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In order to study the relationship between briquette preparation technique and performances and guide the optimization of the production technique, a single polarized microscope and digital images processing technology were applied to two aspacts study, which the total void features and the horizontal and vertical void distribution features of the briquette prepared with different quality binder and different pressure, and to the deep analysis on the void diameter, location, orientation degree and other features. The study results showed that the void rate of the briquette prepared with different quality binder and different pressure would be have big difference. The horizontal and vertical void rates of the briquette would be different and the horizontal void diameter would be concentrated. The void distribution of the briquette would be in homogeneous and the orientation degree would be poor. The void of briquette from the surface of the internal would be in an increasing tendency. [ABSTRACT FROM AUTHOR]

PURPOSE: Growing evidence shows an association between diabetes mellitus and alveolar hone loss. As abnormal cellular glucose uptake and metabolism are partly involved in diabetic complications, this study was undertaken to explore the effect of hyperglycemia on glucose uptake, glucose transporter1 (GLUT1) expression induced by insulin of rat mandibular osteoblasts. METHODS: Primary osteoblasts were isolated and cultured. The cells were incubated for 48h with medium containing 5.5mmol/L and 16.5mmol/L glucose respectively, then treated with or without insulin for 24h. Glucose uptake was detected by using 18F-FDG in the cells and GLUT1 expression levels were evaluated by Western blotting analysis. One-way ANOVA and t test were performed using SPSS13.0 software package. RESULTS: The results showed that with 16.5mmol/L glucose, glucose uptake was not changed significantly, hut GLUT1 expression was increased by 35% (P<0.01), insulin had no significant effect on glucose uptake, hut it decreased GLUT1 expression by 33% (P< 0.01). CONCLUSIONS: It is concluded that hyperglycemia can induce insulin resistance of osteoblasts, in which alteration in transport activity and function of GLUT1 might he involved. [ABSTRACT FROM AUTHOR]