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Aiming at the data acquisition and instrument controlling tasks in the single-particle impact test, a high-speed data acquisition program controUed system based on PXIe bus and digitizer was built. Features as high-speed data acquisition and streaming real-time pulse counting data playback, instrument remote control were established. 4 channels, 50 MSPS/Ch sample rate, and 14 bit resolution synchronous data acquisition were accomplished with NI-PXI-5122 digitizer. 380 Mbyte/s throughput data storage for over an hour was achieved using NI-HD-8265 disk array. System software featuring instrument remote control and high performance streaming was developed with Lab-VIEW. The data acquisition and streaming performance of the system was tested in simulated experiment platform with 6µs width pulse signal. The result indicates that the system is capable to acquired and stream high speed data for several hours, and accomplish demanded functions as real-time pulse counting data playback and instrument remote control. [ABSTRACT FROM AUTHOR]

In order to establish a clear relationship between the biological electrical characteristics and biochemical characteristics, an inter-digitated gold electrode was designed and manufactured on a silica glass substrate by using micro-processing technolog. Based on this substrate, a cell electrical measurement device that can measure continuous impedance spectroscopy in real-time was then fabricated. Cervical cancer cell was planted and then growing on the measurement cell. Impedance spectroscopy of the cell was then measured with Parstat4000, with frequency varying from 1 Hz to 1 MHz. Based on existed equivalent circuit model, a corrected model of interdigital electrodes was proposed. The result indicates that the variance of the conrcted model is smaller than the original model. The parameters of corncted model can be devided into two sets which reflect the change of character of the solution and the cells while the cells were growing. Finally, a qualitative relationship between the impedance data and cell physiological change was build. [ABSTRACT FROM AUTHOR]