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[Objective]The resistance classification to Bombyx mori cytoplasmic polyhediosis virtis(BmCPV) of the silkworm varieties from Yunnan sericultural areas were investigat in order to breed resistant variety and study key gene.[Method]On the basis of previous work, we selected 58 silkworm varieties to investigate the infection rate of BmCPV.The same concentration of BmCPV suspension liquid were fed on the 3rd instais larva, 7 days after inoculation, determining infection amount through microscopy and the data were analyzed by using analysis of variance, multiple comparison, and combination of clustering analysis.[Result]The results showed that the infection rate among different varieties were different significance(P <0.01), we obtained 4 variety classifications by K-Mean clustering analysis method, high resistant varieties were variety 10 and variety 14, high susceptible varieties were variety 23. We obtained 2 categories and 4 variety classifications by the method of system clustering tree, high resistant varieties had 5, high susceptible varieties had 10. [Conclusion] The resistant ability of 58 silkworm varieties to BmCPV from Yunnan seric ultural areas were divided into 4 levels according to the method of system clustering, high resistant varieties accounted for 9 % , high susceptible varieties accounted for 17 % , intemiediate levels of sensibility and resistance in 34 % and 40 % respectively. [ABSTRACT FROM AUTHOR]