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Short bowel syndrome (SBS) is the most common cause of intestinal failure in children. The main goal of management of SBS is to achieve enteral autonomy using appropriate intestinal rehabilitation program. For this purpose, it is necessary to occur small bowel adaptation with subsequent structural and functional changes. Enteral foods are necessary factor stimulating the adaptation. Children with SBS have pronounced malabsorption, which requires careful monitoring of anthropometric and laboratory parameters to prevent nutrient deficits and to maintain adequate growth and development. Multidisciplinary approach in the care of these children is of particular importance. [ABSTRACT FROM AUTHOR]