The codling moth Cydia pomonella L. (Tortricidae: Lepidoptera) is considered as a key pest of Apple crop in Syria, field experiments were conducted in 2012, 2013 and 2014 on apple trees of Golden and Starkin cultivars at field (19) in the Scientific Agricultural Research Center of Swieda, Syria and a field followed to state farms of Mafalae. In biological treatment, weekly interval releases of Trichogramma cacocae Marchal were done during the whole growing season until harvest on the two apple cultivars. The trees of fence which surrounding biological treatment were treated with traditional insecticides (Delta Permethrin, Dimethoate and Chlorine Perfos Ethyl) to be remained within the effectiveness of insecticides throughout the growing season and in addition, a control treatment was untreated. Results were evaluated by using injury rates, productivity and efficacy of biological and chemical treatments during the season and at harvest. Low density of the pest was recorded in the field (19) compared to Mafalae field. Significant differences of injury rates of the codling moth were recorded between biological treatment and control. No significant differences were recorded between Golden and Starkin cultivars for injury rates of the codling moth in the two fields except in the second year in the field (19) were represented for Starkin delicious. For productivity, no significant differences were recorded between the two cultivars in the first and the second year, while it were recorded in 2014 in Mafalae for Golden delicious, 49.72 as compared to 36.19 kg/tree for Starkin, in biological treatment the averages of production 11.33 and 17.83 kg/tree for Golden and Starkin delicious with nosignificant differences were represented respectively in the field (19), at the last year of the experiment. The highest efficacy values of Trichogramma at harvest in the last year were recorded 65.04 and 70.68% in Mafalae and 69.1 and 72.69 % in (19) field in Golden and Starkin delicious, respectively. [ABSTRACT FROM AUTHOR]