Search

Objective To investigate the levels and clinical significance of serum microRNA (miR)-651 and miR-630 in patients with cervical cancer. Methods From June 2017 to May 2020, 108 cervical cancer patients accepted by our hospital were collected as the cervical cancer group. Meantime, 100 cervical intraepithelial neoplasia (CIN) patients treated in our hospital were regarded as the CIN group, and 110 healthy individuals who underwent physical examination were regarded as the control group. Real-time fluorescence quantitative PCR (qRT-PCR) was applied to detect serum levels of miR-651 and miR-630, while analyzing the relationship between serum miR-651 and miR-630 as well as clinical features and prognosis of patients. Results The serum levels of miR-651 and miR-630 in the cervical cancer group and CIN group were obviously lower than those in the control group (P<0.05), while the serum levels of miR-651 and miR-630 in the cervical cancer group were obviously lower than those in the CIN group (P < 0.05). The expression levels of serum miR-651 and miR-630 were positively correlated (r = 0.542, P < 0.05). The serum levels of miR-651 and miR-630 were related to HPV infection, differentiation, lymph node metastasis, and FIGO staging (P < 0.05). The overall survival rate of patients with low levels of miR-651 and miR-630 was lower than that of patients with high levels. Cox regression analysis showed that, HPV infection, degree of differentiation, lymph node metastasis, FIGO staging, miR-651, and miR-630 were all influencing factors for the prognosis of cervical cancer patients (P < 0.05). Conclusion The serum levels of miR-651 and miR-630 in cervical cancer patients decrease, which are related to HPV infection, differentiation, lymph node metastasis, FIGO staging, and prognosis. [ABSTRACT FROM AUTHOR]

The appiication of recycled carbon tibres and ther composte mateflais have great economic value. The surface wettability of carbon tibres can be effectively improved after modifying of waterborne polyurethane sizing agent. Moreover, the interface integration iuation between carbon tibres and thermoplastic retins can be further enhanced. The experimental results show that the surface modmed recycled carbon tibre/ABS resin matrix composte exhibtts good tensle strength and elastic modulus. This article aims to enrich the rdevant research on recycled carbon fibre/thermoplastic reiin compoites, and provide rfferences bass for the subsequent surface reconstruction of recycled carbon tibres and the preparation of thermoplastic compostes. It is expected to promote the appiication of recyded carbon tibres in the industrial Held. [ABSTRACT FROM AUTHOR]

In order to improve the utilization rate of tobacco stems and the processing quality of stem shreds, the processing parameters of tobacco stems sorting, steam and microwave co-expansion, expanded tobacco stem remoisture, tobacco stem recutting, airflow drying and other key process parameters in the processing of microwave expanded tobacco stem shreds were studied. The optimal process parameters were as follows: tobacco stem sorting process selected short stems with a length of ≥2 cm and fine stems with a diameter of ≥3. 0 mm. The material flow rate in the steam-microwave co-expansion process was set at 240 ~ 270 kg/ h, the superheated steam flow rate was 950~1050 kg/ h, the cavity temperature was 148~151 °, and the microwave power was between 36~39 kW. When the water washing time in the moisture regaining process of expanded tobacco stems was greater than 50 s, the moisture content of Conditions was 30. 5% The storage time after conditioning was not less than 4 hours. The combination method of front high and low back was used in the re-cutting process of tobacco stems. The slice thickness was 0. 60 mm, the cutting width was 0. 30 mm, the knife door pressure was 30~35 kN, and the knife roller rotation speed was within the range of 400~450 r/ min. The material flow rate was 150 kg/ h, the process gas flow rate was 6500 m³ / h, and the temperature was 196 °. The width of the stalk processed by the silk-making process was closer to that of the leaf stalk, the stalk structure was more uniform, and the overall quality of the stalk was better. [ABSTRACT FROM AUTHOR]

Objective To explore the workload and job satisfaction of diabetes specialist nurses (DSN) in Chinese hospitals and clarify the influencing factors of job satisfaction. Methods From October to December, 2018, a total of 3 918 DSN were enrolled by using of convenient sampling method in China and demographic data. The current workload of DSN, and job satisfaction were collected using a self-designed questionnaire via WJX platform. Independent sample t test was used for the comparison between dichotomous variables, one-way analysis of variance (ANOVA) was used for the comparison between multiple categorical variables, Pearson correlation analysis was used for the correlation analysis of two continuous variables, and multiple linear regression method was used for the multivariate analysis of job satisfaction of DSN. Results A total of 1 920 (49.0%) DSN spent most of the time in diabetes-related work and only 975 (24.9%) were very satisfied. Multivariate linear regression analysis showed that regional, department, professional title, years of diabetes care, work capability enhancement after training, specialist nurses system, proportion of diabetes-related work, diabetes clinical nursing, diabetes education, consultations and providing guidance for primary diabetes care were the influencing factors of job satisfaction (β=-0.210, 0.046, -0.101, -0.008, 0.075, -0.160, -0.200, 0.051, -0.039, -0.046, -0.065, respectively, all P<0.05). Conclusion The proportion of diabetes-related work and job satisfaction need to be further improved. [ABSTRACT FROM AUTHOR]

Increasingly stringent discharge standards make it necessary to research and develop a new processes that have the advantages of relatively high efficiency, less land occupation, investigated savings, easy management, and maintenance for nutrient removal from the domestic sewage. An enhanced denitrifying phosphorus removal system was developed to treat domestic sewage, especially for the sewage with comparatively low carbon source and high nitrogen and phosphorus concentration. The system included an integrating anaerobic/anoxic/oxic (A2/O) reactor and a biological contact oxidation (BCO) (A2/O - BCO for short). The A2/O unit consisted of four compartments in sequence with a working volume of 40L. It was mainly used for the removal of organic compounds and nutrients without ammonium oxidation, while the BCO unit was mainly responsible for nitrification. The BCO unit, with 24L working volume, consisted of three compartments in sequence, where suspended carriers were filled in it, with packing rates of 45% in each zone. The removal of biological nitrogen (N) and phosphorus (P) were investigated in an A2/O - BCO nitrogen and phosphorus removal process when treating domestic sewage. The experiment was carried out with the influent flow at a rate of 5L/h, total hydraulic retention time (HRT) of A2O about 8 h, sludge reflux ratio of 100%, sludge retention time (SRT) of 12d, MLSS maintained at 3500 mg/L, total HRT of BCO about 1.9 h, DO should be controlled within a reasonable range, and nitrate recycling ratios were set as 100%, 200%, 300%, and 400% respectively. Based on the experimental data under steady state operating conditions of different nitrate recycling ratios, the equations for calculating material balances of COD, nitrogen, and phosphate were established. These three material distributions in the system were also evaluated. The result indicated that the process has an advantage of making full use of the raw water carbon and removing biological nitrogen and phosphorus deeply. With the nitrate recycling ratios of 100%, 200%, 300%, and 400% conditions, the system COD was mainly utilized in the anaerobic stage in A2/O reactor, and removal percentages of total COD were 78.5%, 71.8%, 57.9%, and 71.1% respsectively. Nitrogen removal was mainly achieved by denitrifying in the phosphorus removal process by denitrifying phosphorus bacteria. The denitrification removal ratios of the total amount were 28.0%, 35.7%, 48.5%, and 33.9%, respectively. Phosphorus removal was mainly achieved by the discharge of excess sludge, where the amount of phosphorus percentages of total were 78.0%, 88.4%, 84.3%, and 85.4% respectively. Under the different nitrate recycling ratios, COD balance ratios were 96.4%, 99.6%, 98.7%, and 98.3%, nitrogen balance ratios were 99.7%, 98.2%, 99.2%, and 96.5%, and phosphorus balance ratios were 92.0%, 98.1%, 93.3%, and 90.4%. Fluorescence in situ hybridization showed that the anammox bacteria existed in the biofilm of BCO, and its proportion of the total bacterial number was 0.6∼2.7%. The nitrogen loss may be due to the occurrence of the anammox reaction. The amount of denitrifying phosphorus increased slightly with the nitrate recycling ratio improved. But it is essential to control nitrate recycling ratio in the appropriate range to ensure nitrogen removal efficiency. The system achieved the best removal efficiencies of nitrogen and phosphorus when the nitrate recycling ratio was set as 300%, in which the average concentrations of TN and TP were 14.96 mg/L and 0.49 mg/L respectively in the effluent, which met the class of a limit (GB18918-2002) of the discharge standards. This study not only contributes to a better understanding and analysis of distribution and changes about organics, nitrogen and phosphorus in process systems, but also provides a theoretical basis and guidance for the reliability evaluation of the of the experimental data by building a mathematical model. The combined A2/O - BCO process will get a better promotion in treating domestic wastewater, especially the rural domestic wastewater with the universal features of small quantity, scattered distribution, and water fluctuation. [ABSTRACT FROM AUTHOR]