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Objective: To investigate the allergens distribution of 576 allergic rhinitis patients in Qingyang, and to provide basic epidemiologic information for the prevention and treatment of allergic rhinitis., Method: Skin prick test was done to all the 576 patients with allergic rhinitis with 28 kinds of allergens., Result: Four hundred and eighty cases (83.3%) showed positive reaction to at least one allergen of 28 allergens. The most common allergens were Magwort (73.3%), Giant Ragweed (55.0%) Tree II (51.7%), Tree I (48.3%) Dermatophagoides farinae (43.3%) and Dermatophagoides pteronyssinus (36.7%). Moreover. the positivity decreased with age. There was no difference between male and female., Conclusion: The study shows that Magwort. Giant ragweed and tree II are the most important allergens on Qingyang district.

Objective: To investigate the variation of common allergens in patients with allergic rhinitis in recent 4 years in Tianjin First Center Hospital., Methods: The medical records of skin prick test on 3292 patients with allergic rhinitis between 2009 and 2012 were restrospectively analyzed. The changing trend of various allergens in 4 years and distribution differences were compared. The differences of the top 5 allergens in under age group, adult group and different gender group were further analyzed by SPSS 19.0 software., Results: The positive rate of dermatophagoides farinae was increasing year by year, from 45.1% in 2009 to 66.3% in 2012, and the positive rate of dermatophagoides pteronyssinus increased from 42.0% in 2009 to 58.6% in 2012, the difference was statistically significant (χ(2) value was 68.70, 41.55, all P < 0.01). The positive rate of dermatophagoides farinae and dermatophagoides pteronyssinus in adult group and male group showed significant upward trend year by year (χ(2) value was 75.85, 69.93, 274.25, 42.62, all P < 0.01), but not in adult group and female group. The positive rate of quinoa, mugwort and humulus scandens decreased year by year between 2009 and 2011(χ(2) value was 22.08, 11.64, 203.19, all P < 0.01), but increased again in 2012(χ(2) value was 21.55, 29.38, 12.40, all P < 0.01)., Conclusions: There is a tendency of change of allergens in patients with AR. This phenominon may be helpful for doctors to choose the type of skin prick liquid.

Objective: To investigate the inhaled allergens spectrum of 890 allergic rhinitis patients in Shanghai, and to provide basic epidemiologic information for the prevention and treatment of allergic rhinitis., Method: Thirteen allergens skin prick test results of 890 allergic rhinitis patients recruited were retrospectively analyzed., Result: The main common inhaled allergens in allergic rhinitis patients in Shanghai were house dust mite (91.24%), dermatophagoides farinae (86.58%), tropical mite (51.98%), dog hair (15.96%). Moreover, the positive frequency was decreased with age increasing, and gender group had no obvious difference., Conclusion: House dust mite and dermatophagoides farinae were the main allergens of allergic rhinitis patients in Shanghai. Skin prick test is helpful for the discovery of the allergens so as to provide important basis of immunotherapy.

OBJECTIVE This study aimed to determine the relationship between individual allergens with current wheezing and bronchial hyperresponsiveness (BHR) in schoolchildren from three chinese cities: Beijing, Guangzhou and Hong Kong. METHODS Community-based random samples of 10-yr-old schoolchildren from the 3 cities were recruited for study using the International Study of Asthma and Allergies in Childhood (ISAAC) Phase II protocol. The subjects were studied by parental questionnaires (n = 10,902), skin-prick tests (n = 3478), and methacholine challenge tests (n = 608). RESULTS The highest prevalence rates of wheezing in the past 12 months (Beijing, 3.8%; Guangzhou, 3.4%; Hong Kong, 5.8%) and atopy (Beijing, 23.9%; Guangzhou, 30.8%; Hong Kong, 41.2%, defined as having