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This paper argues that the manner in which scholarship peer review as a process of scientific quality is conducted and perceived in the editorial arena is a cause of insufficient knowledge production in Africa and developing countries. Argument still persist that the developing countries such as Africa contributes at least 1.25% of the world knowledge production. This paper does not aim to purport the idea that the peer review process of scholarship in the publication of scientific material is unnecessary, but argues that the manner of using it to judge scholarship quality is often flawed in many academic publications. This paper uses analytical approach from literature sources to argue that the usage of peer review without considering the complex process affecting peer review will result in the death of knowledge in academic enterprise of developing countries such as Africa. This paper concludes that only if editors of scientific publishing can conduct peer review in an ethical manner without biasedly directing knowledge, knowledge generation will increase to solve economic problems in Africa. https://doi.org/10.19108/KOERS.83.1.2314