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Objective To explore the clinical characteristics of 2 668 inpatients in emergency ward, and to provide reference for emergency management. Methods Total of 2 668 patients hospitalized in the emergency department of xuanwu hospital from January 2015 to June 2018 were selected and the study data were retrospectively collected, including gender, age, comorbidities involvement system, hospitalization cost, length of hospital stay, and self-care ability score before hospitalization and before discharge. Results 1)The average age of male patients was younger than that of females (67.2±17.1 vs 70.7±17.2 years old)(P＜0.01). 2)2 408(90.25%) patients admitted to the hospital with more than 3 kinds of co-morbidities, and the co-morbidities involved mainly in respiratory, circulation, and endocrine systems. 3)The immediate living ability score was significantly lower than that before discharge (69.42±25.09 vs 78.12±26.13) (P＜0.001). 4)Barthel score was negatively correlated with length of stay, cost of hospitalization, decreased albumin, and anemia. Conclusions The types of diseases in the emergency ward are complicated, involving multiple disciplines and specialties, and the critical condition is variabl. Comprehensive and comprehensive evaluation is necessary in the process of clinical diagnosis, treatment and nursing care to improve the clinical outcomes of patients.