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In order to improve the reaction kinetic characteristics of Al powder in CL-20-based aluminum-containing explosives, CL-20/Al composite particles were prepared by solvent-non-solvent method, and CL-20 particles and Al particles were close contacted in microstructures. Then the composite explosives containing 85% CL-20/10% Al/5%-polymer binder composite particles were prepared by the direct method. The mechanical sensitivity, explosion heat, explosion tank test results and cylinder test results were compared between CL-20-based aluminum-containing explosives with the method in this work and the same formula prepared by conventional method. The results show that CL-20/Al composite particles can slightly increase the impact sensitivities of explosives, and the friction sensitivity is not changed. Through recombination of CL-20/Al on the micro-structure, because of shortening the diffusion distance between Al powder and detonation products, the reaction kinetics of Al powders can be significantly improved. Further, the reaction completeness of Al powders in the explosion process of aluminum-containing explosives can be improved, and it forces the reaction of part of Al powders occurring in the detonation zone. Compared with the conventional method, the explosion heat of explosive increases from 6 787 J/g to 6 930 J/g, the maximum temperature of explosion field in explosive tank increases from 544.3°C to 661.2 °C, and the Gurney coefficient increases from 2.88 mm/jus to 3.10 mm/µs. [ABSTRACT FROM AUTHOR]

To explore the stability of high-energy fuels under strong shock wave effect and simulate the practical enviroment, the explosion and electric detonation shock methods were used to study the stability of boron hydride salt (BHN-10) under shock effect as well as the gas and solid products produced by the decomposition of the boron hydride salt. Moreover, HMX was introduced in BHN-10 to investigate the effect on the decomposition efficiency of BHN-10. The results show that BHN-10 has good stability to the impact of detonation shock generated by single explosive. The shock wave of 1.0 GPa magnitude generated by single explosive detonation cannot promote the decomposition of BHN-10. BHN-10 has relatively low stability under the shock of electric detonation. The interaction of shock and heat generated by the plasma electric detonation method result in the decomposition of BHN-10, and the organic flammable gas products with high calorific value contain triethylamine, nitrile, paraffin, olefin or alkyne. After adding HMX into the BHN-10, the length of the carbon chain of the gas products is shortened and less than 4 carbon atoms except for triethylamine. The addition of HMX can greatly improve the decomposition efficiency of the BHN-10 fuel, and generate low carbon chain flammable gases with a higher proportion. Under the N2 atmosphere, the solid decomposition products of BHN-10 contain C60 and orthorhombic B12H16. Under the air atmosphere, the solid decomposition products are C60, B12H16, B2O3 and boric acid. After adding HMX, the solid products from the decomposition of the BHN-10 are mainly amorphous phases of C and B elements. [ABSTRACT FROM AUTHOR]

To predict JWL (Jones-Wilkins-Lee) equation of state (EOS) parameters, a KHT Code has been programmed according to the KHT (Kihara-Hikita-Tanaka) EOS of detonation production. The detonation parameters of RDX-based aluminized explosives calculated by KHT code have a good consistency with the experimental values, which proves the credibility of the KHT code. On this basis, the calculated isentropic expansion data of the detonation production using KHT code were used to predict the JWL EOS parameters for RDX-based aluminized explosives. The numerical test by employing AUTODYN software with the predicted JWL EOS parameters as input data was carried out to simulate the explosion of 1 kg RDX-based aluminized explosives under water 4.7 m. It was found that the shock wave peak pressures of numerical calculation were very similar to the experimental results. The results indicate that the proposed prediction method using KHT Code is reliable and available. [ABSTRACT FROM AUTHOR]

The detonation parameters of RDX-based aluminized explosive were measured by test, and the test result was verified by KHT code. The influence law of Al/O ratio on detonation pressure, detonation velocity and heat was analyzed. Underwater explosion experiments were carried out on shock wave propagation and bubble pulse of 1 kg cylindrical RDX-based aluminized explosive under water 4. 7 m. The coefficients of similitude equation for peak pressure and attenuation time constant were fitted. The study indicates that the detonation pressure and velocity reduce linearly with the increasing of Al/O ratio and the detonation heat achieves a maximum value when Al/O ratio equals to 0. 997. When Al/O ratio equals to 0. 366, the peak pressure and shock wave energy reach the maximum value, but the shock wave impulse and flux density reach the maximum value when Al/O ratio equals to 0. 633 , and the first bubble pulsation period and radius reach the maximum values when Al/O ratio equals to 0. 997. [ABSTRACT FROM AUTHOR]

This study aimed to systematically evaluate the effect of traditional Chinese medicine(TCM) injections on anthracycline-induced cardiac injury. The Cochrane Library, PubMed, EMbase, CNKI, and other databases were electronically retrieved to gather randomized controlled trials(RCTs) of TCM injections against anthracycline-induced cardiac injury from their inception to September 2021. After two research fellows independently screened the literature and extracted the data, the risk of bias of included RCTs was assessed and network Meta-analysis was performed by R 4.1.0 and Stata 15.1. A total of 50 RCTs were included, involving eight TCM injections. Network Meta-analysis showed that:(1)the combination of anthracyclines with Huachansu Injection might be the optimal treatment to reduce the abnormal electrocardiogram.(2)The combination with Shenfu Injection might be the optimum treatment to ameliorate the left ventricular ejection fraction(LVEF) decrease.(3)The combination with Shenqi Fuzheng Injection might reduce the incidence of cardiotoxicity most satisfactorily.(4)The combination with Xinmailong Injection might improve the elevated cardiac troponin I(cTnI) optimally.(5)The combination with Shenmai Injection might be optimal to control the rise of creatine kinase MB isoenzyme(CK-MB).(6)The combination with Kushen Injection might be the regimen with the lowest gastrointestinal reactions. TCM injections had desirable effect on anthracycline-induced cardiac injury, with low incidence of adverse reactions, and each TCM injection had its own unique advantages. Due to the limitations in quality and methodological conduct of the included studies, more high-level RCTs are needed to validate the conclusions.