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BACKGROUND: Soft silicone silver ion dressing, a kind of high molecular weight organic compound prepared with Safetac technology, has the characteristics of anti-infection, good permeability and good air permeability. It can provide a good moist environment for wound healing. OBJECTIVE: To evaluate the effectiveness of soft silicone silver ion dressings in repairing deep II degree and milder bum wounds. METHODS: A computer-based retrieval of CNKI, VIP, WanFang, CBM, PubMed, Embase and Web of Science databases was performed. The randomized controlled trials conceming soft silicone silver ion dressing for repairing deep II degree and milder bum wounds were selected. The treatment group was treated with a single soft silicone silver ion dressing, or a soft silicone silver ion dressing combined with conventional treatment, or combined with other treatments. The control group was treated with conventional treatment, or other treatments, or placebo. After screening, data extraction and quality evaluation, meta-analysis was performed using Review Manager 5.3 software. RESULTS AND CONCLUSION: (1) Eleven articles were included, involving 784 patients, 381 patients in the treatment group and 403 patients in the control group. (2) The results of meta-analysis showed that the bum wound healing rate in the treatment group was higher than that in the control group [OR=11.56, 95%Cl (9.60, 13.53), P < 0.000 01; OR=13.29, 95%Cl (7.54, 19.04), P < 0.000 01; OR=4.10, 95%Cl (2.28, 5.93), P < 0.000 1; OR=1.17, 95%Cl (0.42, 1.93), P=0.002] at 7, 14 and 21 days, and the last measurement. The healing time of bum wounds in the treatment group was shorter than that in the control group [OR=-2.81, 95%Cl (一3.49, -2.12), P < 0.000 01]. The degree of pain in bum wounds in the treatment group was lower than that in the control group [OR=0.38, 95%Cl (-0.53,一0.24), P < 0.000 01]. There was no significant difference in the positive rate of bacterial culture on wound surface [OR=1.16, 95%Cl (0.47, 2.85), P=0.74], bum wound infection [OR=1.44, 95%Cl (0.47, 4.41), P=0.52], dressing frequency [OR=-8.04, 95%Cl (-18.82, 2.74), P=0.14], wound treatment cost [OR=-98.26, 95%Cl (-272.91, 76.40), P=0.27] and adverse reaction [OR=0.61, 95%Cl (0.31, 1.20), P=0.15] between treatment and control groups. (3) These results show that the application of soft silicone silver ion dressing on deep II degree and milder bum wounds can improve wound healing rate, shorten wound healing time and alleviate pain. [ABSTRACT FROM AUTHOR]

BACKGROUND: At present, platelet-rich plasma has been used in bums, plastic surgery, surgery and orthopedics. However, due to the different standards for platelet-rich plasma preparation, the results of research on bums are controversial. OBJECTIVE: To systematically evaluate the effectiveness of platelet-rich plasma in the repair of bum wounds. METHODS: A computer-based online search of CNKI, VIP, WanFang, CBMdisc, PubMed, Embase, Cochrane Library, Web of Science databases to retrieve randomized controlled trials regarding platelet-rich plasma repair of bum wounds. In the treatment group, platelet-rich plasma therapy or platelet-rich plasma therapy combined with conventional or other therapies were used. In the control group, conventional therapy, other therapies, or placebo treatment were used. After literature screening, information extraction and quality evaluation, Review Manager 5.3 software was used for meta analysis. RESULTS AND CONCLUSION: Eleven articles were included, involving 837 patients consisting of 420 patients in the treatment group and 417 patients in the control group. Meta analysis results revealed that the wound healing rate in the treatment group was significantly higher than that in the control group [OR=12.61, 95%C/ (6.93, 18.29), P < 0.000 1]. Wound healing time in the treatment group was significantly shorter than that in the control group [OR=-4.64, 95%C/ (-6.21, -3.06), P < 0.000 01]. The number of layers of gauze soaked by dressing [OR=-4.01, 95%C/ (-4.91, -3.11), P< 0.000 01], the times of changing inner gauze [OR=-3.79, 95%C/ (-5.33, -2.26), P < 0.000 01, and the times of dressing change on wound surface [OR=-3.41, 95%C/ (-5.93, -0.88), P=0.008) in the treatment group were significantly less than those in the control group. The positive rate of bacterial culture in wound [OR=0.46, 95%C/ (0.22, 0.94), P=0.03] and the incidence of inflammatory reaction in wound [OR=0.30, 95%C/ (0.17, 0.56), P=0.000 1) in the treatment group were significantly lower than those in the control group. The results suggested that platelet-rich plasma can increase the wound healing rate, shorten wound healing time, reduce the number of layers of gauze soaked by dressing, the times of changing inner gauze, and the times of dressing change on wound surface, and lower the positive rate of bacterial culture and the incidence of inflammatory reaction in wound. [ABSTRACT FROM AUTHOR]