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Start Over Author "Gläser E" Journal zentralblatt fur chirurgie
2 results on '"Gläser E"'

2. [Prevention of thromboembolism in spinal fractures with spinal cord injuries. Standard heparin versus low-molecular-weight heparin in acute paraplegia].

Author

Lohmann U, Gläser E, Braun BE, and Bötel U

Subjects
Acute Disease, Adolescent, Adult, Aged, Aged, 80 and over, Dose-Response Relationship, Drug, Drug Administration Schedule, Female, Heparin administration & dosage, Heparin adverse effects, Humans, Long-Term Care, Male, Middle Aged, Paraplegia complications, Prospective Studies, Spinal Cord Injuries complications, Spinal Fractures complications, Thromboembolism etiology, Treatment Outcome, Heparin, Low-Molecular-Weight administration & dosage, Paraplegia drug therapy, Spinal Cord Injuries drug therapy, Spinal Fractures drug therapy, Thromboembolism prevention & control
Abstract

In a prospective, randomized, open study, the therapeutic efficacy of a long-term prophylaxis with standard heparin (SH) was compared with that of low-molecular-weight heparin (LMWH) Dalteparin in 166 patients who had spinal fractures with spinal cord injury. 86 patients were treated with SH 2 x 7500 U s.c. and 80 patients were treated with LMWH 1 x 5000 anti-Xa U s.c. once daily. The screening was implemented by daily bedside-examination. In case of clinical thromboembolism-symptoms patients had confirmatory venography or lung scans. In the SH-group 12 (14.0%) patients had deep vein thrombosis and in the LMWH-group 6 (7.5%). Pulmonary embolism was detected two times in the SH-group (2.33%) and only one time in the LMWH-group (1.25%). A significant difference could not be shown, but is descriptive evident.

Published
2001
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