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There are scanty of available data about the management of myoma of the uterus during pregnancy and birth. The authors describe two cases of such a pathology--big myoma of the uterus > 10 sm diameter (d.), who were treated conservatively and ended successfully, without serious complications. The pregnant women were done cesarean section and during the operation the myomas were excisiert. There were no complications intra- and postoperationem. The authors suggest that myectomy during pregnancy and cesarean section must not be don routinely.

The quick increase of morbidity, caused by the endometrial carcinoma in our country during recent 15 years from 5,2 to 16,5 per 100,000 raises acutely the question about effective primary and secondary prophylaxis. Having in mind the role of hyperestrogenemia in the etiology of endometrial carcinoma and the fact that the results from its treatment are determined basically by the degree of distribution of the tumor, the authors think that it is necessary fight for rational feeding, timely treatment of the disease with hyperestrogenemia and prophylactic therapy with gestagens. Cytologic examination of aspirate, obtained from the uterine cavity, is proposed as screening method for women of the risk groups. A scheme of management of women with pathological R3-5 group is proposed.