1. 田间条件下玉米中甲氨基阿维菌素苯甲酸盐和吡丙醚的残留水平与膳食风险评估.
- Author
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秦世鹏 and 胡继业
- Subjects
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EMAMECTIN benzoate , *CORN seeds , *CORN straw , *PYRIPROXYFEN , *STANDARD deviations , *LIQUID chromatography-mass spectrometry - Abstract
[Objectives]This paper aimed to research on the residue behavior of emamectin benzoate and pyriproxyfen in field corn and evaluate the chronic dietary risk, so as to provide suggestions for the rational use of emamectin benzoate and pyriproxyfen on corn. [Methods]In accordance with good agricultural practices(GAP), the field trials of 12% microemulsion(3% emamectin benzoate+9% pyriproxyfen, ME)on corn were carried out across 12 regions of main corn production in China. The formulation of 12% ME was sprayed once at the dosage of 45 g·hm-2 during the incubation period of corn borer eggs, and the recommended pre-harvest interval(PHI)was 21 days. Meanwhile, a method for determination of emamectin benzoate and pyriproxyfen in corn was developed based on QuEChERS and high-performance liquid chromatography-tandem mass spectrometry(HPLC-MS/MS), which was applied to detect the residue levels in field corn samples, and the chronic dietary risk was assessed based on field trial results. [Results]At the spiked levels of 0.01, 0.05, 0.1 and 1 mg·kg-1, the mean recoveries of emamectin B1a and pyriproxyfen in fresh corn, corn kernels and corn straw samples were 87%-106%, with relative standard deviations(RSD)of 2.3%-7.5% and limits of quantification(LOQ)all being 0.01 mg·kg-1. In the fresh corn and corn kernel samples harvested at 21 and 28 days after application, the terminal residue levels of emamectin B1a benzoate were less than 0.011 mg·kg-1, which were lower than the maximum residue limit(MRL)of emamectin benzoate in corn in China(fresh corn:0.05 mg·kg-1; corn kernel:0.05 mg·kg-1), and the terminal residue levels of pyriproxyfen were less than 0.01 mg·kg-1(At present, the MRL of pyriproxyfen on corn had not been set in China). The chronic risk quotients of emamectin benzoate and pyriproxyfen were 78.4% and 5.8%, respectively, which were both lower than 100%, indicating a low risk to consumer's health. [Conclusions]Under the GAP conditions of applying 12% microemulsion(3% emamectin benzoate+9% pyriproxyfen)on corn, the recommended PHI of 21 days was safe. The paper could also offer a reference for China to formulate the MRL of pyriproxyfen on corn. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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