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In this study, the interactions of six different flavonoids (IVa~c and Va~c) with bovine serum proteins (BSA) were investigated by fluorescence spectroscopy, thermodynamic and molecular dynamics simulations. The fluorescence behaviors of IVa~c and Va~c were quantitatively related to BSA, and the results calculated using the Stern-Volmer equation showed that IVa~c and Va~c had significant fluores-cence quenching with BSA, both of which were static quenching. The binding ability of monofluoroflavone with BSA was best when its fluorine atom was at para position, while the binding ability of monofluoroflavonol with BSA was best when its fluorine atom was at meta position. The binding ability of monofluoroflavonol with BSA was stronger than that of monofluoroflavone when hydroxyl group was attached to the C(3) of monofluoroflavone IVa~c. The calculated thermodynamic parameters of IVa~c and Va~Va were ΔG<0, ΔH<0 and ΔS<0, indicating that the interaction of IVa~c and Va~Vc with BSA was a spontaneous exothermic process, which mainly relies on hydrogen bonding and van der Waals force. [ABSTRACT FROM AUTHOR]

The anthropogenic volatile organic compounds (VOCs) emissions inventory in Jiaxing for 2015 was established by collecting comprehensive activity data of anthropogenic sources and adopting scientific and reasonable estimation methods and emissions factors. Results showed that the total VOCs emissions in Jiaxing for 2015 amounted to 10.21×10 4 t, of which 78.15%, 12.08%, 5.83%, 3.24%, 0.26%, and 0.44% was contributed by industrial sources, vehicles, domestic sources, oil storage and transport, waste disposal, and burning of agricultural crop residues, respectively. Packaging and printing industries, the surface coating industry, the dyeing industry, chemical materials manufacturers, and the petrochemical industry are the most important VOCs-emitting industries. Haining, Tongxiang, and Pinghu were the three cities with the highest emissions amounts, which contributed 50% of the total VOCs emissions. The average emissions intensity of VOCs in Jingkai, Haining, and Nanhu exceeded 30 t·km -2 .