Search

Background Sepsis is a systemic inflammatory response caused by an imbalance of the host immune response to infectious factors, potentially leading to life-threatening organ dysfunction. The application of immature platelet fraction (IPF) to assessing the severity and prognosis of sepsis has been previously analyzed. However, the application of IPF combined with other biomarkers to predict sepsis has been rarely reported. Objective To explore the predictive value of IPF combined with other biomarkers in the severity and prognosis of sepsis. Methods A total of 60 sepsis patients admitted to the Department of Critical Care Medicine, Zhongshan Hospital, Fudan University (Xiamen Branch) from November 2020 to November 2022 were retrospectively recruited for analyzing their clinical data. Patients were classified into the severe sepsis group (n=24) and septic shock group (n=36) based on the severity of sepsis. Divided by the Sequential Organ Failure Assessment (SOFA) score, 60 sepsis patients were assigned into the low SOFA group (SOFA score

Severe acute pancreatitis (SAP) is the most serious type of acute pancreatitis (AP) and a common critical disease in clinic. With the continuous improvement of medical level, the mortality rate in the early stage of SAP has decreased significantly, and the peak of death is mainly concentrated in the later stage of the disease and the main cause of death in the later stage is secondary sepsis after infection of pancreatic or peripancreatic necrosis. If the risk of secondary sepsis in SAP can be predicted early it can guide the medical staff to carry out appropriate early monitoring and intervention to improve the clinical outcome of patients, The article reviewed the application progress of blood markers to predict secondary sepsis in SAP. [ABSTRACT FROM AUTHOR]