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A field experiment was carried out for two seasons 2001 and 2002 at Ismailia Agric. Res. Station to study the comparative effect of farmyard manure (FYM) application, individually or in combination with natural minerals, as sources of micronutrients. Such effect was studied during successive growth stages of wheat (vegetative stage, flowering stage and harvest stage), as well as after maize harvesting, on plant growth, nutrients uptake and wheat - maize productivity. The experiment was designed in a randomized complete block design with three replications. Two levels of FYM (2 % and 3 %) and three natural minerals, i.e., magnetite (iron oxide, Mag.), basic slag (Bas.) and manganese dust (Md.) at three rates 0.02 %, 0.05 % and 0.07%, respectively. Obtained results revealed that, at vegetative stage, mineral fertilizers (MF) treatment positively affected the dry matter of both shoots and roots of wheat plants along with contents of nitrogen and potassium in both shoots and roots as well as shoot/root ratios. At flowering stage, obtained data showed that applied farmyard manure at the rate of 3 % (F2) significantly affected the dry matter of both shoots and roots as well as their contents of N, P and K. A similar trend was obtained for micronutrients uptake at the two indicated growth stages of wheat, which recorded high values when FYM, at a rate of 3 % (F2), was applied. On the other hand, obtained results indicated that applied FYM at the rate of 2 % (F1) with high rate (0.07 %) of each of the used natural minerals and FYM at the rate of 3 % (F2) in combination with the moderate rate (0.05 %) of such minerals recorded high values of all tested parameters. In addition, Basic slag (Bas.), generally, gave the highest values, over control, of dry matter content and macronutrients uptake during the studied two growth stages of wheat, (vegetative and flowering stages). The agronomic yield components of wheat (straw, grains and weight of 1000 grains) were increased when MF was applied; such significant increases were obtained in maize yield (residual effect) as a result of applied FYM individually or combined with natural minerals.