9 results on '"Guglielmo, M."'
Search Results
2. Role of hepatocyte growth factor (HGF)/c?Met signaling pathway in early follicular development in mice.
- Author
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Li Mingxing, Li Zhuoxian, Li Kangmei, Chen Xiurong, Zhou Yanping, Huang Yulin, Bai Lin, Wu Zhansh- Uai, Xia Meng, and He Guozhen
- Subjects
HEPATOCYTE growth factor ,MET receptor ,CELLULAR signal transduction ,PI3K/AKT pathway ,GENE expression - Abstract
Objective: To investigate the role of hepatocyte growth factor and its receptor c-Met (HGF/ c-Met) signaling pathway in early follicular development in mice via detecting the expression of HGF/c-Met in early mouse ovarian tissue and then analyze the biological process of HGF/c-Met signaling pathway and its possible involvement in intracellular signaling pathways by using bioinformatics for the purpose of further studying the molecular mechanism of the signaling pathway in the early follicle development. Methods. Thirty-five female Kunming mice and 15 male ones were fed in 15 cages with the female-to-male ratio of 2,1. The ovaries of mice at 3, 7, 14 and 21 days after birth were collected. Immunohistochemical staining and Western blotting were applied to detect the expression levels of HGF and c-Met protein in the ovarian tissues. Quantitative Real-time PCR,q-PCR, was used to detect the expression levels of HGF and C-Met mRNA in the early ovarian tissues of mice. Results, HGF and c-Met proteins were expressed in the ovarian tissues of the mice at 3, 7, 14 and 21 days, presenting an increasing trend with the increase of age by day,P < 0.05,. The mRNA levels of HGF and c-Met also showed the same trend,P < 0.05,. Bioinformatics analysis revealed that the HGF/c-Met signaling pathway involved in a variety of biological processes and signaling pathways such as PI3K/AKT. Conclusions,HGF/c-Met signaling pathway is involved in early follicular development in mice. It may regulate primal follicular initiation and follicular develop, ment through intracellular signaling pathway PI3K/AKT. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. 隧道半径对地铁列车火灾烟气 蔓延特性影响研究.
- Author
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周丹, 唐子童, 胡天恩, and 陈涛
- Subjects
SUBWAY tunnels ,WIND tunnels ,TUNNEL ventilation ,RELATIVE motion ,NAVIER-Stokes equations ,TUNNELS ,MOTION - Abstract
Copyright of Journal of Railway Science & Engineering is the property of Journal of Railway Science & Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
4. 高速公路特长隧道环境车道行驶速度特性及短时预测模型研究.
- Author
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吴 玲, 刘建蓓, 单东辉, 马小龙, and 王元庆
- Abstract
Copyright of Tunnel Construction / Suidao Jianshe (Zhong-Yingwen Ban) is the property of Tunnel Construction Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
5. 冠状动脉周围脂肪组织的影像学研究进展.
- Author
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闫婷, 综述, 原杰, 唐笑先, and 审校
- Abstract
Copyright of Diagnostic Imaging & Interventional Radiology is the property of Editorial Office of Diagnostic Imaging & Interventional Radiology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2023
- Full Text
- View/download PDF
6. The Effects of Supportive Caring on Symptoms Distress, Nursing Needs, and Depression in Patients With Brain Tumor After Surgery: A Preliminary Study.
- Author
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Li-Chu WU and Yu-Hua LIN
- Subjects
PREVENTION of mental depression ,CANCER patient psychology ,EXPERIMENTAL design ,SOCIAL support ,NURSING ,SELF-report inventories ,BRAIN tumors ,RANDOMIZED controlled trials ,PRE-tests & post-tests ,SURVEYS ,SYMPTOMS ,CENTER for Epidemiologic Studies Depression Scale ,STATISTICAL sampling ,PSYCHOLOGICAL distress ,MEDICAL needs assessment - Abstract
Background: Brain tumors are mainly treated with surgery. However, patients still experience many symptoms and nursing needs due to disease and treatment-related factors that, if not improved in a timely manner, may result in depression. Purpose: The purpose of this study was to examine the effectiveness of supportive caring on symptom distress, nursing needs, and depressive symptoms in patients with brain tumor after surgery. Methods: This study adopted a two-group, pre- and post-test experimental design. The enrolled participants were randomized into two groups. Those in the experimental group received a phone-based supportive caring intervention twice at 1 and 3 months after surgery. Those in the control group received usual discharge care. The measurement outcomes included a supportive care needs survey, symptom distress scales, and the center for epidemiological studies of depression. Baseline data was collected prior to hospital discharge (T0), with follow-up data collected at one month (T1), three months (T2), and six months (T3) after surgery. Results: The results of the generalized estimating equation analysis showed that nursing needs in the experimental group at T1 (β = -23.61, p < .001), T2 (β = -22.51, p < .001), and T3 (β = -22.26, p < .001) were significant lower than in the control group. Also, symptom distress in the experimental group at T1 (β = -7.03, p = .019) and T2 (β = -8.39, p = .003) was significantly lower than in the control group. However, depressive symptoms in the experimental group were lower than in the control group only at T2 (β = -8.55, p = .005). Conclusion: The results of this study confirm that supportive care helps improve nursing needs, symptoms distress, and depressive symptoms in patients with brain tumor after surgery. Medical team members should pay attention to these issues following surgery. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
7. 红景天当归不同配伍对免疫低下小鼠 免疫功能的影响.
- Author
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史顶聪, 赵宏宇, 佟晓乐, and 张凤清
- Subjects
DELAYED hypersensitivity ,THYMUS ,HEMOLYSIS & hemolysins ,SPLEEN ,MICE ,EAR - Abstract
Copyright of Food Research & Development is the property of Food Research & Development Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2020
- Full Text
- View/download PDF
8. 微/纳多级结构TiO2涂层的制备及生物学性能.
- Author
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顾静萍, 谢有桃, 黄利平, 贺延昌, 赵君, 郑学斌, 李红, and 孙晋良
- Abstract
Copyright of Journal of Shanghai University / Shanghai Daxue Xuebao is the property of Journal of Shanghai University (Natural Sciences) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2018
- Full Text
- View/download PDF
9. 不同通气模式对老年胸科手术患者呼吸和循环的影响.
- Author
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邓立强 and 刘睿
- Abstract
Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2016
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