 to 2021 as the sample, the temporal and spatial distribution of crimes of destroying forest resources were teased out; the causes of crimes of destroying forest resources from the perspectives of the relationship between supply and demand, crime characteristics, law enforcement and crackdowns, and the construction of the rule of law were analyzed; and treatment paths such as improving laws and regulations on crimes of destroying forest resources were proposed, in order to strengthen special rectification of crimes of destroying forest resources, and build a crime prevention and control system that puts prevention first, for the reference of people in theory and practice circles. [ABSTRACT FROM AUTHOR]

Tuberous sclerosis complex(TSC)is a rare genetic disease that can lead to benign dysplasia in multiple organs such as the skin, brain, eyes, oral cavity, heart, lungs, kidneys, liver, and bones. Its main symptoms include epilepsy, intellectual disabilities, skin depigmentation, and facial angiofibromas, whilst incidence is approximately 1 in 10 000 to 1 in 6000 newborns. This case presents a middle-aged woman who initially manifested with epilepsy and nodular depigmentation. Later, she developed a lower abdominal mass, elevated creatinine, and severe anemia. Based on clinical features and whole exome sequencing, the primary diagnosis was confirmed as TSC. Laboratory and imaging examinations revealed that the lower abdominal mass originated from the uterus. CT-guided biopsy pathology and surgical pathology suggested a combination of leiomyoma and abscess. With the involvement of multiple organs and various complications beyond the main diagnosis, the diagnostic and therapeutic process for this patient highlights the importance of rigorous clinical thinking and multidisciplinary collaboration in the diagnosis and treatment of rare and challenging diseases.

Predicting the subsequent subsidence in mining areas according to the law of mining subsidence is the key to assessing mining risks and adjusting mining planning. This study determined the available conditions of the logistic model for mining subsidence prediction through analysis and simulation experiments and proposed a method for the dynamic prediction of mining subsidence based on small baseline subset % SBAS) - interferometric synthetic aperture radar %InSAR) technology and the logistic model. Firstly, the time - series subsidence data of a mining area was obtained using the SBAS - InSAR technology. Then, taking the time series subsidence data as the data for fitting, the parameters of the logistic model were calculated pixel by pixel by using the trust region algorithm. Then, the pixel range in which the subsequent subsidence can be predicted was determined according to the available conditions of the logistic model. Finally, according to the Logistic model, the subsequent subsidence within the predictable range was predicted. This method was applied to a certain mining area in Erdos City, Inner Mongolia for tests, and the prediction results were verified using the InSAR monitoring results of corresponding dates. The predicted results after 36 days and 108 days of ming had the root mean square error % RMSE) of 0.010 1 m and 0. 023 6 m, respectively, and their proportion with prediction errors of less than 0. 03 m reached 98. 9% and 89. 3%, respectively. These results indicate that the method for dynamic prediction proposed in this study has high prediction accuracy. [ABSTRACT FROM AUTHOR]

The conveyor belt and driving device are the main components of the belt conveyor and are the high-risk areas for faults. Taking conveyor belt faults and driving device faults as the starting point, this paper analyzes the mechanisms of conveyor belt deviation, slipping, damage, stacking and scattering, as well as the faults of the driving device roller, idler and reducer. It focuses on the research progress of knowledge-driven and data-driven fault diagnosis methods for belt conveyors. Based on the knowledge processing technology, the knowledge-driven method realizes the unification of symbol processing and numerical processing, the unification of reasoning process and algorithm process. It mainly includes expert system and fault tree analysis. The data-driven method uses machine learning and data mining techniques to analyze and process historical data. It establishes diagnostic models, and achieves fault diagnosis purposes. It mainly includes support vector machines (SVM), comparison method, and diagnosis methods based on sound and vision. This paper analyzes the current challenges and future development trend of belt conveyor fault diagnosis methods. ① The historical fault data and real-time data should be combined to infer equipment health. The early minor faults should be predicted so as to remind the staff to carry out predictive maintenance. ② The correlation between coupling faults of belt conveyors should be revealed. The emerging technologies such as artificial intelligence should be used to study joint diagnosis methods for coupling faults. ③ The multimodal machine learning technology should be utilized to study the mechanism of multimodal information fusion and utilization of belt conveyors. Fault diagnosis methods for multimodal information fusion of belt conveyors needs to develop. ④ The fault knowledge graph and the belt conveyor domain knowledge should be combined to realize the belt conveyor equipment fault tracking and fault early warning. Through the knowledge query, knowledge reasoning and auxiliary decision-making functions, the capability of fault handling and precise mining of potential fault risks of equipment can be improved.

The daily use of pharmaceutical and personal care products (PPCPs) in the world has led to the widespread presence of these compounds in the environment. The effluent discharge from municipal wastewater treatment plants is the most important way for PPCPs migration to the environment. At present, the effluent from reclaimed water process of municipal wastewater treatment plants is widely used for greening irrigation, road cleaning and river water supplementation. Investigating the distribution of PPCPs in urban reclaimed water system is of great significance to assess the environmental risk and the safety of wastewater reuse. In this study, seven kinds of PPCPs were selected as the targets to study the removal efficiency of PPCPs by different treatment units in the reclaimed water process system of a wastewater treatment plant in Tianjin. The correlation analysis of these PPCPs was carried out, and the environmental risk in the receiving water was preliminarily evaluated. [ABSTRACT FROM AUTHOR]

Reverse osmosis concentrated water, referred to as ROC, is a typical high-salinity wastewater. Its direct discharge will have a negative impact on the ecosystem of the receiving water body, bringing certain environmental hazards. In this study, nanofiltration technology was used as the reverse osmosis concentrated water treatment method, reverse osmosis concentrated water pretreatment experiments were carried out to explore the salt content, hardness and alkalinity, suspended particulate matter, ionic pollutants, organic matter and SDI index in the reverse osmosis concentrated water. It is concluded that the SO42- concentration is about 30 mg/L, and the removal rate is about 99%. The main ions in the dialysate were Cl- and Na+. It can be crystallized into NaCl and Na2SO4 with higher purity after evaporation process. The effective removal of various pollution indexes in reverse osmosis concentrated water indicates that nanofiltration technology has greater application prospects in concentrated water pretreatment. [ABSTRACT FROM AUTHOR]

Objective: To realize pre-review of Chinese drug pieces prescriptions and improve the accuracy and efficiency of prescription review,so as to ensure the rationality of Chinese drug pieces prescriptions.Methods : The Chinese drug clinical prescription review system was developed,the pre-review rules and database of Chinese drug pieces prescriptions were established, and finally the smart pre-review of Chinese drug pieces prescriptions was realized. Results: The Chinese drug clinical prescription review system made the prescriptions review standards unified,fast and accurate. 100% pre-review of Chinese drug pieces prescriptions was realized,and the rationality and standardization of Chinese drug pieces prescriptions obviously improved. Finally,the Chinese drug pieces clinical prescription pre-review system obtained the copyright of national computer software (No.2019SR0757904 ).Conclusion: The Chinese drug clinical prescription pre-review system has realized the intelligent pre- review of Chinese drug pieces prescriptions,with good practicability. For this reason, it is worth further popularization. [ABSTRACT FROM AUTHOR]

Animal diseases have excelled had influence on farmers, consumers, domestic and animal industries. Study the economic impact of animal disease is of great importance to evaluate the extent of loss, and develop effective prevention measures. Current studies mainly involved the economic impact of animal disease on producers, consumers, animal industries, international trade, and regional economy. But studies ahout its influence on international trade and regional economy were less, and application of inferential statistics is not much. Compared with the international society, studies in China is lag behind. So future research should lay emphasis on influence of animal diseases to consumers, animal industries, nation and the world. We should also break through the present partial, static, theoraticle research method, and try to adhere to inter-temporal and general equilibrium theories in accordance with animal disease characteristics; and apply econometric models including spatial econometrics and epidemiology; and also pay attention to simulate and forecast economic impacts of animal diseases. [ABSTRACT FROM AUTHOR]

Studying the design manifestation of beading, a traditional decorative craftwork is studied in the use of modern woollen clothes. Analyzing the design features of popular woollen clothes in current market, to have a brief summary of the limitations of mix and match of materials, versatility of styles, diversification of colors, etc for this kind of clothes. Starting from this point, it introduces a new concept of combination of beading as traditional craftwork and design of woollen clothes. Integrating theory with practice, it discussed the three effects of the improvement of woollen clothes by the use of beading craftwork, summarized the reasonable assembly of three important elements of the consolidation of " point, line, surface" of beading craftwork, selection of pattern and decorative part. The woollen clothes will be conferred new vitality, which originally have the features of profession and briskness alone. [ABSTRACT FROM AUTHOR]

Quantum-inspired evolutionary algorithm has premature and slow convergence shortcomings on solving numerical optimization problems. To overcome these shortcomings, a novel quantum-inspired evolutionary algorithm based on culture & knowledge is proposed by introducing the cultural algorithm. This algorithm contains two evolutionary layers: quantum evolutionary layer and knowledge evolutionary layer. Since the introduction of cultural algorithm, this algorithm can achieve fine balance between exploration and exploitation as well as can escape from local optimum. Because of the new framework and quantum observation, the proposed algorithm not only retains the advantages of quantum coding, but also effectively solves numerical optimization problems. The experimental results show that the algorithm has better performance than the quantum-inspired evolutionary algorithms. The proposed algorithm performs better than other related algorithms in terms of speed and accuracy. [ABSTRACT FROM AUTHOR]

Because of the negative externality and publicity of animal epidemic diseases, it is necessary to adopt prevention and control measures. Assessment of these prevention and control strategies is helpful for understanding the cost effectiveness and providing reference to improve these strategies. Currently review articles in this area are only few, and their width and depth are insufficient. This paper summarized systematically the present status and trends of current studies, and found that those studies included 3 parts such as assessment of overall animal disease prevention and control strategies, assessment of specific animal disease prevention and control strategies, the effect contrast among different animal disease prevention and control strategies and optimization of prevention and control strategies, which mainly took cost benefit analysis as theoretical framework. However, there were few researches on follow-up assessment of the latest strategies and selective criteria for optimization scheme. Besides, the research method, analytical insight and theoretical framework could still be innovated. According to the requirements for precise assessment on animal disease prevention and control strategy, the future research should lay emphasis on evaluation of stochastic dynamic epidemic prevention strategy and dynamic optimization. Economic model of epidemiology, which combined epidemiology and economics, would be the mainstream of future study method. Due to the evaluation strategy was involved in institusion prospect, try to establish institutional economics theory framework might be able to meet the needs of present studies. [ABSTRACT FROM AUTHOR]

Based on the data of Ningxia Hui Autonomous Region forest resources inventory, field investigation and laboratory analysis, this paper studied the carbon sequestration status of forest eco-systems in Ningxia region, estimated the carbon density and storage of forest ecosystems, and analyzed their spatial distribution characteristics. The results showed that the biomass of each forest vegetation component was in the order of arbor layer (46. 64 Mg·hm-2 ) > litterfall layer (7. 34 Mg·hm-2) > fine root layer (6. 67 Mg·hm-2 ) > shrub-grass layer (0. 73 Mg·hm-2 ). Spruce (115. 43 Mg·hm-2) and Pinus tabuliformis (94. 55 Mg·hm-2 ) had higher vegetation biomasses per unit area than other tree species. Over-mature forest had the highest arbor carbon density among the forests with different ages. However, the young forest had the highest arbor carbon storage (1. 90 Tg C) due to its widest planted area. Overall, the average carbon density of forest ecosystems in Ningxia region was 265. 74 Mg C·hm-2, and the carbon storage was 43. 54 Tg C. Carbon density and storage of vegetation were 27. 24 Mg C·hm-2 and 4. 46 Tg C, respectively. Carbon storage in the soil was 8. 76 times of that in the vegetation. In the southern part of Ningxia region, the forest carbon storage was higher than in the northern part, where the low C storage was mainly related to the small forest area and young forest age structure. With the improvement of forest age structure and the further implementation of forestry ecoengineering, the forest ecosystems in Ningxia region would achieve a huge carbon sequestration potential. [ABSTRACT FROM AUTHOR]

Based on the integrated design demand of hypersonic cruise missiles, a forebody/inlet benchmark configuration was designed by the constant shock intensity method. Performances of the benchmark configuration were analyzed by means of numerical simulation. The performance response surface model was established using the Design of Experiments (DOE) and CFD results. The forebody/inlet was optimized by multi-objective particle swarm optimization (MOPSO) algorithm under the performance indices of total pressure recovery coefficient and mass capture coefficient. Performances of the optimized forebody/inlet were analyzed using CFD methods. The results show that the forebody/inlet design method is right and effective, and the benchmark configuration meets the design requirements. The forebody/inlet performances can be im proved by the multi-objective optimization method. The research results provide a reference for integrated design of scramjets to be used in hypersonic cruise missiles. [ABSTRACT FROM AUTHOR]

By the method of soil core sampling, this paper studied the fine root biomass, soil water content, and soil bulk density in 0-40 cm soil layer of four main vegetation types (Picea crassifolia forest, Pinus tabulaeformis forest, deciduous shrubs, and desert grassland) in Daluo Mountain of Ningxia, and the fine root biomass in the 0-40 cm soil layer of P. crassifolia forests with the ages of 50-, 70-, and 100 a. The fine root biomass of the four vegetation types was mainly distributed in 0-20 cm soil layer, with the rank of P. tabulaeformis forest > P. crassifolia forest > deciduous shrubs > desert grassland, and the fine root biomass of P. tabulaeformis forest was significantly higher than that of the other three vegetation types. The fine root biomass of the P. crassifolia forests with different ages was 70 a > 100 a > 50 a, and there were no significant differences in the live fine root biomass ratio and dead fine root biomass ratio among the three P. crassifolia forests. The soil water content in the 0-40 cm soil layer of the four vegetation types was P. crassifolia forest > P. tabulaeformis forest > deciduous shrubs > desert grassland, while the soil bulk density followed an opposite pattern, and was significantly negatively correlated with the fine root biomass. [ABSTRACT FROM AUTHOR]

To investigate the influences of pumice chemical surface properties on catalytic ozonation, the decomposition rate of ozone in water was measured over pumice and the mechanism of ozone catalytic decomposition was discussed. The results showed that the pseudo-first order rate of ozone decomposition increased by 37.4% for pumice catalysts. When t-BuOH was added, the rate constant decreased by 45.2 % for pumice catalysts, suggesting that the decomposition of ozone followed the mechanism of hydroxyl radical (* OH). The removal of ozone increased with the increasing of surface hydroxyl groups. High initial pH presented a positive effect in the ozone alone and ozone/pumice system. The pumice surface at nearly zero charged point was favorable for the decomposition of ozone in aqueous solution. Ozone aqueous decomposition in the presence of pumice takes place mainly on the natural material surface. The presence of metal oxides in pumice might catalyse ozone decomposition into more active radicals. [ABSTRACT FROM AUTHOR]

There are 10 pieces of Khara-Khoto documents concerning shuawei (…, the final procedure) of the whole process of zhaoshua (…, inspection and checking). These documents fall into two types: one stamped with the black ink seal of "…" (shuaqi, having been inspected and checked) and the red seal of jianchayushi (…, the official responsible for inspection and checking) and the other without such stamps. The former indicates the inspection work has already been completed, while the other has not. An analysis of the content of these documents reveals that a complete shuawei document consists of conclusion, comments and seals. The concluding part at least includes : the state of affairs recorded by the documents under inspection and the number of the documents; the reason for the inspection; the time of the making of the documents and the number of paper used; and the summary of the inspection work. The procedure of shuawei work reflected by the documents can be as follows: firstly, the staff member drafted the assessing comments; secondly, they signed their names and stamped their seals on the end of the document; thirdly, they stamped the long black seal of "…" ( Hexilongbeidao Suzhenglianfangsi Shuaiqi, inspection completed by Hexilongbeidao Inspection Commission) ; and at last, the head of the inspection team stamped his square red seal of "…" (Hexilongbeidao Suzhenglianfangsi Fensi, Branch of Hexilongbeidao Inspection Commission) in Phags-pa language. These findings are obviously significant for the study on the inspection system in the Yuan Dynasty. [ABSTRACT FROM AUTHOR]

The relationship between the mankind and the object is a basic problem that human beings have to confront. From the perspective of Zhuang Zi's philosophy, both the mankind and the object are under the framework of syncretism, distinct from the so-called technological model of mutual possession in the West. It is believed that such western attitudes towards technology might lead to some mischance such as corruption of morality, vacuity of life meaning and imbalance of the ecological environment. Zhang Zi' attitude towards technology not only resembles the western philosophy, especially the post-modern philosophy, but also offers a chance to bridge the communication between the East and the West. At present, reflections upon technology carry significant implications to the human beings' existence and sustainable development. [ABSTRACT FROM AUTHOR]

Mantle cell lymphoma (MCL) is a subtype of B-cell non-Hodgkin's lymphoma (NHL), accounting for 3-10% of NHL. MCL involves the gastrointestinal (GI) tract in 10-30% of patients and common sites of MCL GI tract involvement are the colorectum and stomach, but any region of the GI tract may be involved. GI tract involvement by MCL usually presents in the form of multiple lymphomatous polyposis involving several segments of the GI tract. A few cases of MCL presenting with a GI tract stricture have been reported. Here, we present a rare case of a small intestinal stricture caused by MCL and review the literature of this disease. [ABSTRACT FROM AUTHOR]

By using modified Levins niche width index and Pianka niche overlap index, this paper analyzed the ecological competition between constructive and dominant species in a typical steppe. The stem-and leaf extracts from the constructive species (Artemisia sacrorum) were utilized to study their allelopathic potential on the seed germination and plant growth of the dominant species (Stipa bungeana, Thymus mongolicus, S. grandis, and Leymus secalinus), and the ecological position of A. sacrorum in the steppe succession. In the steppe, S. bungeana had the widest niche width (0.99), followed by T. mongolicus (0. 94), A. sacrorum (0. 82), S. grandis (0. 76), and L. secalinus (0.73). The niche overlap value between A. sacrorum and S. bungeana, S. bun- geana and T. mongolicus, T. mongolicus and S. grandis, and A. sacrorum and T. mongolicus was 0. 90, 0. 95, 0. 94, and 0. 86, respectively. The allelopathic effects of A. sacrorum extracts varied with their concentration. For the seed germination, root growth, and shoot growth of the dominant species, A. sacrorum extracts showed a trend of promoting at low concentrations and inhibiting at high concentrations. The extracts of A. sacrorum had a stronger promotion effect on the root growth of S. bungeana than on that of T. mongolicus, but a stronger inhibition effect on the shoot growth of T. mongolicus than on that of S. bungeana. Methanol extracts had stronger allelopathic effects than aqueous extracts. The high niche overlap between A. sacrorum and S. bungeana, and T. mongoli- cus and S. grandis indicated that the steppe community would continue succession to S. bungeana, while A. sacrorum population was only an important transitional stage during the succession. The al- lelopathic effect of A. sacrorum played a driving role in the succession process. [ABSTRACT FROM AUTHOR]

Para - chloronitrobenzene degradation by Fenton-like with zero - valent iron and hydrogen peroxide was studied in depth for the purpose to solve the circulation of iron ions suffocated caused by the slow rate of Fe3+ returns Fe2+ in the traditional Fenton reaction. Different effects of hydrogen peroxide and iron dose, initial pH value and others factors were investigated. Para - chloronitrobenzene removal efficiency of 73% was achieved under optimal reaction conditions of pH value 5, with dosage of 200 mg/L zero - valent iron, and 3.5 mg/L of hydrogen peroxide after 20 min. The Removal efficiency of para - chloronitrobenzene by Fe0/H2O2 Fenton-like increased 20% - 30% than the traditional Fenton reaction under the same dosage of iron and hydrogen peroxide, and the same of pH value. And in 3 - 7 range of the pH value, para - chrornitrobenzene degradation effects were obvious by Fe0/H2O2 Fenton-like. The choro - (--Cl) and nitro- (--NO2) on the phenyl were transformed inorganic ions incomplete. The main intermediates were oxalic acid, glycolic acid, acetic acid, maleic acid, p - nitrophenol, p - chlorophenol, 2 - chloro - 5 - nitrophenol, 5 - chloro - 2 - nitrophenol. An degradation pathway of the para - chloronitrobenzene was also proposed. [ABSTRACT FROM AUTHOR]

The efficiency and mechanism of ozonation of dichlorvos (DDV) had been studied, and experimental result showed that ozone could effectively decompose DDV in the water, and the removal efficiency of DDV could be increased under basic condition. More than 90% of the DDV was removed within the initial 5 min. During the DDV ozonation degradation process, organic chlorine was almost completely converted into chloride. In the initial reaction stage, most of the TOC decomposition was finished during the first 5 min. The TOC removal rate increased with the increasing of ozone concentration. The analysis of GSMS showed that the main intermediate products were trimethyl phosphate, dichloroacetic acid (DCAA) and dichloro acetaldehyde. The quantitative analysis of DCAA showed that pH and reaction time had no obvious influence on the formation of DCAA. During the DDV ozonation process, there were three reaction modes: hydrolysis, direct ozone molecular oxidation and free radical reaction. The double bond of ethylene in the DDV molecule was first attacked by hydroxyl radical (⋅ OH) to form dimethyl phosphate and dichloroethylene radical, which were further oxidized to other kinds of product or mineralized to phosphoric acid, carbondioxide and chloride. [ABSTRACT FROM AUTHOR]

Field survey and position monitoring were conducted from 2000 to 2009 to study the effects of climate change on the distribution and growth of Lespedeza davurica community on Loess Plateau. As affected by air temperature, the appropriate growth region of L. davurica community on the Plateau had an obvious zonal distribution from northwest to southeast. For the distribution of L. davurica community, the suitable air temperature was 7.4 °C-10 °C, average population density was 13.9 plants·m-2, and reproductive branch was averagely 11.4 per cluster. As affected by precipitation gradient, the horizontal distribution of L. davurica community changed from a constructive or predominant species in typical grassland region into a companion species in forest steppe region, and then, the community gradually became dominant species. The L. davurica community appeared as an occasional species on the half sunny slope of gullies and valleys and the sand dunes in desert steppe region, and extended gradually from its optimal region with yearly precipitation 300-500 mm to the region with yearly precipitation 270-600 mm. Also, the L. davurica community extended from its optimal altitude 1100-1700 m to 600-1950 m. Under the background of global climate change, the eco-breadth of L. davurica community expanded gradually. [ABSTRACT FROM AUTHOR]

A method for the determination of Dechlorane 602 (Dec 602), Dechlorane 603 (Dec 603), D chlorane 604 (Dec 604) and Dechlorane Plus (DP) in wastewater by gas chromatography-negative ion chemical ionization mass spectrometry (GC - NCI/MS) has been developed. The water sample was extracted by classical liquid-liquid extraction method to collect the Dechloranes from both particle phase and water phase, cleaned up using silica gel and then analyzed by GC-NCI/MS under the optimized conditions of 150 °C source temperature, 150 °C quadrupole temperature, 280 °C initial temperature and 1 kV electron multiplier (E offset voltage. The quantitation limits of Dec 602, Dee 603, Dec 604 and DP were 0.01 -0. 1 ng · L-. The correlation coefficients were above 0.99 for the calibration curves. The validity of this method was demonstrated by determination of Dechloranes in wastewater of a municipal wastewater treatment plant in Harbin, China. The results indicate that the recovery rates of all Deehloranes in wastewater are 74% - 122% , the relative standard deviations (DBS are less than 13.2%. The concentrations of Dechloranes in influent and effluent are 3.2 ng · L-and 0.19 ng · L--1, respectively. Dechloranes are dominanted by DP in wastewater. [ABSTRACT FROM AUTHOR]

In order to study the function and the application value of iron silicate polymer, a series of experiment were conducted in different ozonation reaction systems for degradation of chloronitrobenzenes (CNBs)in aqueous solution. Static test results showed that the iron silicate polymer was activated in catalytic ozonation for degradation CNBs not only in distilled water, but also in tap water; compared with the ozone alone, in deionized water condition, catalyzed ozonation could make the removal efficiency of oCNB, mCNB and pCNB enhanced by 41% ,39% and 46% respectively; in tap water condition, catalyzed ozonation could make the removal efficiency of oCNB, mCNB and pCNB enhanced by 27% ,30% and 27% respectively. In a continuous flow process under the tap water condition, catalyzed ozonation could enhance the removal efficiency of oCNB, mCNB and pCNB by 20%, 24% and 20% respectively. As tea-butyl alcohol can inhibit the efficiency of catalyzed ozonation of CNBs, the mechanism of iron silicate polymer enhanced ozone oxidation of CNBs can be identified as that iron silicate polymer catalyzed ozone to decompose into hydroxyl radicals which further break up the molecule of CNBs. [ABSTRACT FROM AUTHOR]

The documents of the Heishui City are related to the Dunhuang Documents in the following aspects: they are highly similar to each other in terms of the writing materials, the time of formation, the time and place of discovery, etc. , thus making the studies on them two neighboring disciplines; they were discovered in the same international cultural context and dispersed in the same manner right after their discoveries. At the same time, there are some differences between them: the objects for study belong to different fields, each constituting the object for an independent discipline; the differences in the version form and the binding form of the representative documents are distinct, reflecting the different characteristics of the times. The Dunhuang studies, however, can set a good example for the studies on the documents of the Heishui City in terms of both academic achievements and discipline construction; their mature methodological experience means a lot for the improvement of the overall Heishui-city studies. [ABSTRACT FROM AUTHOR]

Studies the optimization technique in extracting the quinatic acid and akeboside Stc in Mutong from Akebia. Ultrasonic extraction was applied. The variety of solvent, extraction time and reagent proportion were selected as the factors and were numbered in three levels respectively. L9 (34) orthogonal test was adopted. Using the quinatic acid and akeboside Stc as indicator, measuring the content with reversed phase high-performance liquid chromatography (RP-HPLC) and variance analysis as well as directly analyzing on the measurement were carried out. The optimal condition of the orthogonal test was as follows: the solid dissolved in 80% ethanol, ultrasonic extraction lasted for 1.5 hours, and 12.5 times of solvent was needed. The result of methodological investigation for the optimum technique passed the muster. The technique proved to be practical, which laid theoretical foundation for measuring the quinatic acid and akeboside Stc in different kinds of Mutong from Akebia. [ABSTRACT FROM AUTHOR]

The catalyst of AlCl3 immobilized on 7-Al2O3 with different pores was prepared and tested in the benzylation reaction of benzene with benzyl chloride to form diphenylmethane. Conventional homogeneous pure AlCl3 was also included for comparison especially on temperature. The experimental data of forming diphenylmethane for different reaction temperature and catalyst were gained by gas chromatography. The kinetics model of the reaction, in which internal diffusion factors were considered, was established. Then the parameters of diphenylmethane apparent formation rate constant, apparent activation energy and diffusion coefficient were obtained in a liquid-solid reaction system. The results indicate that the immobilized AlCl3 catalyst was found to be more selective but less active compared to pure AlCl3 due to its pore diffusion resistance. With the decrease of the pore diameter of the supports, the diffusion coefficient of the reaction decreases sharply. The internal diffusion resistance plays an important role in the activity of benzylation reaction of benzene with benzyl chloride to form diphenylmethane over the immobilized AlCl3 catalysts. [ABSTRACT FROM AUTHOR]

R&D achievements of a field-running all optical network were summarized. Optimized design scheme of optical add-drop multiplexing (OADM) and optical cross connect (OXC) were also presented. Network control & management (NC&M) issues including the design and implementation were studied. Various network performance metrics were evaluated. The performance test results as well as the fact of good running of the multi-media services show that all-optical network becomes one kind of ideal transport technologies for metropolitan backbone networks. [ABSTRACT FROM AUTHOR]

The inter- axle differentials as a core component of power transfer cases is used to achieve the distribution of chassis power and meet the needs of working conditions of vehicle cornering and climbing,which has played a key role in ensuring the reliability of the vehicle power transmission. By using the two- stage optimization method,the inter- axle differential planetary wheel structure optimized design is carried out,on the one hand to ensure the strength of the structure,on the other hand to reduce the quality of products to meet the requirements of the vehicle light weight and high maneuverability. By the checking of classic strength calculation and finite element method,it shows that the optimization program could meet the requirements of both high torque and high- reliability design of the planetary gear inter- axle differential of multi- axis ultra- heavy-duty chassis large power transfer case.

Establishing the dynamics model of robot and its parameters is significant for simulation analysis, control algorithm verification, and implementation of human–machine interaction. Especially under various working conditions, the errors of the calculated predicted torque of each axis have the most direct negative effect. The general robot dynamics model rarely takes the minor and complex characteristics into consideration, such as the reducer flexibility, inertia force of motor rotors, and friction. However, as the structure of collaborative robots is lighter and smaller than the ordinary industrial robots, the characteristics neglected by general dynamics models account for a relatively large amount. The above facts result in a large error in the calculation and prediction of collaborative robots analysis. To address the short comings of general robot dynamics model, a network based on long short-term memory (LSTM) in deep recurrent neural network was proposed. The network compensates the general dynamics model of a self-developed six-degree-of-freedom collaborative robot based on the consideration of gravity, Coriolis force, inertial force, and friction force. In the experiment, the nondisassembly experimental measurement combined with least-squares method was used to identify the parameters. The motor current was used to evaluate the joint torque instead of mounting an expensive and inconvenient torque sensor. The excitation trajectory based on the Fourier series was optimized. The raw experimental data were used to train the proposed LSTM network. About the accuracy of the dynamic model and the compensation method for the collaborative robot, the root-mean-square error of the calculated torque relative to the actual measured torque was used to train the network and evaluate the proposed method. The analysis and the results of the experiment show that the compensated collaborative robot dynamics model based on LSTM network displays a good prediction on the actual torque, and the root-mean-square error between predicted and actual torques is reduced from 61.8% to 78.9% compared to the traditional model, the effectiveness of the proposed error compensation policy is verified.

Sympathetic remodeling after myocardial infarction is presented as denervation, sympathetic nerve sprouting and sympathetic hyperinnervation, and is closely related to ventricular tachyarrhythmias and even sudden cardiac death at convalescence in patients with myocardial infarction. This article reviews the anatomic structure, morphology and functional remodeling of cardiac sympathetic nerve, as well as its role in healed myocardial infarction identification, which may provide references for forensic research.

The carbon in Ni-based powder directly influences the property of the material. However, there is no national standard method to determine carbon content in Ni-based powder, according to the wide content range of carbon, different interferences and inconsistent optimal measuring conditions. The High Frequency Combustion-Infrared Absorption Method is already widely used to determine carbon and sulfur in new materials (such as carbon ferro-silico-manganese). Based on the preliminary study on Ni-based brazing material and Ni-based self-fluxing alloy, the high frequency combustion infrared absorption method is used to determine carbon content in Ni-Al powder. The sample is burned at high-temperature and decomposed by adding the flux of Fe and W-Sn fluxes. The measurement conditions such as flux adding amounts, sequence and sample weight have been optimized to obtain accurate results. The method has been applied to the determination of practical samples with the relative standard deviation of less than 1.2% and recovery rate of 98.0%-105.0%. The flux used by the method solves the problems of bad conductivity and splashing during burning. As new materials fall short of standard materials, the calibration curve is prepared by standard sodium carbonate relating to the carbon content, which solves the problem of no reference material and also improves the accuracy. The provided analytical method is not only suitable for the analysis of carbon in Ni-Al power within the carbon content range of 0.005%-0.60%, but also provides the basis for the development of a carbon standard analysis method for nickel-based powder.

Connecting wireless sensor networks （WSN） with Internet and providing effective services to the Internet us-ers are the heated research issues. The architecture of connecting WSN with Internet was proposed,Internet-WSN gate to realize the data-package transmission between WSN and Internet was designed. The methods of providing services were presented with the thought of network middleware. The analysis and the comparison show that the architecture presented solves the problem of connecting WSN with Internet from two levels: networks and services. This architecture has the advantages of corresponding with the network protocols available,transparent for users,simultaneously connecting sev-eral WSN with Internet,low cost and conveniently offering services.

Purpose: To exploring the clinical effect of lip muscle training combined with Frankel Ⅲ orthodontic appliances in correcting Class Ⅲ malocclusion during the mixed dentition period., Methods: One hundred children with Class Ⅲ malocclusion during the mixed dentition period admitted to Hangzhou Greentown Stomatological Hospital from June 2018 to December 2022 were selected. The children were randomly divided into a combination group (treated with lip muscle training and Frankel Ⅲ orthodontic appliance) and a control group (treated with Frankel Ⅲ orthodontic appliance), with 50 cases in each group. X-ray cephalometric indicators, temporomandibular joint parameters, upper airway measurement parameters and 12 month follow-up of the two groups of children were compared before and after treatment. SPSS 21.0 software package was used for statistical analysis., Results: Before treatment, there was no significant difference of SNA, SNB, ANB, U1-NA, L1-NB, ANS-Ptm, S-Ptm, Co Po, Co-S, MP-SN, MP-FH and NP-FH between the combination group and the control group (P＞0.05). After treatment, ANB, U1-NA, L1-NB and MP-SN in the combination group were significantly higher than those in the control group, while NP-FH were significantly lower than that in the control group(P＜0.05). Before treatment, there was no significant difference of the joint space, anterior joint space and posterior joint space between the combination group and the control group patients(P＞0.05); after treatment, the joint space and the joint space in the combination group were significantly higher than those in the control group(P＜0.05). Before treatment, there was no significant difference of Ba PNS, Ad1 PNS, Ad2 PNS, Mc1 Mc2, SPP-SPPW, U-MPW, PAS and V-LPW between the combination group and the control group(P＞0.05); after treatment, Ad2-PNS in the combination group was significantly higher than that in the control group(P＜0.05). After 12 months of follow-up, the recurrence rate of the combination group was 2.00%, which was significantly lower than that (16.00%) of the control group (P＜0.05)., Conclusions: The combination of lip muscle training and Frankel III orthodontic appliances is more conducive to correcting Class III malocclusion during the replacement period, improving upper airway morphology, and reducing the recurrence rate after treatment.

Objective: To investigate the anti- chronic myelogenous leukemia (CML) activity of Nur77-specific agonist Csn-B combined with imatinib by promoting Nur77 expression, and explore the potential role of its signaling pathway., Methods: Firstly, CCK-8 and Transwell assay were used to detect the inhibitory effects of Csn-B, imatinib, and their combination on the proliferation and migration of K562 cells. Furthermore, the apoptosis rate of K562 cells treated with Csn-B, imatinib, and their combination was detected by flow cytometry. The expression levels of Nur77, Pim-1, Drp1, p-Drp1 S616, Bcl-2 and Bax in K562 cells were detected by Western blot. Finally, the expression levels of reactive oxygen species (ROS) in K562 cells treated with Csn-B, imatinib and their combination were detected by immunofluorescence assay., Results: The level of Nur77 in CML patients decreased significantly compared with normal population in dataset of GSE43754 ( P < 0.001). Csn-B combined with imatinib could significantly inhibit the proliferation and migration of K562 cells (both P < 0.001), and induce apoptosis ( P < 0.001). Csn-B promoted Nur77 expression in K562 cells, and synergistically enhanced imatinib sensitivity when combined with imatinib. Csn-B combined with imatinib could significantly enhanced ROS levels in K562 cells and mitochondria compared with single-drug treatment (both P < 0.001)., Conclusion: Csn-B combined with imatinib can enhance ROS expression and induce apoptosis of K562 cells through Nur77/Pim-1/Drp1 pathway.

The global sharp decline of pollinators is one of the hot issues concerned by ecologists, mainly driven by global climate change, land use change, habitat fragmentation and harmful substances such as pesticides brought by industrial and agricultural production. In contrast, the potential impact of soil heavy metal pollution on pollinators is lack of in-depth evaluation. Heavy metals in soil would enter plant tissues, such as flowers, etc ., and be transmitted to pollinators during pollination. By affecting pollinators' behavior, they can change plant fitness for male and female. This review aimed to comprehensively sort out the status of research and existing problems, which would deepen our understanding on the ecological consequences caused by heavy metal pollution as well as the plant-animal relationship in response to environmental change. Summarizing previous researches, we reviewed findings on the pattern of heavy metal accumulation in flowers, the impacts of flower heavy metal accumulation on plant male and female fitnesses in addition to pollination behavior and the key aspects of life history of bees, to help understand the interrelationship between flower heavy metal accumulation and pollinators, and further expand the scientific understanding on the internal connection between soil heavy metal pollution and the decline of pollinators.

Objective: To study the effects of Synaptotagmin1 gene knockout (Syt1 +/- ) on emotional behavior in mice and explore its possible mechanisms. Methods: Five 8-week-old male Syt1 +/- mice and five wild-type (WT) mice in the same litter were selected. The expressions of Syt1 in 6 mice brain regions of prelimbic cortex (PL), hippocampus (HIP), amygdala (AMY), accumbens nucleus (ACB), caudoputamen (CP) and ventral tegmental area (VTA) were detected by Immunofluorescence staining. Nine 8-week-old male Syt1 +/- mice and ten WT mice were selected as controls. The anxiety-like behaviors of adult Syt1 +/- mice and WT mice were detected by open field test, elevated plus maze test and forced swim test. In addition, five 8-week-old male Syt1 +/- mice and five WT mice were selected to detect the glutamate content in prelimbic cortex, hippocampus and amygdala. Results: Compared with WT mice, the number of Syt1 positive cells in PL, HIP, AMY, ACB, CP and VTA were decreased significantly in Syt1 +/- mice ( P ＜0.01); Syt1 +/- mice had less total movement distance in open field test ( P ＜0.01), more preference for peripheral area ( P ＜0.01) and less desire to explore the central platform ( P ＜0.01), while Syt1 +/- mice preferred to stay in a closed and safe environment ( P ＜0.01); the number ( P ＜0.05) and the time spent in open-arm explorations ( P ＜0.01) were reduced significantly; the immobile time of Syt1 +/- mice was increased in the forced swim test ( P ＜0.01). Meanwhile, the concentration of glutamate in the amygdala of Syt1 +/- mice was increased significantly ( P ＜0.01). Conclusion: Syt1 gene knockout leads to significant anxiety-like behavior in mice, which is deduced that related to the increase of glutamate content in the amygdala.