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The proposal of a national strategy for the "New Western Land Sea Corridor" will affect the reconstruction of the overall freight distribution pattern in western China. As the most important hub node for cargo distribution and transshipment in inland areas, the inland port (or dry port) is of great significance to regional economic development, logistics systems, and the construction of a new regional development pattern. Therefore, 111 papers on inland port research in international core journals have been selected in this study to systematically review the research status of inland ports and put forward the key directions and development trends for future research to serve the theoretical research and construction planning practice of inland ports in China, and globally. In this study, the literature metrology method is adopted to divide inland port research and development into three stages: the first stage is the initial stage (before 2005); the second stage is the slow fluctuating growth stage (2006-2017); the third stage is the rapid increase stage (2018-present). Scholars are interested in inland port research mainly from mainland China, the Netherlands, Hong Kong, the United Kingdom, the United States, and other countries (regions). Related research topics on inland ports are mostly combined with transportation, logistics, and other fields, which indicates that inland ports have become an important part of transportation systems and supply chain transportation networks. Among specific related research topics, the concept of inland ports is an important research topic, mainly focusing on the differences in naming and function, facilities of inland ports under different geographical backgrounds, and additional functions extended with economic development; however, its concept has not yet been unified. Research on the spatial layout system of inland ports shows that the inland port site selection and layout can be roughly summed up as a supply chain-oriented pattern, and industrial cluster-oriented pattern; the former often near port cargo distribution of traffic nodes, while the latter is on the border between the end of the supply chain. The location and layout of inland ports are influenced by economic foundation, transportation infrastructure, and local policy factors. Inland ports have a profound impact on the region. In terms of spatial effects, they have an impact on urban spatial planning and land use; in terms of economic effects, they can promote regional economic development and employment; in terms of environmental effects, they can reduce energy consumption and emissions, and promote the realization of regional sustainable development. In the operation and control of inland ports, special attention should be paid to the relationship between port planning and each manager, as well as to the management system, to realize the efficient, sustainable, and healthy development of inland ports. Finally, based on the new trends of global inland port logistics research and the realistic demand of China, we put forward several suggestions for future research, including the redefinition of dry ports, spatial layout and planning of inland ports, their regional influence, the port-city relationship, risk of investment, and potential benefits of inland ports. [ABSTRACT FROM AUTHOR]

This study used bibliometrics to analyze the characteristics of funded papers in the social sciences in Taiwan from 2015 to 2019, including the number of funded papers, funded paper ratio, document types, fields, type of publishing organizations, journal impact, and paper citation impact. The results indicate that the number of funded papers and the funded paper ratio of SSCI papers from Taiwan have both increased. In addition to articles and reviews, conference papers are a major type of funded paper for local SSCI papers. In terms of fields, the nontraditional social sciences, such as environmental sciences, psychiatry, and public/environmental & occupational health, have a particularly high funded paper ratio. However, the number of funded papers and funded paper ratio is the highest in the field of education & educational research. The fields of economics, management, and business have a large number of funded papers but a low funded paper ratio. Universities are the main funded institutions, but hospitals have the highest funded paper ratio. Funded papers tend to have higher paper citation impacts. Therefore, funding positively affects the productivity and impact of SSCI papers from Taiwan. [ABSTRACT FROM AUTHOR]

[Purpose/Significance] "The Belt and Road" is an initiative proposed by China in recent years to cooperate and develop a community with a shared future for mankind, which has been continuously highly concerned by all circles at home and abroad. From the perspective of the citation of highly cited papers, the academic exchange of countries along the Belt and Road initiative cam provide a quantitative reference for future international academic and technological exchanges, collaborative innovation and development. [Method/Process] Based on the highly cited papers among the countries along the "The Belt and Road" in the WoS database from 2013 to 2018, this paper constructed a reference matrix and analyzed the network structure, and drew a national citation network map for cluster division. Furthermore, it explored the current state of academic exchange along the "The Belt and Road" and the direction of Chinese academic output, and further analyzed the correlation between Chinese academic exchanges and trade cooperation with other 64 countries along the route. [Results/Conclusions] The research results show that the countries along "The Belt and Road" have close academic exchange and obvious "small world" characteristics. China is the core of academic exchange and the highly cited papers in many research directions in China are cited by many countries along "The Belt and Road". Besides, academic exchange and trade cooperation between China and countries along "The Belt and Road" are strongly related. [ABSTRACT FROM AUTHOR]

Objective A bibliometric analysis of the literature related to stroke and the blood-brain barrier was conducted to obtain a research map, explore hotspots and trends, and provide references for clinical treatment and research. Methods The literature related to stroke and blood-brain barrier from 1 January 2001 to 28 February 2023 was explored in the Web of Science core database. Using bibliometrics, CiteSpace V6.1.R6 was used to analyze the distribution of years, countries/regions, research institutions/system, authors, publications, cited literature, keywords and research trends. Results A total of 5028 papers were included after screening, with an overall upward trend in the number of published papers. The United States had the most research on this topic, followed by China’s mainland and Germany. Most of the top 10 research institutions/system were from the United States, France and China, with strong collaboration between countries/regions and research institutions/system. Among the authors, Chopp Michael from the United States ranked first with 49 papers. Among the research trends, ischemic stroke, miR-126 in non-coding RNA, blood-brain barrier dysfunction and drug delivery were the hot spots in the last three years. Conclusions Blood-brain barrier and stroke are inextricably linked. The dysfunction and repair mechanism of blood-brain barrier during stroke, the circulation biomarkers released by blood brain barrier and the use of blood-brain barrier opening time to increase drug absorption are worthy of further study [ABSTRACT FROM AUTHOR]

[Objective]. The aims of this article are to intuitively grasp the progress and hotspots in the field of research of gully erosion in the northeast of China black soil region, advance the development of research in gully erosion in the black soil region of northeast China. [Methods] 245 papers in CNKI and Web of Science databases were used to create a knowledge map of gully erosion in the black soil region of northeast using the bibliometric method and CiteSpace software. [Results] (1) Research on gully erosion in black soil area started late, and the number of published papers has increased significantly in the past 10 years, but the results published in international journals are few, accounting for only 26%. (2) The research institutions in this field mainly distribute in northeastern China, of which several institutions include Songliao Basin Committee of Ministry of Water Resources, Beijing Normal University, Northeast Institute of Geography and Agroecology of Chinese Academy of Sciences, Northeast Agricultural University, and Shenyang Agricultural University have made the outstanding contributions and shown the great influence in the field; Prof. Zhang Shuwen is the scholar with the most publications in Chinese, and Prof. Liu Baoyuan and Wu Yongqiu are the scholars with the most publications in English in this field. (3) The co-occurrence of keywords between the published literatures indicates that the current focus of attention on gully erosion in the black soil area of northeast China is mainly on the development characteristics, influencing factors and prevention and control measures of gully erosion. [Conclusion] The comprehensive research framework and a full understanding on gully erosion in the black soil region of northeastern China have not yet been established. In future research, there is a need to further emphasize the study of the formation and development processes and mechanisms of gully erosion in the black soil region of Northeastern China, and to conduct in-depth analyses of the influences of geological, topographical, hydrological, and human activities, among other factors. [ABSTRACT FROM AUTHOR]

Objective To analyze the current research status, hotspots, and frontier fields of perivascular spaces from 2013 to 2023 based on bibliometric analysis. Methods The related English article of perivascular spaces was retrieved in the Web of Science Core Collection from January 1, 2013 to June 19, 2023. CiteSpace V6.3.R1 software was used to analyze the cooperation network among the publishing countries, institutions and authors; the co-citation network of reference, first author of reference and journals; the co-occurrence network of keywords, burst analysis of keywords and reference co-citation. VOSviewer 1.6.15 software was used for keywords cluster analysis. Results A total of 1549 papers were included. The annual publications from 2013 to 2023 showed an overall increasing trend. The United States ranked the first and China ranked the second. The top three prolific institutions were Harvard University, Massachusetts General Hospital and University of Edinburgh. Cooperative network analysis showed that the cooperation between countries was close and domestic institutions collaborated less with other institutions. Wardlaw Joanna M from University of Edinburgh ranked the first in publications. The top ten keywords in co-occurrence network were small vessel disease, enlarged perivascular spaces, MRI, brain, Virchow-Robin spaces, Alzheimer’s disease, dementia, risk, stroke and glymphatic system. Cluster analysis of keywords showed that cerebral small vessel disease, dementia and MRI were current hotspots, and glymphatic system was a new research direction. Burst analysis of keywords suggested diffusion imaging has got much attention since 2021. Conclusions The research on perivascular spaces has increased during the recent 10 years. Cerebral small vessel disease was the main hotspot and glymphatic system was a new direction. Diffusion tensor imaging was a frontier field. [ABSTRACT FROM AUTHOR]

The study utilizes bibliometrics to explore papers and patents in the field of fuel cell to examine the scientific and technical development in the area. The research data were retrieved from the WOS database and USPTO patent data from the period between 1991 and 2010, which consists of 20,758 papers and 8,112 patents. The authors analyzed numbers of papers and patents to examine the trends in the papers and patents in different countries, organizations and individuals. The results indicate upward growth in both papers and patents in fuel cell, with a higher growth rate for papers. The study shows that major paper and patent output are concentrated in a small number of countries. An imbalance exists between the number of papers published and the patents granted in organizations. The organizations that published papers and patents vary in type and category. Very few individual researchers are able to produce high numbers of both papers and patents. [ABSTRACT FROM AUTHOR]

Objective To summarize the research progress and hotspots of traditional Chinese medicine (TCM) in the treatment of pulmonary fibrosis (PF) and provide references for future research. Methods Literature regarding TCM treatment for PF retrieved in the CNKI database from January 1, 1995 to January 1, 2023 was selected. The VOS viewer was utilized to conduct visualized analysis, and current and future potential hotspots and directions were proposed. Results A total of 794 related papers were included. The number of articles on TCM for treating PF showed an upward trend annually, peaking in 2020. Beijing University of Chinese Medicine published the most papers in this field. The top 10 keywords were idiopathic pulmonary fibrosis (375 times), pulmonary fibrosis (314 times), TCM (262 times), clinical research (58 times), pathogenesis (55 times), bleomycin (40 times), TGF-β (28 times), atrophic lung disease (31 times), epithelialmesenchymal transition (26 times), and Buyang Huanwu Decoction (26 times). In the past 3 years, the treatment direction has shifted from TCM formula to single herbs. The research focus of traditional Chinese medicine in the treatment of pulmonary fiber is in the fields of etiology, pathogenesis, and clinical research. Conclusions Recognition of TCM in treating PF is gradually increasing. Related research has transformed to focus more on single Chinese herbs. [ABSTRACT FROM AUTHOR]

Objective To understand the research hotspots and research trends about convolutional neural networks in the field of oncology imaging diagnosis by analyzing the characteristics of published literature at home and abroad over the past decade. Methods The SCI-E database was used as the data source to retrieve literature about convolutional neural networks in the field of oncology imaging diagnosis published from 2012 to 2022. The distribution characteristics of countries, institutions, journals, co-cited authors, and keywords of the studies were analyzed by CiteSpace software. Results A total of 1088 papers were eventually included, and they were mostly from China, the United States, and India. A total of 39 papers were published by Sun Yat-sen University, the research institution with the highest number of publications. Radiology Nuclear Medicine Medical Imaging was the journal with the highest number of publications. A total of 25 high-frequency keywords and 15 burst keywords were obtained. The formation of 12 author co-citation clusters such as image segmentation and lung nodule, as well as 11 keyword clusters such as automatic segmentation and breast cancer, was observed. Conclusion Current research on convolutional neural networks for oncology imaging diagnosis focuses on oncology segmentation, lung-nodule recognition, assisted diagnosis of breast cancer, and other high-frequency oncology. [ABSTRACT FROM AUTHOR]

Objective To explore the research status, hotspots, and trends in the field of stroke genetics and genomics according to bibliometric analysis on published literature since publication of the working draft of human genome. Methods The last two period (from 2000 to the present) was divided into 3 stages based on representative genomic technologies, namely first-generation sequencing (2000—2007), wholegenome genotyping microarray (2008—2015), and next-generation sequencing (2016—now). All of the published literature (written in English) on cerebrovascular disease genetics and genomics were retrieved from core collection of Web of Science. Year of publication, country/area, and institution of the literature were summarized. VOSviewer 1.6.18 was used for statistical and visual analysis. The H-index was used to evaluate the quantity and the impact of the literature. Results A total of 8833 English literature was included in this analysis. The United States was the main contributor to the literature on stroke genetics and genomics, and published 3291 articles with an H-index of 182, both ranking first in the quantity and H index of papers. China published 1765 papers with an H-index of 66, ranking second in the quantity and tenth in H-index. The International Stroke Genetics Consortium (ISGC) was an important contributor in this field of stroke genetics and genomics. ISGC and its principal directors ranked among the top 20 authors in the number of publications. The hotspots gradually shifted from association analysis and metaanalysis in the early stage to Mendelian randomization in recent years. Conclusions In the field of stroke genetics and genomics, although our country started late, there is a trend of catching up in the total number of publications. Clinical and scientific researchers in China should strengthen domestic and international academic cooperation to further enhance the China’s influence in this field. [ABSTRACT FROM AUTHOR]

Objective Based on bibliometrics, CiteSpace software was used to analyze the current research status and hot issues in the field of caregivers of stroke patients at home and abroad, to provide reference for further research in this field. Methods The relevant literature in the field of caregivers of stroke patients was retrieved from the China National Knowledge Network (CNKI) and Web of Science database from the database inception to December 31, 2021. The types of articles included clinical trials, reviews, dissertations and conference papers. Bibliometric analysis was conducted in terms of the number of papers, authors, institutions, countries and keywords. Results A total of 1298 Chinese and 1763 English literature were included. The number of these published articles is on the rise year by year both at home and abroad. In the database of CNKI, the number of published articles increased from 4 in 2002 to 164 in 2021. Zhang Zhenxiang of Zhengzhou University published the most (48 articles), and the Nursing and Health College of Zhengzhou University published the most (50 articles). In addition to the subject words, "influencing factors" "caring ability" "caring burden" "depression" "anxiety" and "self-perceived burden" were high-frequency keywords. In the Web of Science database, the number of published articles increased from 103 in 2009 to 201 in 2021, and the United States published the most (565 articles); Dr. ROTH D L of Johns Hopkins School of Medicine published the most; the Univ Toronto had the most publications (55 articles). "Quality of life" "rehabilitation" "support" "burden" "care" "depression symptom" and "survivor" were high-frequency keywords. Conclusion The research on caregivers of stroke patients at home and abroad was in a stable development stage in the recent ten years. The authors and institutions of these papers were all characterized by universities and regions, and lack of cross-regional and cross-unit cooperation. Domestic and foreign research hotspots were different. The influencing factors of caring burden and caring ability, and negative emotion of stroke caregivers were hot issues in China. The influencing factors of stroke caregivers' quality of life, caring burden and depressive symptoms of caregivers, and the influence of rehabilitation led by caregivers on stroke patients were hot issues abroad. The clinical and research workers should strengthen the cooperation among research institutions, pay attention to the research frontiers and hotspots, to improve the depth and breadth of research. [ABSTRACT FROM AUTHOR]

Objective Analyze the current situation, hotspots and development trends of sarcopenia animal model to provide research direction and basic information for sarcopenia animal model research. Methods English literature of research on animal models of sarcopenia was retrieved from the Web of Science core data (WOS) set from 1900-01-01 to 2022-12-31. Chinese literature related to animal models of sarcopenia was retrieved from CNKI database between 1915 and 2022. The bibliometric analysis software VOSviewer was used to explore the countries, orgonizations, authors, hotspots and frontier directions in these studies. Results A total of 2 819 articles on animal models of sarcopenia were retrieved from WOS core database. The first paper was published in 1995. The United States has the largest number of animal model studies of sarcopenia with 1 105 articles. The institution with the most published articles is the University of Florida in the United States, with 69 articles. The University of Hong Kong has the highest number of publications in China, with 20 articles. American author Van Remmen H, with 50 publications, is the author of the most articles. The journal with the largest number of articles published on animal models of sarcopenia is the American journal called FASEB Journal, with 196 articles. In total, 423 articles on animal models of sarcopenia were retrieved from the CNKI database. Author LI Zhuyi has published 19 articles, and is the author of the most articles in China. The keyword co-occurrence clustering analysis of WOS literature search found that the research focus on animal model of sarcopenia can be summarized as the correlation between sarcopenia and metabolism, cytology and regenerative medicine of sarcopenia animal models, the study of sarcopenia animal models in bone, muscle, nerve and exercise therapy. The retrieval results of CNKI database revealed that the most extensive research was about on the model of denervated sarcopenia, and researches on the effects of Chinese medicine on sarcopenia were also widely reported. Through reading the full articles or abstracts of the literature, the animal models of sacopenia mainly include natural aging model, genetic modification model, high-fat diet induction model, disuse model, hormone induction model and complex sarcopenia models of other diseases. Conclusion In recent years, the study on animal model of sarcopenia has become a hotspot at home and abroad. The bibliometric analysis provides a basis for the research of animal models of sarcopenia in terms of research direction, hotspots, model animal selection, animal model making, and domestic and international communication and cooperation. [ABSTRACT FROM AUTHOR]

A series of debates about health, ecology, and livestock production have been erupted in Taiwanese society since August 2020, following a decision by Taiwan's government to allow the importation of pork containing ractopamine from the United States. It becomes necessary to understand how the academic research results on ractopamine have been quoted and interpreted as the basis for discussing the debates. In this systematic review of literature along with bibliometrics, we designed a coding scheme for judging the positive and negative effects of ractopamine on health and ecology reported in the academic papers. A total of 511 articles were found in the Scopus between 2000 and 2020. According to the literature review, human health and ecological concerns are not the focus of mainstream academia. The analyses reveal that the positions of academic communities are obviously divided and lack consensus on the health and ecological stance of ractopamine. The mutual use of systematic literature review and bibliometrics can effectively explore the research characteristics of a huge amount of academic literature with limited time and research manpower, create a common knowledge base for stakeholders, and practice low-cost democratic participation in science and technology issues. This research suggests that for any controversial and risk-related technology policies, or in the early stages of policy discussion, a large-scale academic literature review should be conducted by a third-party organization in order to achieve transparent governance. [ABSTRACT FROM AUTHOR]

BACKGROUND: With the continuous accumulation of data resources around the world, the application of data visualization has become more urgent, and the methods of data visualization have also shown diversified characteristics. Data visualization is a scientific and technical research on the visual representation of data, which studies how to display relatively obscure data visually in a real and accurate way, to vividly and intuitively express the information and rules contained in the data. Literature is an important carrier of knowledge dissemination, with systematic characteristics, continuity, a large quantity and fast update, and is an important source of information. The visualization research of literature is of great significance to the dissemination of knowledge. At present, the visualization research of document data is mostly combined with the bibliometric analysis method, which visualizes the relationship between documents in the form of a scientific knowledge map. The application of this technology and method has played an important role in mining the information and rules contained in document data, but it is slightly insufficient in the spatial attribute mining of document data, which requires in-depth research in this field. OBJECTIVES: To provide new solutions for expanding the application of literature data in the field of spatial visualization, thereby further enhancing the usable value of literature data. METHODS: GIS technology was used to carry out the research on the spatial visualization method of document data, excavate the common content features and spatial features of document data, and gather the structured document data of a certain volume of spatial feature information to lay the data foundation for the visualization research. At the same time, the combination point between GIS technology and document data was studied, and the strategy and technical route for information mining and spatial visualization of document data were formed. Taking the data of more than 140 Re-Os isotope dating documents published since 2015 to 2020 as an example, the application test of this technical method was carried out. A Re-Os isotope data visualization service system with a five-tier architecture including layers of support, data, service, application and user has been developed, to realize the spatial visualization application of Re-Os isotope dating document data results. RESULTS: The results show that: (1) The study area contains more than 140 ore producing areas that carried out Re-Os isotope dating research from 2015 to 2020, covering the eastern, central, and western regions of China. (2) There are 19 main minerals in the study area, mainly copper (29. 0%), molybdenum (28. 3%), tungsten (12. 4%) and gold (11. 0%). (3) There are 12 kinds of detection objects, and the proportion of molybdenite as the detection object is 80. 7%, which indicates that molybdenite is still the preferred research object of the Re-Os isotope dating method, which is inseparable from the high Re / Os value of molybdenite. (4) The detection age falls in the lower age range of 0 - 200Ma, accounting for 62. 1% of the ore - producing areas, which are mainly distributed in the northeast and southeast regions of China, indicating that the Re-Os isotope ages in the eastern region are concentrated in the Mesozoic era, which is consistent with the existence of large - scale Mesozoic mineralization events in the eastern region of China. The ore - producing area in the age range above 200Ma accounts for 37. 9%, which is mainly distributed in the central and western regions of China, indicating that the Re-Os isotope ages in the central and western regions are concentrated before the Mesozoic era and have the characteristics of multiple mineralization. CONCLUSIONS: The research shows that the document data visualization technology and method proposed in this paper can be used to excavate the spatial characteristics of the document data, expand the application of the document data in the field of spatial visualization, and solve the problems of how to analyze and extract the common information of the document data, locate the spatial feature information, and realize the spatial visualization technology. In terms of revealing important target areas, key research minerals and main application technologies, it can provide spatial visualization information, and provide reference for finding the hot spots and difficulties of current metallogenic chronology research. [ABSTRACT FROM AUTHOR]

Objective To review the research progress, present the research status and analyze the evolution trend of hot spots through the bibliometric analysis of the research literature of cancer-related fatigue(CRF) at home and abroad. Methods We took CRF as the theme and the papers on CRF included in CNKI and WOS core database as the research object, and used VOSviewer and CiteSpace software as research tools, to make a visual atlas analysis on the research status and hot spot evolution at home and abroad. Results (1)Research status:①Literature: 3 646 papers (1 959 in English and 1 687 in Chinese) were finally included. The number of papers published at home and abroad showed an overall upward trend, and the proportion of foreign fund papers was high; ②domestic papers focused on nursing and rehabilitation. The research area of foreign papers was more extensive, diverse and integrated; ③Domestic cooperation was mainly small group cooperation, while foreign cooperation was more interdisciplinary and cross-team cooperation, forming a number of core teams and research institutions; ④ Domestic scholars paid attention to clinical application research and were good at learning from foreign countries and summarizing own experience. Foreign scholars paid more attention to basic research and the treatment was more systematic and standardized; ⑤There were a variety of diagnostic and therapeutic evaluation tools, mainly foreign scales. (2) Hot spot evolution: "quality of life" had always been a common topic of concern at home and abroad. Domestic scholars focused on clinical research and emphasized "treatment based on examination of causes" and "treatment based on syndrome differentiation". Foreign scholars attached importance to basic research and methodological research, and advocated non-drug intervention such as sports. In recent years, complementary and alternative medicine had become a hot topic in the international research. Domestic scholars had paid more attention to the research of mechanism and methodology, and expanded the application of TCM characteristic therapy in CRF. Conclusion Integrated traditional Chinese and Western medicine and multi-disciplinary participation are the future diagnosis and treatment mode of CRF. It's the direction of future efforts to establish CRF evaluation and management mode with TCM characteristic non-drug therapy as the core under integrated medicine. [ABSTRACT FROM AUTHOR]

Objective To investigate the current status and hotspots of Mendelian randomization (MR) studies in the field of ischemic stroke (IS), and to provide reference for future research directions, digging directions of drug targets and exploring mechanism. Methods The MR related English literature in the field of IS in the Web of Science Core Collection was retrieved up to September 2022. CiteSpace was used for cooperation network analysis among countries, institutions and authors, co-citation analysis of literature, co-occurrence and cluster analysis of keywords. Drug development of biomarkers casually linked to IS was inquired by the PharmSnap Global New Drug Database. Results A total of 200 articles were retrieved, and these studies entered a stage of rapid development in 2018. England had 80 articles, with intermediary centrality of 0.37 and 27 cooperation countries, while the US had 63 articles, with intermediary centrality of 0.10 and 21 cooperation countries or territories. All of the above data were in the top three of all countries or territories, making England and the US research centers in this area. China has published 106 articles, only with 16 cooperation countries or territories. Rainer Malik from Germany had published 20 papers, with 552 citation and 25 co-authors, all ranking the first. IL-6 was the only biological factor defined as a cluster label in the keywords clustering graph, and “inflammation” was the second most studied risk factor for IS in the keywords co-occurrence graph in the last three years. Among the 12 biomarkers of IS identified by MR, coagulation factor Ⅺ and lipoprotein (a) were the more promising drug targets and relevant drugs have entered clinical trials phase. Conclusions MR studies in the field of IS were carried out mainly in European countries or territories represented by England, the US and China. Inflammatory factors such as IL-6 were major research hotspots, and related studies provided evidence for biomarkers, such as coagulation factor Ⅺ and lipoprotein (a), as drug targets. [ABSTRACT FROM AUTHOR]

Objective To analyze the current research status, hotspots, and frontier fields of genomics studies on the prognosis of ischemic cerebrovascular disease (ICVD) from 2017 to 2022. Methods The related English literature of genomics in the field of ICVD was retrieved in the Web of Science Core Collection (SCI-EXPANDED) from January 1, 2017 to October 1, 2022. CiteSpace software was used to analyze the cooperation network among the publishing countries, institutions and authors; the co-citation network of reference, first author of reference and journals; clustering results of references; the co-occurrence network of keywords and their clustering results. The results were presented by visual maps. Results A total of 353 papers were included in this study. China ranked the first in the world with 144 articles, but only with five countries with cooperation partnership. Capital Medical University was the most prolific institution, with 20 articles. Six of the top ten authors were from members of the International Stroke Genetics Consortium (ISGC), who were the main contributors and formed major cooperation clusters. Genome-wide association analysis (GWAS) and Mendelian randomization were the most commonly used research methods. In recent years, the hotspots focused on exploring the common genetic pathways of stroke prognosis and other complex diseases, genetic variation affecting the efficacy of antiplatelet drugs, and the influence of inflammatory mechanism on prognosis. Conclusions The genomics studies of ICVD prognosis, which explore the underlying mechanism to facilitate new drugs development, have gained the popularity year by year and formed several research hotspots. [ABSTRACT FROM AUTHOR]

Background and objective: Cardio-oncology that focuses on the management of cardiovascular toxicity associated with cancer therapy, has grown rapidly worldwide as an emerging interdisciplinary discipline over the past decade. This study aimed to summarize the hot spots and development trends of cardio-oncology to provide a reference for scientific researchers in related fields based on bibliometrics. Methods: CiteSpace was employed to conduct the visualized analysis of annual publications, authors, countries, citations and keywords of the related papers from 2012 to 2022 in the Web of Science Core Collection and China National Knowledge Infrastructure (CNKI). Results: A total of 4 287 English articles and 1 165 Chinese articles were included after screening. At present, the number of foreign literature in the field of cardio-oncology, showed a trend of rapid growth, while our country has "slow development period" and "rapid development period" with 2016 as the boundary. The United States is the country with the largest number of publications in Web of Science, accounting for about 34.21% of the total, followed by China, Italy and other countries. The institutions with the largest number of publications at home and abroad are the University of Texas MD Anderson Cancer Center and the First Affiliated Hospital of Dalian Medical University. Bonnie KY, Ana Barac, Paaladinesh Thavendiranathan are the main contributors abroad, and Xia Yunlong, Zhang Yuhui and Cheng Leilei are the main contributors in China. The most frequently cited literature is the position statement on cancer treatment and cardiovascular toxicity from the European Society of Cardiology. The most frequently used keywords abroad were "heart failure", "breast cancer" and "cardiotoxicity", while the most frequently used keywords in China were "cardiotoxicity", "cardiac tumor" and "doxorubicin". Keywords with the strongest citation bursts at home and abroad in recent three years are "immune checkpoint inhibitors". Conclusion: The research hotspots mainly focus on cardiotoxicity caused by antineoplastic therapy, prevention and treatment, screening and diagnosis of cardiovascular toxicity associated with cancer therapy, etc. Establishing a multidisciplinary diagnosis and treatment model and paying attention to the immune checkpoint inhibitor-related myocarditis and whole process management of cardio-oncology are the directions of future development. [ABSTRACT FROM AUTHOR]

[Purpose/Significance] By analyzing the research situation of global smart agriculture, this paper aims to provide data reference and information support for scientific and technological innovation and management decision-making in the field of smart agriculture in China. [Method/Process] Based on the Web of Science database, this paper makes an in-depth analysis and visualization display of the global smart agriculture research overview, research group competitiveness, research focus and hot spots by using the methods of bibliometrics and knowledge mapping. [Results/Conclusions] Smart agriculture has drawn increasing interest among researchers both in and outside of China since 2010. The productivity and influence of China and the United States are far ahead of those of other countries in the world. The productivity and influence of China Agricultural University, Zhejiang University and the United States Department of Agriculture have obvious advantages. HE Y, JAYAS D S, and BLASCO J have higher productivity and influence, but the quality of papers of Chinese institutions and scholars is generally not rated as high. Agronomy, computer science, engineering, food science and technology, and chemistry are the key disciplines. Computers and Electronics in Agriculture is the most competitive journal. The global and China's smart agriculture can be divided into three research topics, but the research focus is different; the agricultural Internet of things as a representative of information perception, analysis and control technology is a research hotspot in recent years; agricultural sensor independent research and development, data mining analysis and sharing technology model, smart control algorithm model and system integration, smart agricultural machinery equipment and agriculture autonomous research and development of robots and smart agricultural science and technology service mode are the key research directions for further development of smart agriculture in China. [ABSTRACT FROM AUTHOR]

Unmanned Aerial Vehicle(UAV) application in agriculture and forestry has the unique advantages of high efficiency, water and pesticide saving, and strong adaptability to complex terrain. The application research of UAV in agriculture and forestry has shown a fast growing trend. In order to explore the research hotspots and the scientific impact of countries/regions and institutions on UAV application in agriculture and forestry, the relevant literatures in the Web of Science(WoS) core collection database (2011-2020) were collected. The bibliometrics analysis was performed on the journal articles of UAV application in agriculture and forestry based on VOSviewer, WoS analysis tools and Microsoft Excel. The analysis results showed that the number of published papers increased rapidly since 2017, the researches on UAV application in agriculture and forestry were carried out in 94 countries/regions, including1778 institutions. Due to the strong scientific research group in the application of UAV in agriculture and forestry of the United States, China and Australia, a large number of papers had been published, resulting in a great academic influence. Remote sensing was the most widely used technology field of UAV application in agriculture and forestry, mainly involving remote sensing technology, ecological environment science, image processing technology, geological science, etc. Engineering was an important technical field of UAV application in agriculture and forestry, mainly involving control technology, sensor technology and fluid computing modeling technology related to UAV aerial pesticide application.There were 1508 articles and reviews been published in 398 journals, about 1.90% of all journals included in WoS core collection database, indicating that more and more journals paid attention to the application research of UAV in agriculture and forestry. Remote Sensing sponsored by MDPI (Multidisciplinary Digital Publishing Institute) was the journal that published the most of papers, the most cited paper mainly focused on the research status of UAV system in photogrammetry and remote sensing, including sensing, navigation, positioning and general data processing, etc. In addition, the analysis of the research hotspots of UAV application in agriculture and forestry showed that UAV pesticide application, UAV remote sensing of diseases and pests, plant phenotype acquisition were the research hotspots. This study can provide references for innovation research and cooperation between research teams of UAV application in agriculture and forestry. [ABSTRACT FROM AUTHOR]

Objective To visualize and analyze the literature related to immunotherapy for prostate cancer published in the past 20 years through bibliometric analysis, and to explore the research progress and cuttingedge trends in this field. Methods The Web of Science core collection database was searched for literature related to immunotherapy for prostate cancer published from 2002 to 2021. CiteSpace and VOSviewer software were used to visualize and analyze the data and map the evolution of hotspots. Results There were 2 326 papers were finally included after excluding irrelevant studies. The field of immunotherapy for prostate cancer is in a rapid development stage; the United States has a great influence and China has a significant latecomer advantage; the National Cancer Institute, Memorial Sloan-Kettering Cancer Center and University of California, San Francisco are the main research institutions; American authors Gulley JL, Schlom J and Japanese author Itoh K have the highest number of publications. Currently, the main research hotspot is immune checkpoint inhibitors, and high-quality clinical trials are continuing to drive this process forward. Conclusion The exploration of novel immune pathways and the combination of different therapies will be the main trend of future research in immunotherapy for prostate cancer. [ABSTRACT FROM AUTHOR]

Plant functional traits, a bridge between plants and the environment, significantly influence the function of the ecosystem and can reflect the corresponding changes of plants to the environment. The bibliometric method which is a common research tool used in various fields for systematic analysis, which can help us understand the research progress of the relation between plant functional traits and environments and provide reference data for researchers. An effective bibliometric analysis based on the Web of Science database, was carried out to provide insights into research activities on functional traits and environment from 1992 to 2017, especially recent nine years. Thomson Data Analyzer(TDA)and Ucinet, Netdraw, Excel were used for data mining, quantitative analysis and visualization mapping. Analyzed aspects included the number of publications per year, the subject category, main countries and institutes and their comparisons, peridical distributions and highly cited papers. The results were as follows:(1)In the past 26 years, the number of papers on plant functional traits and environmental research increased steadily, especially in the last nine years, the growth accelerated.(2)Research topics mainly centered on specific leaf area, leaf area(index), photosynthesis(photosynthetic characteristics), leaf thickness, leaf shape, leaf nitrogen content, chlorophyll and chlorophyll fluorescence, specific root length, and environmental factors of light, temperature, water(water use efficiency and drought, etc.), ferti-lizer(nitrogen, phosphorus), CO2 and so on. Stoichiometry was widely used in this field.(3)During 2009-2017,European and American developed countries were the main force in this field. The number of American publications and the quality of documents led the world. China ranked the second in the number of articles in the field, ranked only the second to the United States, but the cited frequency and H index of all literatures were low. The Chinese Academy of Sciences ranked the first in the number of publications with absolute advantages, but the quality of the literature needed to be further improved.(4)Top 10 periodicals in this field were of high quality, among these publications eight were JCR division Q1, and the other two were JCR division Q2. Plant and Soil and Plant Ecology ranked the first and the second respectively in terms of article quantity.(5)Top 10 highly cited papers published in eight kinds of periodicals, and the first authors respectively from United States, Netherlands, Canada, Germany and France. [ABSTRACT FROM AUTHOR]

Biological invasions seriously threat the global biodiversity and ecosystem health, causing great losses to global environment and economy. However, rapid climate change could significantly affect the diffusion and invasion of alien species. To explore the development situation of biological invasions under climate change could be helpful for better understanding the status and hot spots in this field, and also the benefitial for understanding the invasion mechanism and making effective management measures. In our study, we studied the Web of Science(WOS)database for publications pertaining to the biological invasions under climate change between the years 1990-2016, we then used the Thomson Data Analyzer(TDA)to operate the systematic analysis. We found that there were total 1 736 published papers in recent 27 years. The number of publications increased annually, while it rapidly increased since 2009. This research area related to several subjects such as environmental science and ecology, biodiversity protection, botany, etc. Prof. Chown SL form Monash University had the largest amounts of publications. USA had the maximum total papers, highly cited and high impact factor papers. California University published the most papers among international research institutes, while the Chinese Academy of Science(CAS)ranked the 10th. Biological Invasions was the academic journal which had the largest publications. Recent studies focused primarily on topics related to species distribution models, biodiversity, global warming and risk assessment. China totally published 52 articles, Chinese Academy of Science had the largest amounts of papers, while Institute of Zoology, Wuhan Botanical Garden, Institute of Botany ranking Top 3 among the branch organizations of CAS. In the future, China should give more attentions on the high level research papers and international cooperation of biological invasions under climate change. In addition, we need to focus on prediction and risk assessment of alien species, relationships between biological invasions and biodiversity, system evolution of invaders, relationships among multiple trophic levels of invaded ecosystem, marine biological invasion, influence of invasion on human health, etc under a rapid global climate change. [ABSTRACT FROM AUTHOR]